Patents by Inventor Walter Sebald

Walter Sebald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140148387
    Abstract: The present invention provides a freeze-dried preparation obtained by dissolving an active type human bone morphogenetic protein-2 homodimer added with an alanine residue to the N-terminus in a strong acid solution and freeze-drying the solution, a production method of the preparation, and a kit for regeneration and treatment of bone, which contains the preparation.
    Type: Application
    Filed: September 1, 2010
    Publication date: May 29, 2014
    Inventors: Masahiro Nagaya, Kazushige Sugama, Walter Sebald
  • Patent number: 7786080
    Abstract: The present invention is related to a mutein of a bone morphogenetic protein, whereby the mutein comprises an amino acid substitution compared to the wildtype of the bone morphogenetic protein at the amino acid position corresponding to amino acid position 51 of human BMP-2.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: August 31, 2010
    Assignee: Julius-Maximilians-Universitat Wurzburg
    Inventors: Thomas Muller, Walter Sebald
  • Publication number: 20070293425
    Abstract: The present invention is related to a mutein of a bone morphogenetic protein, whereby the mutein comprises an amino acid substitution compared to the wildtype of the bone morphogenetic protein at the amino acid position corresponding to amino acid position 51 of human BMP-2.
    Type: Application
    Filed: March 4, 2005
    Publication date: December 20, 2007
    Inventors: Thomas Muller, Walter Sebald
  • Patent number: 7253254
    Abstract: The invention pertains to polypeptide variants with increased heparin-binding ability. Increased heparin-binding ability is achieved by addition, insertion, and/or substitution of an amino acid sequence X1X2X3X4X5X6 (SEQ ID NO. 1 or NO.2). Polypeptide variants according to the invention are particularly suited for stimulation of chondrogenesis, osteogenesis, and wound healing. The invention also pertains to amino acid molecules that encode said polypeptide variants, host cells containing said nucleic acid molecules, and processes for producing the polypeptide variants.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: August 7, 2007
    Assignee: Osteopharma Inc.
    Inventor: Walter Sebald
  • Patent number: 6685932
    Abstract: The design of antagonists of 4-helix bundle cytokine specific receptors, mimetic peptides that are able to act as such antagonists and their use as pharmaceutical agents is disclosed.
    Type: Grant
    Filed: May 12, 2000
    Date of Patent: February 3, 2004
    Assignee: Europaisches Laboratorium Molekularbiologie
    Inventors: Helena Domingues, David Cregut, Walter Sebald, Hartmut Oschkinat, Luis Serrano
  • Patent number: 6130318
    Abstract: The present invention relates to novel hIL-4 mutant proteins, to processes for preparing them, and to their use as medicaments, in particular in overshooting, falsely regulated immune reactions and autoimmune diseases.
    Type: Grant
    Filed: December 19, 1996
    Date of Patent: October 10, 2000
    Assignee: Bayer Aktiengellschaft
    Inventors: Hanno Wild, Rudolf Hanko, Michael Dorschug, Hans-Dietrich Horlein, Jurgen Beunink, Heiner Apeler, Hermann Wehlmann, Walter Sebald
  • Patent number: 5723118
    Abstract: The invention relates to therapeutic agents which are antagonists or partial agonists of human interleukin 4, or contain these antagonists or partial agonists, to mutant hIL-4 proteins and to processes for their preparation.
    Type: Grant
    Filed: May 6, 1994
    Date of Patent: March 3, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventor: Walter Sebald
  • Patent number: 4826764
    Abstract: The invention concerns the intercistronic DNA sequence of the atp operon of Escherichia coli for the subunit c of the ATP synthase, a DNA structure and an expression vector which are characterized by the said intercistronic DNA sequence, and a process for the production of proteins using the same. The DNA sequence enhances the rate of synthesis of the proteins.
    Type: Grant
    Filed: July 17, 1985
    Date of Patent: May 2, 1989
    Assignee: Gesellschaft fur Biotechnologische Forschung mbH
    Inventor: Walter Sebald
  • Patent number: 4089233
    Abstract: An automobile mirror device comprises a mirror mounted in a carrier which is connected by a universal joint to a base. A threaded spindle, driven by an electric motor, engages a split nut held by a spring steel stirrup pivotally connected to the carrier. When the mirror is tilted by rotation of the spindle to either of its end positions, the thread will disengage the nut by forcing apart the parts of the nut.
    Type: Grant
    Filed: August 19, 1976
    Date of Patent: May 16, 1978
    Assignee: Gebr. Marklin & Cie. GmbH
    Inventor: Walter Sebald