Abstract: An embodiment multi-way coolant valve includes an outer housing including first to third outer inlets, first to third outer outlets, and a pump mount portion coupled to one of the outer outlets, an inner housing rotatably provided within the outer housing and including penetration holes corresponding to the outer inlets and outlets, a coolant line defined by a selective connection of the penetration holes such that the outer inlets and outlets are selectively connected, pads interposed between an interior circumference of the outer housing and an exterior circumference of the inner housing at locations of the outer inlets and outlets, respectively, and a driving device connected to a rotation center of the inner housing to selectively rotate the inner housing within the outer housing, wherein the inner housing is configured to rotate by a preset interval according to a selected vehicle mode.

Abstract: The present invention relates to a recombinant adenovirus expressing an ?A-crystallin gene, and gene therapy for retinal vascular disease using the recombinant adenovirus. Gene therapy using the recombinant adenovirus comprising an ?A-crystallin gene of the present invention increases the expression level of the ?A-crystallin gene in the damaged retinal pericytes to suppress pericyte loss and death, retinal vascular leakage, and leukocyte adhesion surrounding retinal vessels, thereby protecting the pericytes. Therefore, it can be used for the prevention and treatment of various retinal vascular diseases including diabetic retinopathy.

Abstract: An improved video signal processing circuit employs a control signal generating device, first and second delay circuits, a signal selection circuit, an addition circuit, a subtraction circuit, and an addition/subtraction circuit. The signal selection circuit is responsive to switch control signals from the control signal generating device for selecting a first signal path when providing signal contour compensation or a second signal path when functioning as a sensitivity enhancement device. At the final output terminal of the present circuit is produced a contour-compensated luminance signal under medium or high illumination selection control and an enlarged luminance signal without noise under low illumination selection control. Mode change is a function of and dependent on the amount of incident light to be automatically achieved by the control signal generating device.