Patents by Inventor Walter Nickel

Walter Nickel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11786909
    Abstract: A method of adapting a centrifugal machine that is a dual asymmetric centrifugal mixer or a planetary mill, used for mixing materials, for grinding one or more materials; it includes positioning in a container of the machine, non-spherical grinding media, and securing a lid on the opening of the container, wherein the bases of the units of the non-spherical grinding media are prevented from toppling by having a shortest distance between the center of mass of the unit of non-spherical grinding media and a base be less than half of the width of the base; or securing the lid sufficiently near the top of the units of the non-spherical grinding media such that when a unit of the non-spherical grinding media tilts, the unit of the non-spherical grinding media contacts the lid, the lid acting as an obstacle preventing the unit of the non-spherical grinding media from toppling.
    Type: Grant
    Filed: December 12, 2022
    Date of Patent: October 17, 2023
    Inventor: Christopher Walter Nickels
  • Publication number: 20230107564
    Abstract: A method of adapting a centrifugal machine that is a dual asymmetric centrifugal mixer or a planetary mill, used for mixing materials, for grinding one or more materials; it includes positioning in a container of the machine, non-spherical grinding media, and securing a lid on the opening of the container, wherein the bases of the units of the non-spherical grinding media are prevented from toppling by having a shortest distance between the center of mass of the unit of non-spherical grinding media and a base be less than half of the width of the base; or securing the lid sufficiently near the top of the units of the non-spherical grinding media such that when a unit of the non-spherical grinding media tilts, the unit of the non-spherical grinding media contacts the lid, the lid acting as an obstacle preventing the unit of the non-spherical grinding media from toppling.
    Type: Application
    Filed: December 12, 2022
    Publication date: April 6, 2023
    Inventor: Christopher Walter NICKELS
  • Publication number: 20210130786
    Abstract: A method for the identification of compounds modulating the biological activity of FGF2, the method comprising the use of target cells sensitive to the presence of FGF2 by obstructing proliferation, wherein the target cells constitutively express a first reporter in- the nucleus of living target cells.
    Type: Application
    Filed: January 7, 2021
    Publication date: May 6, 2021
    Applicant: Universitaet Heidelberg
    Inventor: Walter Nickel
  • Patent number: 10842793
    Abstract: The present invention relates to compounds that have the capability of inhibiting the secretion of fibroblast growth factor 2 (FGF2) by tumor cells, as well as uses of said compound in medicine, in particular in the prevention and/or treatment of cancerous or inflammatory diseases.
    Type: Grant
    Filed: February 7, 2017
    Date of Patent: November 24, 2020
    Assignees: Universitat Heidelberg, European Molecular Biology Laboratory
    Inventors: Walter Nickel, Joe Lewis
  • Publication number: 20190307752
    Abstract: The present invention relates to compounds that have the capability of inhibiting the secretion of fibroblast growth factor 2 (FGF2) by tumor cells, as well as uses of said compound in medicine, in particular in the prevention and/or treatment of cancerous or inflammatory diseases.
    Type: Application
    Filed: February 7, 2017
    Publication date: October 10, 2019
    Inventors: Walter Nickel, Joe Lewis
  • Patent number: 10099203
    Abstract: A method for the preparation of a metal-organic compound is provided. This method comprises the steps of (a) providing at least one metal precursor, (b) providing at least one bridging organic ligand, and (c) exposing together the metal precursor and the ligand to liquid CO2 or supercritical CO2 as a reaction medium, thereby producing said metal-organic compound.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: October 16, 2018
    Assignee: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Tomislav Friscic, Chao-Jun Li, Simon Girard, Cristina Mottillo, Christopher Walter Nickels
  • Publication number: 20180043330
    Abstract: A method for the preparation of a metal-organic compound is provided. This method comprises the steps of (a) providing at least one metal precursor, (b) providing at least one bridging organic ligand, and (c) exposing together the metal precursor and the ligand to liquid CO2 or supercritical CO2 as a reaction medium, thereby producing said metal-organic compound.
    Type: Application
    Filed: February 22, 2016
    Publication date: February 15, 2018
    Inventors: Tomislav FRISCIC, Chao-Jun LI, Simon GIRARD, Cristina MOTTILLO, Christopher Walter NICKELS
  • Publication number: 20170241980
    Abstract: A method for the identification of compounds modulating the biological activity of FGF2, the method comprising the use of target cells sensitive to the presence of FGF2 by obstructing proliferation, wherein the target cells constitutively express a first reporter in the nucleus of living target cells.
    Type: Application
    Filed: October 12, 2015
    Publication date: August 24, 2017
    Inventor: Walter Nickel
  • Patent number: 4420456
    Abstract: A mounting for power conductor and instrument lead penetrations in nuclear reactors provides a device that is simple, compact and at the same time easily installed, repaired or replaced. The mounting comprises a cylinder like, stepped housing which is to pass through the pressure vessel wall of the nuclear reactor and house at least one and preferably a plurality of electrical conductors.
    Type: Grant
    Filed: April 23, 1981
    Date of Patent: December 13, 1983
    Assignee: Hochtemperatur-Reaktorbau GmbH
    Inventors: Walter Nickel, Josef Schoening, Hans-Georg Schwiers
  • Patent number: 4337517
    Abstract: A new microprocessor controlled digital multimeter offers significant advantages to the user. Automatic calibration allows a new reference IC board to be inserted and because of such calibration the multimeter is instantly ready for use.
    Type: Grant
    Filed: October 22, 1979
    Date of Patent: June 29, 1982
    Assignee: Systron Donner Corporation
    Inventors: Walter Nickel, Zoltan Tarczy-Hornoch
  • Patent number: 4200933
    Abstract: A new microprocessor controlled digital multimeter offers significant advantages to the user. Automatic calibration and correction routines ensure long term stability and simplify maintenance; self diagnostics greatly help troubleshooting and even warn of impending failures; software implementation of logic design simplifies hardware, improves reliability and adds capabilities such as fast auto ranging and software I/O control; the ability to process data permits averaging, linearization and normalization of input measurements, minimum/maximum storage and limit detection.
    Type: Grant
    Filed: September 16, 1976
    Date of Patent: April 29, 1980
    Assignee: Systron-Donner Corporation
    Inventors: Walter Nickel, Zoltan Tarczy-Hornoch