Abstract: Methods for making prodrugs of treprostinil and treprostinil derivatives are provided. Specifically, methods are provided herein for producing prostacyclin compounds comprising treprostinil covalently linked to a linear C5-C18 alkyl, branched C5-C18 alkyl, linear C2-C18 alkenyl, branched C3-C18 alkenyl, aryl, aryl-C1-C18 alkyl or an amino acid or a peptide (e.g., dipeptide, tripeptide, tetrapeptide). The linkage, in one embodiment, is via an amide or ester bond. Prostacyclin compounds provided herein can also include at least one hydrogen atom substituted with at least one deuterium atom. The compounds provided herein can be used to treat pulmonary hypertension (e.g., pulmonary arterial hypertension) and portopulmonary hypertension.

Abstract: A novel and useful quantum computing machine architecture that includes a classic computing core as well as a quantum computing core. A programmable pattern generator executes sequences of instructions that control the quantum core. In accordance with the sequences, a pulse generator functions to generate the control signals that are input to the quantum core to perform quantum operations. A partial readout of the quantum state in the quantum core is generated that is subsequently re-injected back into the quantum core to extend decoherence time. Access gates control movement of quantum particles in the quantum core. Errors are corrected from the partial readout before being re-injected back into the quantum core. Internal and external calibration loops calculate error syndromes and calibrate the control pulses input to the quantum core.

Abstract: In one embodiment, a software agent profiler process attaches to an application and a primary instrumentation interface for the application, and discovers one or more software agents associated with the application. The software agent profiler process may then launch the one or more software agents within an encapsulated container environment of the software agent profiler process by configuring each of the one or more software agents, respectively, to point to a proxy instrumentation interface of the software agent profiler process instead of the primary instrumentation interface for the application. As such, the software agent profiler process may receive calls from the one or more software agents on the proxy instrumentation interface of the software agent profiler process, and can manage the calls from the one or more application agents prior to the calls being passed to the primary instrumentation interface for the application.

Abstract: A fin block is provided for a calibrating device for the calibrating of an extruded profile. The fin block includes a fin structure, which has a plurality of fins which are spaced apart from one another by grooves and are arranged in longitudinal direction of the fin block, wherein the fins of the fin structure have a variable dimension in longitudinal direction of the fin block. Further, there is provided a method for the production of the above-mentioned fin block and a calibrating device, which includes a plurality of the above-mentioned fin blocks. Furthermore, there is provided a system for the additive manufacture of the above-mentioned fin block, a corresponding computer program and corresponding data set.

Abstract: A method, system and apparatus are disclosed for a network node configured to communicate with a wireless device (WD). In some embodiments, the network node includes processing circuitry configured to cause the network node to determine delay offset information based at least in part on a common distance for a cell, the delay offset information indicating a common temporal delay offset and transmit the delay offset information to the WD in at least one of a system information block, SIB, and a radio resource control, RRC, message. In some embodiments, a wireless device includes processing circuitry configured to cause the wireless device to receive delay offset information in at least one of a system information block, SIB, and a radio resource control, RRC, message, the delay offset information being based at least in part on a common distance and the delay offset information indicating a common temporal delay offset.

Abstract: Various implementations disclosed herein include devices, systems, and methods that obtain information from a first electronic device (e.g., to improve interactions for a CGR environment). In some implementations at a second electronic device having a processor, event camera data is obtained corresponding to modulated light (e.g., light including an information signal in its modulation) emitted by an optical source on the first electronic device and received at an event camera. The second electronic device is able to identify information from the first electronic device based on detecting a modulation pattern of the modulated light based on the event camera data. In some implementations, second electronic device is the same electronic device that has the event camera (e.g., laptop) or a different electronic device that receives the event data (e.g., a server receiving the event data from a laptop computer).

Abstract: An exemplary power system utilizes turbines configured within a water intake conduit to the desalination processor to produce power for the desalination processor. Water intakes are configured to provide a natural flow of water to the desalination processor though hydrostatic pressure. One or more turbines coupled with the water intake conduits are driven and produce power for the system. The desalination processor incorporates Graphene filters to and may include a structured water system to increase the H3O2 concentration of the water prior to Graphene filters. Discharge water may be pumped back into the body of water but be separated from the intakes. A secondary power source, such as a renewable power source, may be used to produce supplemental power for the system. Power produced may be provided to a secondary outlet, such as a power grid, all above and/or underground.

Abstract: A tree stand assembly includes a platform that has a front edge for engaging a tree. A post is attached to the platform adjacent to the front edge and extends upwardly therefrom. A bracket is attached to a front side of the post and has a top side, a bottom side and a perimeter surface extending between the top and bottom sides. The perimeter surface includes a front surface, a rear surface, a first lateral surface and a second lateral surface. The front surface has a plurality of teeth therein extending forward of the bracket to engage a tree. The rear surface includes a central section and a pair of outer sections positioned on opposite sides of the central section. The outer sections extend away from the front surface and the central section toward an associated one of the first and second lateral surfaces.

Abstract: A method of pulse power drilling in a subterranean formation may comprise providing a drilling fluid comprising an oil external phase, an internal phase, and a hydrolysis reactant compound for reaction with water. The method may also comprise passing an electric current through the subterranean formation to extend a wellbore in the subterranean formation while circulating the drilling fluid through the wellbore.

Abstract: An inkjet printing system with a droplet measurement apparatus is described herein. The droplet measurement apparatus has a light source with a collimating optical system, an imaging device disposed along an optical path of the collimating optical system, and a droplet illumination zone in the optical path of the collimating optical system, the droplet illumination zone having a varying droplet illumination location, wherein the light source, the imaging device, or both are adjustable to place a focal plane of the imaging device at the droplet illumination location. The droplet measurement apparatus is structured to accommodate at least a portion of a dispenser of the printing system within the droplet illumination zone.

Abstract: Method for the production of polyoxazolidinone compounds, comprising the reaction of at least one biscarbamate compound (A) with at least one bisepoxide compound (B) in the presence of at least one base (D), at least one Lewis acid catalyst (E), and optionally at least one compound (C), wherein the compound (C) comprising a mono-carbamate group, a mono-isocyanate group and/or a mono-epoxide group, and wherein the base (D) having a pKb-value of ?9. The invention is also related to the resulting polyoxazolidinone compounds.

Abstract: A light dimming system includes one or more lights and includes a local light controller that includes a dimming controller and a processing circuit, the dimming controller configured to provide an output to the one or more light drivers. One or more electronic processors are configured to receive a dimming input value indicating a desired dimming level for the one or more lights. The processors are further configured to determine a configuration of the one or more light drivers, wherein the configuration defines whether the one or more light drivers utilize a non-linear dimming curve or a linear dimming curve, and provides the dimming controller a dimming level to output a dimming control signal to the one or more light drivers equivalent to the received dimming input value based on a non-linear or linear calculation.

Abstract: A software platform includes emergency event processing functionality for detecting and mapping emergency event occurrences. The emergency event processing includes call path processing for concurrently routing an emergency call from a device registered with the software platform for a customer thereof to a public safety access point and to a monitoring device of the customer. The concurrent routing enables an operator of the monitoring device to join the emergency call, for example, by monitoring the call to determine how to notify other operators of the customer of the subject emergency event or by participating in the call to assist in the emergency event response. The concurrent routing may further automate, and therefore expedite, the signaling of an emergency event to others at the location of the emergency event, such as to prevent further risk of harm.

Abstract: A modular plug-in bus wiring system for electrical connections. The system includes an adapter module, the adapter module including at least a housing wherein the housing includes a front side containing at least an electrical connector, a back side, an upper end, a lower end, and at least a receptacle. The system includes at least a plug configured to insert in the at least a receptacle wherein the at least a plug is connected to at least a cable that includes at least an electrically conductive wire. The at least a plug includes a ventral surface, a dorsal surface, a first side and a second side.

Abstract: An electric drive motorcycle (100), allows an effective arrangement of the battery unit thereof, optimizing the available space, and comprises: a front portion comprising one or more front wheels (103) and a handlebar (104); a rear portion comprising a saddle (101), a shell body (107) arranged below said saddle (101), and a rear wheel (105) arranged below said shell body (105); an intermediate portion (108) extending as a connection between said front portion and said rear portion; an electric drive unit (8) connected to said rear wheel by means of a transmission unit; and a power supply unit feeding said electric drive unit and comprising at least a battery unit (15; 115), wherein said battery unit (15; 115) is shaped so as to have a polyhedral shape comprising at least a first side (28) tilted with respect to a vertical plane orthogonal to the front-rear direction of the motorcycle (100), wherein the battery unit (115) occupies a position below a helmet carrying compartment (11) arranged below the saddle (1

Abstract: The invention is concerned with a method for performing a calibration procedure for calibrating an eye tracking device (12), wherein a stimulus object (S) is displayed within a certain display area (22), such that the stimulus object (S) is at least temporarily moving along a defined trajectory (26) and images of at least one eye (16) of at least one user (18) are captured during the displaying of the stimulus object (S). Based on the captured images gaze data are provided and in dependency of the gaze data gaze points (P) of the at least one eye (16) of the user (18) with respect to the display area (22) are determined. Further, at least one calibration parameter (a1; a2; a3; a4; a5; a6; a7; a8; a9; a10; a11; a12; a13; a14; ?; R; K; a; b; r) of at least one predefined calibration model (M, M1, M2, M3, M4, M5, M6) is determined in dependency of a first analysis at least of positions of at least part of the respective gaze points (P) with regard to the defined trajectory (26) of the stimulus object (S).

Abstract: The present invention provides a light emitting device comprising a first light emitting portion that emits white light at a color temperature of 6000K or more and a second light emitting portion that emits white light at a color temperature of 3000K or less, which include light emitting diode chips and phosphors and are independently driven. The present invention has an advantage in that a light emitting device can be diversely applied in a desired atmosphere and use by realizing white light with different light spectrums and color temperatures. Particularly, the present invention has the effect on health by adjusting the wavelength of light or the color temperature according to the circadian rhythm of humans.

Abstract: A wireless device (400), a higher layer node (404) and methods therein, for handling measurement reporting in a wireless network as performed by the wireless device (400). The wireless device (400) detects (4:1) a coverage object being a cell or a beam not contained in a predefined first list of coverage objects for which the wireless device (400) is required to send measurement reports to a lower layer node (402) operable according to at least one of layer 1 and layer 2. The wireless device (400) then measures a radio signal of the coverage object where the measured radio signal fulfils a predefined event condition, and sends (4:2B) a measurement report of said measuring to a higher layer node (404) operable according to one or more layers above layer 1 and layer 2.

Abstract: A molding process includes the operation of placing insulation material comprising fibers and binder on the fibers in a mold cavity. The molding process further includes the step of transferring heat to the insulation material to cause the binder to cure.