Abstract: This invention relates to compositions and methods for preventing oxidation of beneficial agents.

Abstract: Drug delivery systems and kits are provided that release an anesthetic, such as bupivacaine, over a short duration. Methods of administering and preparing such systems are also provided. Drug delivery systems include a short duration gel vehicle and an anesthetic dissolved or dispersed in the gel vehicle. The gel vehicle comprises a low molecular weight bioerodible, biocompatible polymer and a water-immiscible solvent in an amount effective to plasticize the polymer and form a gel with the polymer. In some instances, a component solvent is used along with the water-immiscible solvent. An efficacy ratio, which is one way to measure the efficacy of a delivery system, can be controlled based on, for example, the construction of the gel vehicle to achieve a desired release profile.

Abstract: Injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having a miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions have substantially improved the shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection.

Abstract: Injectable depot compositions are provided that include a bioerodible, biocompatible polymer, an aromatic alcohol having miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, and a beneficial agent. The composition may additionally contain an ester of an aromatic acid, or an aromatic ketone. The compositions are readily implanted beneath a patient's body surface by injection, as the aromatic alcohol not only facilitates solubilization of the polymer, but also acts as a thixotropic agent, substantially increasing the shear thinning behavior of the composition.

Abstract: The arrangement contains a carrier (4) which is mounted in a drive shaft (1) which is formed as a hollow shaft with holes (10) which are arranged in a radial plane, two switching tappets (5) which are displaceably arranged in the holes, two control members (7) which can be brought into operative engagement with the switching tappets, means (8) for the actuation of the control members and two resetting elements (9) for the control members (7). The control members are displaceable in the carrier with respect to the drive shaft into a first position in order to switch the coupling apparatus into a drive position and into a second position in order to switch the coupling apparatus into an idling position. The resetting members (9) are arranged inside the drive shaft (1) in order to displace the control members (7) into the second position. With this arrangement the resetting of the control members is ensured.

Abstract: A weft thread selecting and supplying device has an electronically controllable electric motor (2) with a drive wheel (4) and a guide wheel (5), and a gear belt (6) which loops around these wheels. Thread suppliers (7, 7a) are connected to both longitudinal runs of the gear belt (6) and staggered relative to each other so that one thread supplier (7a) is in a ready position (B) and the other is in a transfer position (U). The thread suppliers (7, 7a) have thread eyes (9) through which the weft threads (17, 17a) run. In the ready position (B) the weft thread (14a) is outside of the take along range of a weft thread insertion gripper head (15). In the transfer position (U) the weft thread (17) is in a position to be gripped by the gripper head (15). The electric motor (2) rotates the drive wheel (4) in accordance with the pattern being woven and in synchronism with the weaving cycle, whereby the drive wheel (4) moves the gear belt (6).

Abstract: A control device for textile machines, in particular dobbies, has two magnet yokes with associated permanent magnets and an electromagnet, as well as an appropriately built magnet armature held in a first or second end position by the permanent magnet flux. When a current control pulse is applied to the electromagnet, however, the armature suddenly moves to the opposite end position, where it is again held until the next current control pulse moves it to the other end position. Only a very short current pulse is necessary to make the magnet armature change position. The resulting energy impulse is very intense and allows the holding and switching mechanical elements of dobbies to be directly controlled.

Abstract: A dobby includes a needle mechanism having a reading needle, the head of which, during reading of a nonperforated location on a pattern card, engages a pawl and, during reading of a hole in the card, releases the pawl to permit the pawl, under the force of a spring, to tilt about an axle and in this manner to have a surface thereof disposed in front of an edge of a key-shifting gate. During the operating movement of the axle, the pawl pushes the key-shifting gate, which slides in rectilinear guides, wherein a key is carried along by a cam which encircles the opening for the shaft 1. The key is radially movably supported on the eccentric ring and engages one of two openings on the connecting rod, which results in a standstill of the heddle frame, or engages one of two grooves in the drive shaft. In the latter case, the drive shaft carries the key and the eccentric ring along as it rotates and moves the connecting rod, which triggers a movement of the heddle frame.

Abstract: A weaving machine is operationally connected to a shed-forming machine which includes a drive shaft and a braking mechanism. The latter includes a braking disk which is axially slidably supported on the drive shaft of the shed-forming machine. The braking disk can, during movement thereof, come into frictional engagement with a stationary counterpart. In an alternative embodiment, a modified pick-finding device is used as a brake. In the case of a halt of the weaving machine which is to be carried out quickly, for example during a thread break, the braking mechanism of the shed-forming machine is actuated to relieve the braking mechanism of the weaving machine, and thus no great braking action need be transmitted through the drive for the shed-forming machine.

Abstract: A pick-finding mechanism is arranged between a weaving machine and a shed-forming machine. A sleeve of a gear sits rotatably on a shaft, which gear is driven by the weaving machine. A single-tooth coupling can transmit forces from the gear to a sliding sleeve which is secured by a key to the shaft and can be moved axially of the shaft by a switch lever. The shaft can be driven through a multiple-tooth coupling by a motor and a drive gear. The switch lever serves to couple and uncouple the couplings.To find the pick, the single-tooth coupling is disengaged and the multi-tooth coupling is engaged. The weaving machine and dobby can be driven together in phase and in both directions by the motor at slow speed, by simultaneously engaging both couplings. This slow or creeping speed permits observation of the functioning and stopping of the machines in any desired position at any time.

Abstract: A method and apparatus for synchronizing all heddle frames of a weaving machine which are operated by a punched-card-controlled dobby. The pattern card cylinder or the reading needles are moved to positions in which during a read, all the reading needles simultaneously engage the pattern card webs between the control points or the holes of the pattern card. Through this, the heddle frames are moved to the lower shed position by further operation of the dobby.In a preferred embodiment, the card cylinder is stopped in the center of the indexing movement effected by the driving projection of the drive shaft. The driving projection is laterally uncoupled from a ratchet gear by a hand lever and, simultaneously, further movement of the ratchet gear is prevented by the engagement of a locking member in a tooth space of the ratchet gear.

Abstract: An apparatus for controlling a dobby in which reading needles read a punch card and each needle influences the movement of a respective heddle frame. Two outer disks having annular toothed portions arranged on the axial facing sides thereof which face one another are secured on the shaft of a punch card drive cylinder. The teeth of the toothed portions are angularly offset by one-half the tooth pitch. Between the two outer disks, and freely rotatably supported on the shaft is a central disk with annular toothed portions on the axially facing sides thereof which are also offset by one-half the tooth pitch. A movable guide member for the reading needles is secured on and driven reciprocally by the central disk. Upon indexing the pattern card for one pick, the toothed portion of one outer disk moves the central disk toward the second outer disk and effects engagement of the facing toothed portions on the central disk and the second outer disk.

Abstract: To move pile heddle frames between three or rather four shed positions, a four-position rocking lever is arranged between two adjacent heddle frame lifting units and the rocking lever controlling the heddle frame. The free end of the first lifting unit rocking lever is a hinge point for the four-position rocking lever and the free end of the second lifting unit rocking lever is a hinge point for a connecting bar extending to the four-position rocking lever. To reduce wild movements of the heddle frame, no loaded shafts are provided in the power-transmitting path from the lifting unit to the heddle frame, aside from shafts supporting the lifting units and the rocker arm of the heddle frame.

Abstract: A reading and lifting device has a force amplifying bar which can be reciprocated vertically and is driven positively, and a reading needle is slidably supported therein. A pattern card with nonperforated and perforated points is provided below the force amplifying bar. When the needle hits a nonperforated point, the needle is moved back into the force amplifying bar. In one embodiment, the needle slides with its head on a surface which effects a swivelling of a lock member. Through this, an end of the lock member comes to lie in front of an offset portion of a control arm. The force amplifying bar during its downward movement then carries the control arm along against the force of a spring. The device facilitates the sensitive reading of a pattern card and the forceful passing on of the control information read.

Abstract: A dobby with a mechanical reading device for a control card having perforated and nonperforated portions therein according to a pattern. The reading needle of the reading device of the pattern card has yielding elements for the purpose of reducing the impact force of the reading needle onto the pattern card.

Abstract: There is provided a device for either advancing or retracting the relative movement of a dobby with respect to the heddles of a weaving machine or with respect to any one or selected ones of such heddles. Thus, the shed-intersection point within said weaving machine may be advanced or retarded with respect to the dobby with resulting desirable modifications in the finished fabric. Same is accomplished by driving both the dobby and the heddle or heddles through a pair of levers and including a device by which the angle between said levers can be modified in order to modify the operational phase angle between such dobby and such heddle or heddles.