Patents by Inventor Wan-Heng Wang

Wan-Heng Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF GLYCOGEN SYNTHASE KINASE-3 (GSK-3) FOR TREATING GLAUCOMA
    Publication number: 20090312390
    Abstract: The use of inhibitors of GSK-3 useful for treating glaucoma is disclosed.
    Type: Application
    Filed: August 21, 2009
    Publication date: December 17, 2009
    Applicant: ALCON, INC.
    Inventors: Mark R. Hellberg, Abbot F. Clark, Iok-Hou Pang, Peggy Elizabeth Hellberg, Loretta Graves McNatt, Wan-Heng Wang
  • Inhibitors of glycogen synthase kinase-3 (GSK-3) for treating glaucoma
    Patent number: 7598288
    Abstract: The use of inhibitors of GSK-3 useful for treating glaucoma is disclosed.
    Type: Grant
    Filed: September 23, 2002
    Date of Patent: October 6, 2009
    Assignee: Alcon, Inc.
    Inventors: Mark R. Hellberg, Abbot F. Clark, Iok-Hou Pang, Peggy Elizabeth Hellberg, Loretta Graves McNatt, Wan-Heng Wang
  • Diagnostics and Therapeutics For Glaucoma
    Publication number: 20090226425
    Abstract: Methods and compositions for diagnosing and treating glaucoma are disclosed.
    Type: Application
    Filed: April 9, 2009
    Publication date: September 10, 2009
    Applicants: ALCON, INC., UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Abbot F. Clark, John Fingert, Loretta McNatt, Edwin M. Stone, Wan-Heng Wang
  • Injection aid for anterior juxtascleral depot
    Publication number: 20090192458
    Abstract: The present invention is an ophthalmic injection aid having a positioning member and a needle assembly. The injection aid facilitates the creation of an anterior juxtascleral depot of an ophthalmic drug.
    Type: Application
    Filed: January 22, 2009
    Publication date: July 30, 2009
    Inventors: Wan-Heng Wang, Liezhi Liang
  • Use of Serum Amyloid A Gene in Diagnosis and Treatment of Glaucoma and Identification of Anti-Glaucoma Agents
    Publication number: 20090036371
    Abstract: The present invention provides compositions and methods for treating glaucoma, methods for diagnosing glaucoma, and methods for identifying agents which may be useful in the treatment of glaucoma. More specifically, the present invention describes the use of agents that modulate the expression of serum amyloid A.
    Type: Application
    Filed: February 27, 2008
    Publication date: February 5, 2009
    Applicant: ALCON, INC.
    Inventors: Abbot F. CLARK, Wan-Heng WANG, Loretta MCNATT
  • Use of serum amyloid a gene in diagnosis and treatment of glaucoma and identification of anti-glaucoma agents
    Patent number: 7357931
    Abstract: The present invention provides compositions and methods for treating glaucoma, methods for diagnosing glaucoma, and methods for identifying agents which may be useful in the treatment of glaucoma. More specifically, the present invention describes the use of agents that modulate the expression of serum amyloid A.
    Type: Grant
    Filed: December 1, 2004
    Date of Patent: April 15, 2008
    Assignee: Alcon, Inc.
    Inventors: Abbot F. Clark, Wan-Heng Wang, Loretta McNatt
  • SUPEROXIDE DISMUTASE-2 EXPRESSION AND MODULATION FOR GLAUCOMA DIAGNOSIS AND THERAPY
    Publication number: 20080085878
    Abstract: The present invention concerns a method for diagnosing or monitoring elevated intraocular pressure or glaucoma in a patient comprising providing a biological sample from the patient and measuring the expression level of a superoxide dismutase-2 (SOD-2) gene in the biological sample. The present invention also concerns methods for treating glaucoma or elevated intraocular pressure in a patient comprising administering to a patient an effective amount of an agent that modulates SOD-2 expression or SOD-2 activity.
    Type: Application
    Filed: February 28, 2007
    Publication date: April 10, 2008
    Applicant: ALCON MANUFACTURING, LTD.
    Inventors: Wan-Heng WANG, Loretta McNatt, Abbot CLARK, Peter KLIMKO
  • Use of Serum Amyloid A Gene in Diagnosis and Treatment of Glaucoma and Identification of Anti-Glaucoma Agents
    Publication number: 20070208043
    Abstract: The present invention provides compositions and methods for treating glaucoma, methods for diagnosing glaucoma, and methods for identifying agents which may be useful in the treatment of glaucoma. More specifically, the present invention describes the use of agents that modulate the expression of serum amyloid A.
    Type: Application
    Filed: December 22, 2006
    Publication date: September 6, 2007
    Applicant: ALCON, INC.
    Inventors: Abbot Clark, Wan-Heng Wang, Loretta McNatt
  • RNAi-mediated inhibition of Frizzled Related Protein-1 for treatment of glaucoma
    Publication number: 20060223773
    Abstract: RNA interference is provided for inhibition of Frizzled Related Protein-1 mRNA expression, in particular, for treating patients having glaucoma or at risk of developing glaucoma.
    Type: Application
    Filed: March 10, 2006
    Publication date: October 5, 2006
    Applicant: Alcon, Inc.
    Inventors: Abbot Clark, Wan-Heng Wang, Loretta McNatt, Jon Chatterton
  • Diagnostics and therapeutics for glaucoma
    Publication number: 20060216732
    Abstract: Methods and compositions for diagnosing and treating glaucoma are disclosed.
    Type: Application
    Filed: January 6, 2006
    Publication date: September 28, 2006
    Inventors: Abbot Clark, John Fingert, Loretta McNatt, Edwin Stone, Wan-Heng Wang
  • RNAi inhibition of serum amyloid a for treatment of glaucoma
    Publication number: 20060172961
    Abstract: RNA interference is provided for inhibition of serum amyloid A mRNA expression in glaucomas involving SAA expression.
    Type: Application
    Filed: December 19, 2005
    Publication date: August 3, 2006
    Applicant: Alcon, Inc.
    Inventors: Abbot Clark, Wan-Heng Wang, Loretta McNatt
  • Method of reducing intraocular pressure and treating glaucoma
    Publication number: 20060154981
    Abstract: The use of 5,6,7-trihydroxyheptanoic acid and analogs for the treatment of ocular hypertension and glaucoma is disclosed.
    Type: Application
    Filed: January 12, 2006
    Publication date: July 13, 2006
    Inventors: Peter Klimko, Mark Hellberg, Wan-Heng Wang, Abbot Clark, Loretta McNatt
  • Agents which regulate, inhibit, or modulate the activity and/or expression of formyl peptide receptors as a unique means to both lower intraocular pressure and treat glaucomatous retinopathies/optic neuropathies
    Publication number: 20060134171
    Abstract: The present invention provides a method for lowering intraocular pressure and providing neuroprotection to a patient in need thereof by administering a therapeutically effective amount of at least one non-nucleotide or non-protein agent that inhibits expression and/or signaling of FPR.
    Type: Application
    Filed: December 1, 2005
    Publication date: June 22, 2006
    Inventors: Loretta McNatt, Wan-Heng Wang, Abbot Clark
  • Diagnostics and therapeutics for glaucoma
    Patent number: 7033755
    Abstract: Methods and compositions for diagnosing and treating glaucoma are disclosed.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: April 25, 2006
    Assignees: Alcon, Inc., University of Iowa Research Foundation
    Inventors: Abbot F. Clark, John Fingert, Loretta McNatt, Edwin M. Stone, Wan-Heng Wang
  • Diagnosis and treatment of glaucoma and methods for discovering new glaucoma therapeutic agents based on the wnt/ca2+ signaling pathway
    Publication number: 20050170430
    Abstract: The present invention provides methods for diagnosing and treating glaucoma and identifying agents potentially useful for treating glaucoma. The invention further provides compositions useful for treating glaucoma.
    Type: Application
    Filed: April 30, 2003
    Publication date: August 4, 2005
    Inventors: Abbot Clark, Wan-Heng Wang, Loretta McNatt
  • Diagnosis and treatment of glaucoma and methods for discovering new glaucoma therapeutic agents based on the wnt/planar cell polarity (pcp) signaling pathway
    Publication number: 20050164907
    Abstract: The present invention provides methods for diagnosing and treating glaucoma and identifying agents potentially useful for treating glaucoma. The invention further provides compositions useful for treating glaucoma.
    Type: Application
    Filed: April 30, 2003
    Publication date: July 28, 2005
    Inventors: Abbot Clark, Wan-Heng Wang, Loretta McNatt
  • Use of serum amyloid a gene in diagnosis and treatment of glaucoma and identification of anti-glaucoma agents
    Publication number: 20050153927
    Abstract: The present invention provides compositions and methods for treating glaucoma, methods for diagnosing glaucoma, and methods for identifying agents which may be useful in the treatment of glaucoma. More specifically, the present invention describes the use of agents that modulate the expression of serum amyloid A.
    Type: Application
    Filed: December 1, 2004
    Publication date: July 14, 2005
    Inventors: Abbot Clark, Wan-Heng Wang, Loretta McNatt
  • Inhibitors of glycogen synthase kinase-3 (gsk-3) for treating glaucoma
    Publication number: 20040186159
    Abstract: The use of inhibitors of GSK-3 useful for treating glaucoma is disclosed.
    Type: Application
    Filed: March 2, 2004
    Publication date: September 23, 2004
    Inventors: Mark R. Hellberg, Abbott F. Clark, Iok-Hou Pang, Peggy Elizabeth Hellberg, Loretta Graves McNatt, Wan-Heng Wang
  • Compositions and methods for directly and rapidly analyzing the biochemical components of microorganisms
    Patent number: 6723514
    Abstract: This invention concerns novel methods and compositions useful for directly and rapidly analyzing the biochemical components of microorganisms. The compositions and methods of the present invention obviate the need for extracting and purifying the biochemicals prior to analysis.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: April 20, 2004
    Assignee: Biochaiv Institute, Inc.
    Inventors: Sean Xiaoliang Han, Wan-Heng Wang
  • Diagnostics and therapeutics for glaucoma
    Publication number: 20020049177
    Abstract: Methods and compositions for diagnosing and treating glaucoma are disclosed.
    Type: Application
    Filed: February 28, 2001
    Publication date: April 25, 2002
    Inventors: Abbot F. Clark, John Fingert, Loretta McNatt, Edwin Stone, Wan-Heng Wang