Abstract: A running board assembly is provided for a motor vehicle. The running board assembly includes a mounting bracket adapted to be fixedly secured to the motor vehicle. The running board assembly also includes a step having a stepping surface. A link includes an upper end coupled to the mounting bracket and an opposing lower end coupled to the step. A light source is fixedly mounted to the link for illuminating the stepping surface to allow users to locate the step.

Abstract: The present invention relates to new beta-agonists of general formula (I) wherein the groups R1 to R4 have the meanings given in the claims and specification, the tautomers, racemates, enantiomers, diastereomers, solvates, hydrates, mixtures thereof, the prodrugs thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, methods of preparing these compounds and their use as pharmaceutical compositions.

Abstract: The invention relates to a novel 3,9-diazabicyclo[3.3.1]nonene derivative and the enantiomers thereof and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing at least one compound of formula (I) or (I?) and especially their use as inhibitors of renin.

Abstract: The present invention generally relates to light sources that have variable and adjustable luminous intensities. According to certain preferred embodiments of the invention, devices are provided that generally comprise (1) a conductive elastomeric material that is located between a first and second conductive surface; (2) a power source operably connected to the first conductive surface; and (3) a light source operably connected to the second conductive surface. In such embodiments, the conductive elastomeric material comprises an electrical resistance that decreases when the material is compressed or contacts a greater surface area of the first or second conductive surface. By modulating the compression state of the elastomeric material (and, therefore, the ohmic resistance thereof), the amount of electrical power transmitted from the power source to the light source is controlled, which in turn affects the luminous intensity of the light emitted therefrom.

Abstract: A line narrowing method and module for a narrow band DUV high power high repetition rate gas discharge laser producing output laser light pulse beam pulses in bursts of pulses, the module having a nominal optical path are disclosed which may comprise: a dispersive center wavelength selection optic moveably mounted within an optical path of the line narrowing module, selecting at least one center wavelength for each pulse determined at least in part by the angle of incidence of the laser light pulse beam containing the respective pulse on the dispersive wavelength selection optic; a first tuning mechanism operative in part to select the angle of incidence of the laser light pulse beam containing the respective pulse upon the dispersive center wavelength selection optic, by selecting an angle of transmission of the laser light pulse beam containing the pulse toward the dispersive center wavelength selection optic; a second tuning mechanism operative in part to select the angle of incidence of the laser light pu

Abstract: A mailbox has an aerodynamic shape that deflects snow thrown by the snowplow and an anchoring system that permits stable anchoring of the mailbox, yet easy replacement in the event such replacement is required.

Abstract: The present invention relates to a novel human K+ ion channel, to nucleic acid molecules encoding the same and to vectors comprising said nucleic acid molecules. The invention additionally relates to antibodies specifically directed to the novel K+ ion channel and to pharmaceutical compositions and diagnostic kits containing at least one of the above-mentioned components. Furthermore, the present invention relates to methods of treating a disease caused by malfunction of the polypeptide of the present invention or by the (over)expression of the nucleic acid molecule of the invention comprising administering an inhibitor of said (over)expression or of ion channel function or an inhibitor abolishing said malfunction to a patient in need thereof. Methods of devising drugs for treating or preventing the above-mentioned disease, methods of inhibiting cell proliferation and methods of prognosing cancer are additional embodiments comprised by the present invention.

Abstract: A pharmaceutical composition comprising a compound of formula (1) in polymorphic crystalline Form A: together with a pharmaceutically acceptable carrier or excipient, wherein the compound of formula (1) is present in polymorphic Form A (see, e.g., FIG. 6) substantially free of other polymorphic forms.

Abstract: A billing method and billing system to determine usage fees which are charged to the user of a digital telecommunications network, whereby a usage fee charged for a connection is determined prior to establishing this connection from statistical characteristics of previous connections of the user, is described. Usage fees are determined from a dynamic client profile, derived from one or multiple random variables of previous connections of the user, which is stored in memory and re-derived after each new customer connection. In a simple variant, the client profile contains a value proportional to the average price per connection or to the average duration of a connection of the user. The random variables used to derive the client profile include, for example, the connection duration, the time of day, the day of the week, and/or geographic characteristics of previous connections.

Abstract: Disclosed is a method and apparatus for an alignment system for use in a data storage system for enabling numerous contact cycles between two surfaces in a robust manner. The system includes a first and a second surface each having at least two contact zones. Each of the contact zones comprise either a conductive spring or a conductive pad. Each of the conductive springs is adapted to engage a corresponding conductive pad, wherein the engaging location on the pad is substantially flat, to form at least one closed circuit when the first and the second surfaces are aligned and are in contact. A continuity confirmation device can further be used to confirm the closed circuit.

Abstract: It has now been found that certain novel N-(substituted aryl)-4-(disubstituted methyl)piperidine and pyridine derivatives have provided unexpected insecticidal activity. These compounds are represented by formula (I): wherein m, n, q, r, and s are independently selected from 0 or 1; and p is 0, 1, 2, or 3; A is CH or N; and B, D, E, R, R1, R2, R3, R4, R5, R6, R7 and R8 are fully described herein. In addition, compositions comprising an insecticidally effective amount of at least one compound of formula I, and optionally, an effective amount of at least one of a second compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present.

Abstract: A system and method are used to increase alignment accuracy of feature patterns through detection of alignment patterns on both a surface layer and at least one below surface layers of an object. Visible light is used to detect alignment patterns on the surface layer and infrared light is used to detect patterns one layers below the surface. For example, reflected visible light and transmitted infrared light are co-focused onto detector after impinging on respective alignment patterns. The co-focused light is then used to determine proper alignment of the object for subsequent pattern features. This substantially increases accuracy of alignment of pattern features between layers, as compared to conventional systems.

Abstract: Time-scaled, sound signals (i.e. sounds output at differing speeds) are generated by mixing weighted time-and frequency-domain processed signals, the former signal generally representing speech-based signals while the latter representing music-based signals. The weights applied to each type of signal may be determined by a scaling factor, which in turn is related to the desired speed at which a listener desires to hear a sound signal. In one example of the invention, only stationary signal portions of an input sound signal are used to generate time-scaled processed signals. An adaptive frame-size may also be used to pre-process the separate signals prior to being weighted, which at least decreases the amount of unwanted reverberative sound qualities in a resulting sound signal. Together, techniques envisioned by the present invention produce improved, speed adjusted sound signals.

Abstract: Embodiments of the present invention provide an integrated methodology that simplifies upgrade choices for complex computer products through the use of automation and integration of product monitoring and business applications with, for example, web based capabilities. Historical information for computer systems is collected and transmitted to a remote support system. Over time, sufficient historical data provides a historical view of the systems indicative of usage and facilitating the choice of product enhancements, upgrades and customization. Further, this historical view may be integrated with the advances in the product that are kept by the remote support system as well as with the performance requirements of third party application providers.

Abstract: Various configurations for scatter reduction and control are provided for CT imaging. These configurations include an imaging system having a stationary detector extending generally around a portion of an imaging volume and a distributed X-ray source placed proximal to the stationary detector for radiating an X-ray beam toward the stationary detector. A scatter control system is further provided that is configured to adaptively operate in cooperation with the stationary detector and the distributed X-ray source to focally align collimator septa contained therein to the X-ray beam at a given focal point and to provide X-ray beam scatter control.

Abstract: The present invention relates to nucleic acid molecules encoding enzymes which are involved in the starch synthesis in plants. These enzymes are starch synthases from wheat. The invention further relates to vectors and host cells containing said nucleic acid molecules, in particular transformed plant cells and plants regenerated from these cells, which exhibit an increased or a reduced activity of the described starch synthases.

Abstract: The present invention relates to a novel human K+ ion channel, to nucleic acid molecules encoding the same and to vectors comprising said nucleic acid molecules. The invention additionally relates to antibodies specifically directed to the novel K+ ion channel and to pharmaceutical compositions and diagnostic kits containing at least one of the above-mentioned components. Furthermore, the present invention relates to methods of treating a disease caused by malfunction of the polypeptide of the present invention or by the (over)expression of the nucleic acid molecule of the invention comprising administering an inhibitor of said (over)expression or of ion channel function or an inhibitor abolishing said malfunction to a patient in need thereof. Methods of devising drugs for treating or preventing the above-mentioned disease, methods of inhibiting cell proliferation and methods of prognosing cancer are additional embodiments comprised by the present invention.

Abstract: In one aspect, the invention is the system for assessing a navigation augmentation environment. The system includes a reference station for receiving messages from a satellite. The reference station has a known position. The system also includes a simulator for simulating an augmentation system by determining corrections based on the messages received and the known position of the reference station. The system further includes a monitoring system to render the corrections to a user in a form enabling determination of the usability of the augmentation system in the navigation augmentation environment.

Abstract: The invention relates to an axial piston machine (1) comprising a housing (2) in which a drive disk (7) and a cylinder block (12) axially disposed next to it are received so as to be rotatable relative to each other about longitudinal center axes (11, 13). These axes run obliquely at an angle (W1) relative to each other in an oblique axis plane (E). A cam disk (18) is disposed on the front of the cylinder block (12) facing away from the drive disk (17) and is supported on the housing (2) by means of a positioning device (19) with positively engaging positioning elements (19a, 19b). A guide element (21) having a guide center axis (22) running coaxially to the longitudinal center axis (13) of the cylinder block (12) is disposed on the side facing the cylinder block (12).