Patents by Inventor Walker Lahr

Walker Lahr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENHANCING EFFICIENCY OF TARGETED GENE KNOCKIN BY BASE EDITORS
    Publication number: 20240101993
    Abstract: The present invention provides genomic engineering methods that utilize base editors to perform targeted gene knockins and gene knockouts with high efficiency. Cells that have been genetically modified according to these methods are also provided, as are methods of using the modified cells in a treatment for cancer.
    Type: Application
    Filed: January 21, 2022
    Publication date: March 28, 2024
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Beau R. Webber, Branden S. Moriarity, Walker Lahr, Nicholas Slipek, Mitchell G. Kluesner
  • LYMPHOHEMATOPOIETIC ENGINEERING USING CAS9 BASE EDITORS
    Publication number: 20210040507
    Abstract: Provided herein are methods and systems for targeted gene disruption (knock-out, missense mutation) and targeted gene knock-in in mammalian cells using base editors and guide RNAs (gRNAs) designed to target splice acceptor-splice donor sites. Also provided herein are universally acceptable genetically engineered cells comprising targeted disruptions in immunotherapy-related genes and comprising a CAR/TCR for therapeutic applications.
    Type: Application
    Filed: March 13, 2019
    Publication date: February 11, 2021
    Inventors: Branden Moriarity, Beau Webber, Cara-Lin Lonetree, Miechaleen Diers, Mitchell Kluesner, Walker Lahr, Emily Joy Pomeroy