Patents by Inventor Walter-Gunar Friebe

Walter-Gunar Friebe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ether derivatives
    Patent number: 7432291
    Abstract: The present invention provides the compounds of formula (I) their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
    Type: Grant
    Filed: March 17, 2005
    Date of Patent: October 7, 2008
    Assignee: Hoffman-La Roche Inc.
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Thomas Friess, Ulrike Reiff, Edgar Voss
  • Oxidized thioether derivatives
    Patent number: 7405231
    Abstract: The present invention provides the compounds of formula I their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: July 29, 2008
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Thomas Friess, Lothar Kling, Matthias Rueth, Edgar Voss
  • Triazole derivatives
    Patent number: 7288557
    Abstract: The present invention relates to the compounds of formula I their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, compositions containing such compounds and their manufacture, as well as the use of such compounds in the control or prevention of illnesses such as cancer.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: October 30, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Walter-Gunar Friebe, Ulrike Reiff, Thomas von Hirschheydt, Edgar Voss
  • Arylazole derivatives, their manufacture and use as pharmaceutical agents
    Patent number: 7259262
    Abstract: There are presented compounds of formula (I) their pharmaceutically acceptable salts, enantiomeric forms thereof, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
    Type: Grant
    Filed: October 15, 2004
    Date of Patent: August 21, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Ulrike Reiff, Matthias Rueth, Edgar Voss
  • Oxazoles, their manufacture and use as pharmaceutical agents
    Patent number: 7247649
    Abstract: The present invention relates to novel oxazoles of formula (I) their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
    Type: Grant
    Filed: August 3, 2004
    Date of Patent: July 24, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Ulrike Reiff, Matthias Rueth, Edgar Voss
  • Pentafluorosulfanyl compounds
    Patent number: 7235574
    Abstract: The present invention provides the compounds of formula I-A their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: June 26, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Guy Georges, Matthias Rueth, Edgar Voss
  • Aniline derivatives, their manufacture and use as pharmaceutical agents
    Patent number: 7205326
    Abstract: Compounds of formula (I) are useful in the therapy and/or prevention of illnesses with known over-expression of receptor tyrosine kinases of the HER-family like HER-2 and EGFR (HER-1). Accordingly, these compounds are useful for the treatment of diseases such as cancer in humans or animals.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: April 17, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Ulrike Reiff, Matthias Rueth, Edgar Voss
  • Oxazole derivatives
    Patent number: 7205325
    Abstract: The present invention 1 includes compounds of formula (I), and their pharmaceutically acceptable salts. These compounds are useful in the control or prevention of cancer.
    Type: Grant
    Filed: March 25, 2004
    Date of Patent: April 17, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Thomas Friess, Bernhard Goller, Matthias Rueth, Edgar Voss
  • Diazine derivatives
    Patent number: 7179812
    Abstract: The present invention provides compounds of formula (I): their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
    Type: Grant
    Filed: March 31, 2005
    Date of Patent: February 20, 2007
    Assignee: Hoffmann-la Roche Inc.
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Wolfgang Jenni, Matthias Rueth, Edgar Voss
  • Benzylether derivatives
    Patent number: 7163953
    Abstract: Objects of the present invention are the compounds of formula (I) their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
    Type: Grant
    Filed: May 18, 2005
    Date of Patent: January 16, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Thomas Friess, Christian Geletneky, Guy Georges, Irene Kolm, Edgar Voss
  • Triazole derivatives
    Publication number: 20060211750
    Abstract: The present invention relates to the compounds of formula I their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, compositions containing such compounds and their manufacture, as well as the use of such compounds in the control or prevention of illnesses such as cancer.
    Type: Application
    Filed: September 14, 2005
    Publication date: September 21, 2006
    Inventors: Walter-Gunar Friebe, Ulrike Reiff, Thomas von Hirschheydt, Edgar Voss
  • Amino alcohol derivatives, process for their production and pharmaceutical preparations and reagents containing these compounds
    Patent number: 7097854
    Abstract: The present invention relates to new amino alcohol derivatives, process for the production thereof and medicaments and reagents containing these compounds.
    Type: Grant
    Filed: January 31, 2002
    Date of Patent: August 29, 2006
    Assignee: MediGene Oncology GmbH
    Inventors: Walter-Gunar Friebe, Nikolaos Dimoudis, Uwe Michaelis, Bernhard Knipp
  • Amide derivatives
    Publication number: 20060116407
    Abstract: The present invention relates to the compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
    Type: Application
    Filed: November 15, 2005
    Publication date: June 1, 2006
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Eike Hoffmann, Thomas von Hirschheydt, Edgar Voss
  • Thioether derivatives
    Patent number: 7005526
    Abstract: Objects of the present invention are the compounds of formula (I) formula (I), their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above compounds in the control or prevention of illnesses such as cancer.
    Type: Grant
    Filed: May 18, 2005
    Date of Patent: February 28, 2006
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Thomas Friess, Lothar Kling, Ulrike Reiff, Edgar Voss
  • Novel benzylether derivatives
    Publication number: 20050267178
    Abstract: Objects of the present invention are the compounds of formula (I) their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
    Type: Application
    Filed: May 18, 2005
    Publication date: December 1, 2005
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Thomas Friess, Christian Geletneky, Guy Georges, Irene Kolm, Edgar Voss
  • NOVEL THIOETHER DERIVATIVES
    Publication number: 20050267179
    Abstract: Objects of the present invention are the compounds of formula (I) their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above compounds in the control or prevention of illnesses such as cancer.
    Type: Application
    Filed: May 18, 2005
    Publication date: December 1, 2005
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Thomas Friess, Lothar Kling, Ulrike Reiff, Edgar Voss
  • Novel diazine derivatives
    Publication number: 20050222228
    Abstract: The present invention provides compounds of formula (I): their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
    Type: Application
    Filed: March 31, 2005
    Publication date: October 6, 2005
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Wolfgang Jenni, Matthias Rueth, Edgar Voss
  • Novel ether derivatives
    Publication number: 20050209290
    Abstract: The present invention provides the compounds of formula (I) their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
    Type: Application
    Filed: March 17, 2005
    Publication date: September 22, 2005
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Thomas Friess, Ulrike Reiff, Edgar Voss
  • Novel oxidized thioether derivatives
    Publication number: 20050203064
    Abstract: The present invention provides the compounds of formula I their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
    Type: Application
    Filed: March 4, 2005
    Publication date: September 15, 2005
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Thomas Friess, Lothar Kling, Matthias Rueth, Edgar Voss
  • Novel pentafluorosulfanyl compounds
    Publication number: 20050197370
    Abstract: The present invention provides the compounds of formula I-A their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
    Type: Application
    Filed: March 4, 2005
    Publication date: September 8, 2005
    Inventors: Birgit Bossenmaier, Walter-Gunar Friebe, Guy Georges, Matthias Rueth, Edgar Voss