Patents by Inventor Wanchao Ma

Wanchao Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ZINC ASSOCIATED TREATMENT FOR AND DIAGNOSIS OF CACHEXIA
    Publication number: 20210071183
    Abstract: The present invention provides methods of diagnosing and treating cancer-induced cachexia using a zinc transporter as a biomarker and a therapeutic target. The method for diagnosing cachexia includes monitoring Zip 14-mediated zinc accumulation in the patient's muscle. The method for treating cachexia includes administering a pharmaceutical composition to reduce the Zip 14-mediated zinc accumulation in the patient's muscle.
    Type: Application
    Filed: January 24, 2019
    Publication date: March 11, 2021
    Inventors: Swarnali ACHARYYA, Anup K. BISWAS, Wanchao MA, Courtney COKER, Gang WANG
  • CLEARANCE OF BIOACTIVE LIPIDS FROM MEMBRANE STRUCTURES BY CYCLODEXTRINS
    Publication number: 20160151410
    Abstract: The present invention provides a method of treating a subject suffering from wet acute macular degeneration which comprises administering to the subject an amount of a modified alpha cyclodextrin effective to treat the subject, wherein the modified alpha cyclodextrin binds to bioactive lipids which accumulate in the subject's eye and are characterized by the presence of a single chain of fatty acids.
    Type: Application
    Filed: June 30, 2014
    Publication date: June 2, 2016
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Wanchao MA, Gaetano R. BARILE, David Choohyun PAIK
  • RAGE AS A C1Q RECEPTOR, METHODS AND APPLICATIONS
    Publication number: 20160139120
    Abstract: A method of identifying a compound capable of reducing or increasing the amount of the receptor for RAGE-C1q Binding comprising a) providing an amount of the compound to be tested; b) contacting the amount of the compound with C1q and RAGE; c) measuring the amount of RAGE-C1q binding in step b); d) comparing the amount of RAGE-C1q binding measured in step c) with the amount of RAGE-C1q binding measured under corresponding conditions in the absence of the compound; and e) identifying the compound as capable of reducing or increasing the amount of RAGE-C1q binding. The present invention also provides a method of treating a subject suffering from a RAGE-related disorder comprising administering to the subject a therapeutically effective amount of a compound that is a modulator of the amount of RAGE-C1q binding so as to thereby treat the subject.
    Type: Application
    Filed: February 12, 2014
    Publication date: May 19, 2016
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Gaetano R. BARILE, Ann Marie SCHMIDT, Wanchao MA
  • Use of heme-peptides to prevent or retard disease associated with oxidative stress
    Patent number: 6013623
    Abstract: This invention provides a method for treating a condition associated with oxidative stress in a subject which comprises administering to the subject an amount of a heme-peptide effective to treat the condition associated with oxidative stress in the subject. The subject may be a mammal. The mammal may be a human being. The condition associated with oxidative stress may be an inflammatory condition, an allergic condition or an auto-immune condition.
    Type: Grant
    Filed: February 27, 1997
    Date of Patent: January 11, 2000
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Abraham Spector, Wanchao Ma, Ren-Rong Wang