Abstract: The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.

Abstract: The present disclosure relates to non-naturally occurring polypeptides useful for preparing Ezetimibe, polynucleotides encoding the polypeptides, and methods of using the polypeptides.

Abstract: The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.

Abstract: A structure with detachable battery for an electronic device includes an electronic device casing, a guiding structure, and a sliding tongue. The electronic device casing has a chamber for receiving a battery. The guiding structure is disposed on an outer sidewall of a battery. The guiding structure includes a guiding groove. The guiding groove and the chamber are open toward each other. An engaging groove is laterally disposed in the guiding groove. The engaging groove is open in a transverse direction of the chamber. A releasing-guiding slope opposite the engaging groove is disposed in the guiding groove to extend from the opening of the guiding groove and tilt toward the engaging groove. The sliding tongue is disposed slidably on an inner sidewall of the chamber such that battery becomes fixed inside the chamber or slidably abuts against the releasing-guiding slope, thereby ejecting the battery out of the chamber.

Abstract: The present disclosure relates to biocatalysts and its uses for the efficient preparation of eslicarbazepine, eslicarbazepine acetate, and analogs thereof.

Abstract: The present disclosure provides engineered pNB esterase polypeptides useful for the synthesis of the carbapenem antibiotic, imipenem. The disclosure also provides polynucleotides encoding the engineered pNB esterases, host cells capable of expressing the engineered pNB esterases, and methods of using the engineered pNB esterases in the production of imipenem.

Abstract: The present disclosure relates to non-naturally occurring polypeptides useful for preparing Ezetimibe, polynucleotides encoding the polypeptides, and methods of using the polypeptides.

Abstract: The present disclosure relates to biocatalysts and its uses for the efficient preparation of eslicarbazepine, eslicarbazepine acetate, and analogs thereof.

Abstract: The present disclosure provides acyltransferases useful for synthesizing therapeutically important statin compound.

Abstract: The present disclosure provides engineered pNB esterase polypeptides useful for the synthesis of the carbapenem antibiotic, imipenem. The disclosure also provides polynucleotides encoding the engineered pNB esterases, host cells capable of expressing the engineered pNB esterases, and methods of using the engineered pNB esterases in the production of imipenem.

Abstract: An electronic device includes an antenna, a wireless transmitter, a proximity sensor and a controller. The antenna includes a first radiating element and a second radiating element which has a different length than the first radiating element. The wireless transmitter is to send a radio signal to the antenna and the controller is to disable the first radiating element in response to the proximity sensor detecting a body part.

Abstract: The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.

Abstract: The present disclosure provides acyltransferases useful for synthesizing therapeutically important statin compound.

Abstract: The present disclosure provides engineered pNB esterase polypeptides useful for the synthesis of the carbapenem antibiotic, imipenem. The disclosure also provides polynucleotides encoding the engineered pNB esterases, host cells capable of expressing the engineered pNB esterases, and methods of using the engineered pNB esterases in the production of imipenem.

Abstract: The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.

Abstract: Example implementations relate to enabling a radiating element based on an orientation signal. For example, a method may include receiving at a controller of a computing device an orientation signal from an orientation sensor. The orientation signal corresponds to a first orientation of an antenna element of the computing device. The method may also include enabling via the controller a first radiating element of the antenna element based on the orientation signal. The method may further include disabling via the controller a second radiating element of the antenna element based on the orientation signal.

Abstract: The present disclosure relates to non-naturally occurring polypeptides useful for preparing Ezetimibe, polynucleotides encoding the polypeptides, and methods of using the polypeptides.

Abstract: The present disclosure relates to biocatalysts and its uses for the efficient preparation of eslicarbazepine, eslicarbazepine acetate, and analogs thereof.

Abstract: A method of etching features into a silicon layer with a steady-state gas flow is provided. An etch gas comprising an oxygen containing gas and a fluorine containing gas is provided. A plasma is provided from the etch gas. Then, the flow of the etch gas is stopped.

Abstract: A multiple-fluid system generates waveforms at its fluid interface, e.g. in a manner to prevent complete dewetting of a surface by the electrically non-conductive fluid and/or wetting of the surface by the electrically conductive fluid. In an example, a feedback controller senses capacitance across the non-conductive fluid, e.g. between one or more electrodes on the substrate and the conductive fluid. This first example controls voltages applied to the electrodes, based on the capacitive sensing, to create a static waveform, such as a standing wave, at the fluid interface. Another example manipulates the voltages applied to the electrodes to generate a propagating wave at the fluid interface.