Patents by Inventor Walter Fischli

Walter Fischli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diazabicyclononene derivatives and use thereof
    Patent number: 7915259
    Abstract: The invention relates to a novel 3,9-diazabicyclo[3.3.1]nonene derivative of formula (I), enantiomers thereof, and their use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing at least one compound of formula (I): or (I?): and especially their use as inhibitors of renin.
    Type: Grant
    Filed: January 26, 2006
    Date of Patent: March 29, 2011
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Olivier Bezencon, Daniel Bur, Walter Fischli, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Thomas Weller
  • Sulfamides as endothelin receptor antagonists for the treatment of cardiovascular diseases
    Patent number: 7868012
    Abstract: The invention relates to novel sulfamic acid amides and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and especially their use as endothelin receptor antagonists.
    Type: Grant
    Filed: November 11, 2005
    Date of Patent: January 11, 2011
    Assignee: Actelion Pharmaceuticals, Ltd.
    Inventors: Martin Bolli, Christoph Boss, Martine Clozel, Walter Fischli, Thomas Weller
  • NOVEL PIPERIDINE CARBOXYLIC ACID AMINE DERIVATIVES
    Publication number: 20100324052
    Abstract: The invention relates to novel piperidine carboxylic acid amide derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of these novel compounds, pharmaceutical compositions comprising such compounds and especially the use of such compounds as inhibitors of renin.
    Type: Application
    Filed: August 12, 2010
    Publication date: December 23, 2010
    Inventors: Olivier Bezencon, Christoph Boss, Daniel Bur, Austin Chih-Yu Chen, Olivier Corminboeuf, Daniel Dube, Walter Fischli, Corinna Grisostomi, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Michel Therien, Thomas Weller
  • SUBSTITUTED 1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES
    Publication number: 20100256182
    Abstract: The invention relates to novel 1,2,3,4-tetrahydroisoquinoline derivatives of formula (I) wherein R1, R2, R3 and X are as defined in the claims, and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and methods of treatment comprising administration of said compounds to a mammal.
    Type: Application
    Filed: June 15, 2010
    Publication date: October 7, 2010
    Inventors: Hamed Aissaoui, Martine Clozel, Walter Fischli, Ralf Koberstein, Thomas Weller
  • Piperidine carboxylic acid amide derivatives
    Patent number: 7799805
    Abstract: The invention relates to novel piperidine carboxylic acid amide derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of these novel compounds, pharmaceutical compositions comprising such compounds and especially the use of such compounds as inhibitors of renin.
    Type: Grant
    Filed: May 23, 2006
    Date of Patent: September 21, 2010
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Olivier Bezencon, Christoph Boss, Daniel Bur, Austin Chih-Yu Chen, Olivier Corminboeuf, Daniel Dube, Walter Fischli, Corinna Grisostomi, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Michel Therien, Thomas Weller
  • Substituted 1,2,3,4-tetrahydroisoquinoline derivatives
    Patent number: 7763638
    Abstract: The invention relates to novel 1,2,3,4-tetrahydroisoquinoline derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and methods of treatment comprising administration of said compounds to a mammal.
    Type: Grant
    Filed: February 23, 2005
    Date of Patent: July 27, 2010
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Hamed Aissaoui, Martine Clozel, Walter Fischli, Ralf Koberstein, Thomas Weller
  • Thiophene derivatives
    Patent number: 7750040
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Grant
    Filed: July 20, 2005
    Date of Patent: July 6, 2010
    Inventors: Martin Bolli, Daniel Bur, Martine Clozel, Walter Fischli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Thomas Weller
  • Bicyclononene derivaties
    Publication number: 20090306123
    Abstract: The invention relates to novel bicyclononene derivatives of Formula (I); and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
    Type: Application
    Filed: August 22, 2005
    Publication date: December 10, 2009
    Inventors: Olivier Bezencon, Christoph Boss, Daniel Bur, Olivier Corminboeuf, Walter Fischli, Corinna Grisostomi, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Thomas Weller
  • 7-ARYL-3, 9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES
    Publication number: 20080312242
    Abstract: The invention relates to novel 3,9-diazabicyclo[3.3.1]nonene derivatives of formula (I) and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors or renin.
    Type: Application
    Filed: July 7, 2008
    Publication date: December 18, 2008
    Applicant: ACTELION PHARMACEUTICALS, LTD.
    Inventors: OLIVIER BEZENCON, DANIEL BUR, WALTER FISCHLI, LUBOS REMEN, SYLVIA RICHARD-BILDSTEIN, HANS-PETER WEBER, THOMAS WELLER
  • Pyrimidine-sulfamides and their use as endothelian receptor antagonist
    Patent number: 7452896
    Abstract: The invention relates to novel sulfamic acid amides of General Formula (I) and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as endothelin receptor antagonists.
    Type: Grant
    Filed: November 10, 2003
    Date of Patent: November 18, 2008
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, Christoph Boss, Martine Clozel, Walter Fischli, Thomas Weller
  • Sulfonylamino-acetic acid derivatives
    Patent number: 7435815
    Abstract: The invention relates to novel sulfonylamino-acetic acid derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of such compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as orexin receptor antagonists.
    Type: Grant
    Filed: May 31, 2007
    Date of Patent: October 14, 2008
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Hamed Aissaoui, Martine Clozel, Walter Fischli, Ralf Koberstein, Thierry Sifferlen, Thomas Weller
  • Novel Tetrahydropyridine Derivatives
    Publication number: 20080234305
    Abstract: The invention relates to novel tetrahydropyridine derivatives and use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
    Type: Application
    Filed: October 5, 2004
    Publication date: September 25, 2008
    Inventors: Olivier Bezencon, Daniel Bur, Walter Fischli, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Thomas Weller
  • 7-aryl-3,9-diazabicyclo(3.3.1)non-6-ene derivatives and their use as renin inhibitors in the treatment of hypertension, cardiovascular or renal diseases
    Patent number: 7427613
    Abstract: The invention relates to novel 3,9-diazabicyclo[3.3.1]nonene derivatives of formula (I) and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors or renin.
    Type: Grant
    Filed: April 8, 2003
    Date of Patent: September 23, 2008
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Olivier Bezencon, Daniel Bur, Walter Fischli, Lubos Remen, Sylvia Richard-Bildstein, Hans-Peter Weber, Thomas Weller
  • Novel Piperidine Carboxylic Acid Amide Derivatives
    Publication number: 20080214598
    Abstract: The invention relates to novel piperidine carboxylic acid amide derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of these novel compounds, pharmaceutical compositions comprising such compounds and especially the use of such compounds as inhibitors of renin.
    Type: Application
    Filed: May 23, 2006
    Publication date: September 4, 2008
    Applicant: ACTELION PHARMACEUTICALS LTD
    Inventors: Olivier Bezencon, Christoph Boss, Daniel Bur, Austin Chih-Yu Chen, Olivier Corminboeuf, Daniel Dube, Walter Fischli, Corinna Grisostomi, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Michel Therien, Thomas Weller
  • Diazabicyclononene Derivatives and Use Thereof
    Publication number: 20080161313
    Abstract: The invention relates to a novel 3,9-diazabicycl?[3.3.1]nonene derivative of formula (I) and the enantiomers thereof and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing at least one compound of formula (I) or (I?) and especially their use as inhibitors of renin.(I).
    Type: Application
    Filed: January 26, 2006
    Publication date: July 3, 2008
    Applicant: ACTELION PHARMACEUTICALS LTD
    Inventors: Oliver Bezencon, Daniel Bur, Walter Fischli, Lubos Remen, Sylvia Richard-Bildstein, Thierry Sifferlen, Thomas Weller
  • Novel Thiophene Derivatives
    Publication number: 20080064740
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: July 20, 2005
    Publication date: March 13, 2008
    Applicant: ACTELION PHARMACEUTICALS, LTD.
    Inventors: Martin Bolli, Daniel Bur, Martine Clozel, Walter Fischli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Thomas Weller
  • Alkansulfonamides as endothelin antagonists
    Patent number: 7323465
    Abstract: The invention relates to novel alkansulfonamides of structure (I), wherein R1 is a lowel alzyl group and the other variables are as defined in the description, and their use as active ingredients in the preparation of pharmaceutical compositions.
    Type: Grant
    Filed: December 10, 2002
    Date of Patent: January 29, 2008
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, Christoph Boss, Martine Clozel, Walter Fischli, Thomas Weller
  • Sulfamides as Endothelin Receptor Antagonists for the Treatment of Cardiovascular Diseases
    Publication number: 20080004298
    Abstract: The invention relates to novel sulfamic acid amides and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and especially their use as endothelin receptor antagonists.
    Type: Application
    Filed: November 11, 2005
    Publication date: January 3, 2008
    Applicant: ACTELION PHARMACEUTICALS LTD.
    Inventors: Martin Bolli, Christoph Boss, Martine Clozel, Walter Fischli, Thomas Weller
  • Sulfamides and their use as endothelin receptor antagonists
    Patent number: 7285549
    Abstract: The invention relates to novel sulfamides and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as endothelin receptor antagonists.
    Type: Grant
    Filed: April 7, 2006
    Date of Patent: October 23, 2007
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, Christoph Boss, Walter Fischli, Martine Clozel, Thomas Weller
  • SULFONYLAMINO-ACETIC ACID DERIVATIVES
    Publication number: 20070244156
    Abstract: The invention relates to novel sulfonylamino-acetic acid derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of such compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as orexin receptor antagonists.
    Type: Application
    Filed: May 31, 2007
    Publication date: October 18, 2007
    Applicant: ACTELION PHARMACEUTICALS LTD.
    Inventors: Hamed Aissaoui, Martine Clozel, Walter Fischli, Ralf Koberstein, Thierry Sifferlen, Thomas Weller