Abstract: The present disclosure relates to AM-14 pharmaceutical formulations and therapeutic dosing regimens for the treatment of disease.

Abstract: The present disclosure relates to AM-14 pharmaceutical formulations and therapeutic dosing regimens for the treatment of disease.

Abstract: The present disclosure relates to AM-14 pharmaceutical formulations and therapeutic dosing regimens for the treatment of disease.

Abstract: The present disclosure relates to AM-14 pharmaceutical formulations and therapeutic dosing regimens for the treatment of disease.

Abstract: The present disclosure relates to ?M-14 pharmaceutical formulations and therapeutic dosing regimens for the treatment of disease.

Abstract: The present disclosure relates to AM-14 pharmaceutical formulations and therapeutic dosing regimens for the treatment of disease.

Abstract: The present disclosure relates to AM-14 pharmaceutical formulations and therapeutic dosing regimens for the treatment of disease.

Abstract: The present disclosure relates to AM-14 pharmaceutical formulations and therapeutic dosing regimens for the treatment of disease.

Abstract: The present invention relates to a method and a device for assigning an electronic wheel unit, which is assigned to a wheel of a vehicle and is for ascertaining at least one characteristic parameter of the wheel, to a side of the vehicle. In this case, a direction of rotation of the wheel is determined by means of the wheel unit. The direction of rotation of the wheel which is determined by means of the wheel unit is compared with a direction of rotation of another wheel which is determined by means of another wheel unit assigned to the other wheel, wherein the wheel and the other wheel are arranged on different sides of the vehicle on a shared axle. Depending on the comparison of the determined directions of rotation of the wheel and of the other wheel, the wheel unit is assigned on the basis of a first procedure for assigning the wheel unit to the side of the vehicle or on the basis of a second procedure for assigning the wheel unit to the side of the vehicle.

Abstract: A spool for a fishing reel is disclosed to include an axle, which has a surface and a recess curved inwards from the surface, two sidewalls radially extending from the two distal ends of the axle, and a pin, which is disposed in the recess with the topmost edge thereof kept in flush with the surface of the axle for the fastening of a fishing line for allowing the spool to take up or let off the fishing line smoothly.

Abstract: In order to produce a safing concept, an extra-safing-sensor in the control unit (ECU) is foregone and the safing function from one of the available acceleration or turn-rate sensors (S1 to S5) is replaced. Furthermore a pre-stage is connected to the firing element (Z1, Z2), before the existing firing path, which, depending upon the sensor signals as analysed by the controller unit (1), controls a safety switch (T11), in series with the firing switches and the firing element.

Abstract: A fishing reel has a spool for retaining a line thereon, a transmission assembly for driving the spool reciprocated along an elongated orientation thereof and a crank for driving the transmission assembly to wind the line on the spool, wherein the transmission assembly has at least an elliptical wheel to make the line wound on the spool in a uniform distribution.

Abstract: A fishing reel has a spool for retaining a line thereon, a transmission assembly for driving the spool reciprocated along an elongated orientation thereof and a crank for driving the transmission assembly to wind the line on the spool, wherein the transmission assembly has at least an elliptical wheel to make the line wound on the spool in a uniform distribution.

Abstract: A method for controlling an emergency power supply of at least two power loads, includes steps of: assigning an energy storage device of the power supply to one of the at least two power loads; and after a failure of a power source for a predetermined autarchy time period, using the energy storage device to ensure that power is supplied to the one of the at least two power loads; and after an occurrence of at least one predetermined condition, using residual energy present in the energy storage device to supply power to another one of the at least two power loads. Preferably a firing device of a vehicle occupant protection system is used as one of the power loads.

Abstract: In order to produce a safing concept, an extra-safing-sensor in the control unit (ECU) is foregone and the sating function from one of the available acceleration or turn-rate sensors (S1 to S5) is replaced. Furthermore a pre-stage is connected to the firing element (Z1, Z2), before the existing firing path, which, depending upon the sensor signals as analysed by the controller unit (1), controls a safety switch (T11), in series with the firing switches and the firing element.

Abstract: An implant, in particular an intervertebral prosthesis, which consists of an elongated elastic body which is form-elastic and takes on the form of a spiral S in the force free state. The spiral can be drawn by a reverse winding up into an insertion instrument which is only insubstantially larger in the insertion region than the cross-section of the elongated elastic body in order to reach the inner space of an intervertebral disc through a small opening in the annulus fibrosus and to push in and sever off the self winding spiral when the interior is filled. This has the advantage that inner spaces of differing sizes can be filled with the same spiral.

Abstract: Two different switching signals for switching through the safety switching element (22) for the second firing stage of an occupant protection component which can be triggered in multiple stages are formed in the control device (3). The two switching signals are emitted to different outputs (14, 16) of the control device (3) and then subjected to an AND operation.

Abstract: A capacitance of a firing capacitor for the firing of a firing pellet, where the firing capacitor is contained in an occupant protection system of a motor vehicle, is implemented on a rising edge of a capacitor voltage in a charging phase. For this purpose, a quantity of charge taken up by the storage capacitor during a test time interval is determined by measurement of a charge current or of a corresponding value and integration over the test time interval. The capacitance is obtained through a quotient of the resultant integral and a voltage change in the capacitor voltage that occurred in the test time interval. The functional availability of the firing capacitor is not adversely affected at any time during the testing.

Abstract: A method for controlling an emergency power supply of at least two power loads, includes steps of: assigning an energy storage device of the power supply to one of the at least two power loads; and after a failure of a power source for a predetermined autarchy time period, using the energy storage device to ensure that power is supplied to the one of the at least two power loads; and after an occurrence of at least one predetermined condition, using residual energy present in the energy storage device to supply power to another one of the at least two power loads. Preferably a firing device of a vehicle occupant protection system is used as one of the power loads.

Abstract: In a fishing reel of the type in which the spool for receiving the fishing line is caused to more to and fro in the direction of its winding axis in response to a cam drive for driving a spindle attached to the spool, the cam drive including a guide part with a guide slot into which projects an eccentrically mounted cam stud, the guide slot is in the form of an elongated S in order to impart an acceleration to the spool at its reversing points, and thereby prevent formation of bulges at the sides of the spool during winding. The locations in the guide slot corresponding to reversing points of the spool are offset from a center line of the guide slots along a longitudinal axis of the slot in a direction perpendicular to the stroke direction, resulting in the above-described acceleration and also having the effect of increasing displacement of the cam drive mechanism in the stroke direction.