Patents by Inventor Walter E. DeWolf

Walter E. DeWolf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fab I inhibitors
    Patent number: 7557125
    Abstract: Compounds of the formula (I) are disclosed which are Fab I inhibitors and are useful in the treatment of bacterial infections.
    Type: Grant
    Filed: December 9, 2004
    Date of Patent: July 7, 2009
    Assignee: Affinium Pharmaceuticals, Inc.
    Inventors: William H. Miller, Kenneth A. Newlander, Mark A. Seefeld, Irene N. Uzinskas, Walter E. DeWolf, Dalia R. Jakas
  • Fab I Inhibitors
    Publication number: 20080125423
    Abstract: Compounds of the formula (I) are disclosed which are Fab I inhibitors and are useful in the treatment of bacterial infections.
    Type: Application
    Filed: July 18, 2007
    Publication date: May 29, 2008
    Inventors: William H. Miller, Kenneth A. Newlander, Mark A. Seefeld, Irene N. Uzinskas, Walter E. Dewolf, Dalia R. Jakas
  • METHODS OF SCREENING FOR FABK ANTAGONISTS AND AGONISTS
    Publication number: 20040137548
    Abstract: The invention provides methods for identifying agonists and antagonists of FabK polypeptides.
    Type: Application
    Filed: October 1, 2001
    Publication date: July 15, 2004
    Inventors: Walter E. DeWolf, David John Payne, Nicola Gail Wallis, Joshua M. West
  • Methods of agonizing and antagonizing FabK
    Publication number: 20040053814
    Abstract: The invention provides methods for using agonists and antagonists of FabK polypeptides, particularly to modulate the metabolism of bacteria or to treat bacterial infection.
    Type: Application
    Filed: April 4, 2003
    Publication date: March 18, 2004
    Inventors: Martin Brandt, Walter E. Dewolf, Paul M. Keller, Arunbhai H. Patel, David J. Payne, Shannon L. Reed, Mark A. Seefeld, David G. Tew, Nicola G. Wallis, Joshua M. West
  • FabK variant
    Publication number: 20030175758
    Abstract: The invention provides FabK polypeptides and polynucleotides encoding FabK polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are preferred methods for utilizing FabK polypeptides and polynucleotides as diagnostic reagents and in diagnostic assays to screen for microbial infections in organisms and infestations in materials.
    Type: Application
    Filed: November 26, 2002
    Publication date: September 18, 2003
    Applicant: SmithKline Beecham Corporation
    Inventors: Walter E. DeWolf, David John Payne, Nicola Gail Wallis, Joshua M. West
  • FabK variant
    Publication number: 20030175757
    Abstract: The invention provides FabK polypeptides and polynucleotides encoding FabK polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing FabK polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: November 26, 2002
    Publication date: September 18, 2003
    Applicant: SmithKline Beecham Corporation
    Inventors: Walter E. DeWolf, David John Payne, Nicola Gail Wallis, Joshua M. West