Abstract: Process for the preparation of cephem compounds of the formula ##STR1##

Abstract: The invention relates to cephem derivatives of the general formula I ##STR1## and their physiologically acceptable acid addition salts, to pharmaceutical formulations active against bacterial infections, to processes for preparing the compounds and formulations, and to the use of the compounds for combating bacterial infections.

Abstract: Anhydrous crystalline (6R,7R)-7-[(Z)-2-(2-aminothiazol-4-yl)-2-(2-carboxyprop-2-oximino)acetamid o]-3-(1-pyridiniummethyl)-3-cephem-4-carboxylate and a process for its preparation, a pharmaceutical formulation which is active against bacterial infections and contains this compound and a process for the preparation of the formulation and the use of this compound for controlling bacterial infections.

Abstract: Crystalline cephem-acid addition salts of the formula ##STR1## and their hydrates, processes for the preparation of the acid addition salts, pharmaceutical products containing these compounds and processes for their preparation, and the use of the compounds for combating bacterial infections.

Abstract: What are disclosed are cephalosporin compounds of the formula ##STR1## pharmaceutical preparations which are active against bacterial infections and in which these cephem compounds are present, process for the preparation of the cephem compounds and of the pharmaceutical preparations, use of the cephem compounds for combating bacterial infections, and compounds used as starting materials in the synthesis of said cephem compounds.

Abstract: 3-Aryl-7-chloro-3,4-dihydroacridine-1,9(2H,10H)-dione 1-oximes and 1-hydrazone derivatives of the formula I ##STR1## and their physiologically tolerated acid addition and ammonium salts are described, as is a process for their preparation. The new compounds are chemotherapeutic agents and are active against protozoa, especially malaria plasmodia.

Abstract: A crystalline water soluble disodium salt of 7-.beta.-[2-(2-aminothiazol-4-yl)-2-syn-methoximinoacetamido]-3-(5-carboxy methyl-4-methyl-1,3-thiazol-2-ylthiomethyl)ceph-3-em-4-carboxylic acid (cefodizim), or an adduct or solvate thereof with water and/or an organic solvent.

Abstract: What are disclosed are cephem compounds of the formula ##STR1## useful for combating bacterial infections, and methods of making and using the same.

Abstract: What are disclosed are cephem compounds of the formula ##STR1## in which R.sub.1 denotes hydrogen, an optionally substituted alkyl, acyl, arylsulfonyl or alkylsulfonyl group or an amino-protective group which is known from peptide chemistry, R.sub.2 denotes hydrogen or an optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, aralkyl, acyl, aryl, arylsulfonyl, alkylsulfonyl or heterocyclic group, R.sub.3 denotes hydrogen, an ester group or a cation, R.sub.4 denotes hydrogen, a lower alkoxy group or a group which can be converted to this, X denotes a SO group in the R or S configuration or a SO.sub.2 group and A denotes hydrogen, an optionally substituted alkoxy or alkenyloxy group, halogen or a group --CH.sub.2 Y, in which Y represents hydrogen, halogen or the radical of a nucleophilic compound, and in which the R.sub.

Abstract: Cephalosporin derivatives of the formula ##STR1## processes for their manufacture and their use for combating bacterial infections.

Abstract: Antimalarial compositions are disclosed containing as the active ingredient a mixture of a tetrahydroacridone of the general formula I ##STR1## in which R.sup.1 represents methyl, phenyl, p-chlorophenyl, m-chlorophenyl, p-fluorophenyl, p-trifluoromethylphenyl, o-trifluoromethylphenyl or o-chloro-p-trifluoromethylphenyl,R.sup.2 represents hydrogen or methyl, andR.sup.3 represents fluorine or chlorine,or a salt of such a compound with a physiologically compatible acid or base, with(a) 6-methoxy-.alpha.-(5-vinyl-2-quinuclidinyl)-4-quinoline-methanol (Quinine),(b) 7-chloro-4-(diethylamino-1-methyl-butylamino)-quinoline (Chloroquine),(c) .alpha.

Abstract: What is disclosed are cephalosporin compounds of the formula ##STR1## pharmaceutical preparations having an action against bacterial infections and containing such cephem compounds, a process for the manufacture of the cephem compounds and of pharmaceutical preparations containing the same, and the use of the cephem compounds to combat bacterial infections.

Abstract: Cephem derivatives of the general formula ##STR1## in which the R.sub.2 O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.

Abstract: Antimalarial compositions are disclosed containing as the active ingredient a mixture of a tetrahydroacridone of the general formula I ##STR1## in which R.sup.1 represents methyl, phenyl, p-chlorophenyl, m-chlorophenyl, p-fluorophenyl, p-trifluoromethylphenyl, o-trifluoromethylphenyl or o-chloro-p-trifluoromethylphenyl,R.sup.2 represents hydrogen or methyl, andR.sup.3 represents fluorine or chlorine,or a salt of such a compound with a physiologically compatible acid or base, with(a) 6-methoxy-.alpha.-(5-vinyl-2-quinuclidinyl)-4-quinoline-methanol (Quinine),(b) 7-chloro-4-(diethylamino-1-methyl-butylamino)-quinoline (Chloroquine),(c) .alpha.

Abstract: Antibacterially-active tetracyclines, substituted at the amide group, and physiologically-tolerable salts thereof, said tetracyclines having the formula ##SPC1##Methods of making the same; pharmaceutical compositions containing the same.

Abstract: 2-Carboxamido-substituted tetracyclines of the general formula ##SPC1##A process for their preparation and compositions containing these compounds.

Abstract: Tetrahydroacridones and their salts with physiologically tolerated acids and bases and process for preparing them. The compounds have a valuable chemotherapeutic action and may be used as drugs against protozoan diseases.