Patents by Inventor Walter Haefliger

Walter Haefliger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel 8.alpha.-acylaminoergolines
    Patent number: 5077298
    Abstract: Compounds of formula I ##STR1## wherein R.sub.1 is hydrogen or C.sub.1-4 alkyl, R.sub.2 is hydrogen, chlorine, bromine or methyl, R.sub.3 is C.sub.1-5 alkyl or C.sub.3-5 alkenyl and R.sub.4 is C.sub.3-7 alkyl; C.sub.3-7 cycloalkyl; adamantyl; or optionally substituted phenyl, having valuable pharmaceutical, and in particular LH- and PRL-secretion inhibiting as well as neuroleptic activity.
    Type: Grant
    Filed: July 2, 1990
    Date of Patent: December 31, 1991
    Assignee: Sandoz Ltd.
    Inventor: Walter Haefliger
  • 8.alpha.-acylaminoergoline, its preparation and pharmaceutical compositions containing it
    Patent number: 5075318
    Abstract: 8.alpha.-Acylaminoergoline useful in the treatment of psychotic disorders and Parkinson's disease.
    Type: Grant
    Filed: November 2, 1990
    Date of Patent: December 24, 1991
    Assignee: Sandoz Ltd.
    Inventor: Walter Haefliger, deceased
  • 2-substituted-8.alpha.-branched chain acylaminoergolines
    Patent number: 4950672
    Abstract: Compounds of the formula I ##STR1## wherein R.sub.1 is hydrogen or C.sub.1-4 alkyl, R.sub.2 is hydrogen, chlorine, bromine or methyl, R.sub.3 is C.sub.1-5 alkyl or C.sub.3-5 alkenyl and R.sub.4 is C.sub.3-7 alkyl; C.sub.3-7 cycloalkyl; adamantyl; or optionally substituted phenyl, having valuable pharmaceutical, and in particular LH- and PRL-secretion inhibiting as well as neuroleptic activity.
    Type: Grant
    Filed: February 27, 1989
    Date of Patent: August 21, 1990
    Assignee: Sandoz Ltd.
    Inventor: Walter Haefliger
  • 2,6-dimethyl-8.alpha.-pivaloylamino-9,10-didehydro-ergoline
    Patent number: 4791115
    Abstract: Compounds of formula I ##STR1## wherein R.sub.1 is hydrogen or C.sub.1-4 alkyl, R.sub.2 is hydrogen, chlorine, bromine or methyl, R.sub.3 is C.sub.1-5 alkyl or C.sub.3-5 alkenyl and R.sub.4 is C.sub.1-7 alkyl; C.sub.3-7 cycloalkyl; adamantyl; or optionally substituted phenyl, are useful as neuroleptic agents and PRL secretion inhibitors.
    Type: Grant
    Filed: January 12, 1987
    Date of Patent: December 13, 1988
    Assignee: Sandoz Ltd.
    Inventor: Walter Haefliger
  • Substituted-2,3-dihydrobenzofuran-2-ones
    Patent number: 4252817
    Abstract: This invention provides new compounds of the formula, ##STR1## wherein R.sub.1 is alkyl of 1 to 10 carbon atoms, cycloalkyl of 3 to 8 carbon atoms or phenyl,R.sub.2 is hydrogen or lower alkyl, andR.sub.3 is halogen, nitro, lower alkyl, methylthio, hydroxy, lower alkoxy, acyloxy or acylamino, with the proviso that when R.sub.3 is in the 5 position, and R.sub.1 and R.sub.3 are identical and signify a straight alkyl chain of 1 to 5 carbon atoms, R.sub.2 is lower alkyl,useful as anti-phlogistics.
    Type: Grant
    Filed: May 11, 1979
    Date of Patent: February 24, 1981
    Assignee: Sandoz Ltd.
    Inventors: Annemarie Closse, Walter Haefliger, Daniel Hauser
  • Phenyl- or cycloalkyl-benzo-oxacyclic compounds
    Patent number: 4232039
    Abstract: The invention provides compounds of formula I, ##STR1## wherein R.sub.1 is branched alkyl, cycloalkyl or phenyl,R.sub.2 is hydrogen, methyl or halogen,X--Y is --CHR.sub.3 CH.sub.2 --, --CR.sub.3 .dbd.CH-- or --(CH.sub.2).sub.4, andR.sub.3 is hydrogen or alkyl,useful, for example, in the treatment of oedemas, inflammation and arthritis.
    Type: Grant
    Filed: April 14, 1978
    Date of Patent: November 4, 1980
    Assignee: Sandoz Ltd.
    Inventors: Annemarie Closse, Walter Haefliger, Daniel Hauser
  • Organic compounds
    Patent number: 4013690
    Abstract: This invention provides compounds of formula I, ##STR1## wherein R.sub.1 is alkyl of 1 to 10 carbon atoms, cycloalkyl of 3 to 8 carbon atoms or phenyl, andR.sub.2 is hydrogen or alkyl of 1 to 4 carbon atoms,Useful as anti-phlogistics, anti-pyretics, analagesics and inhibitors of blood platelet aggregation.
    Type: Grant
    Filed: January 30, 1975
    Date of Patent: March 22, 1977
    Assignee: Sandoz Ltd.
    Inventors: Annemarie Closse, Walter Haefliger, Daniel Hauser