Patents by Inventor Wang Bryan

Wang Bryan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EGFR binding peptides and uses thereof
    Patent number: 8536113
    Abstract: Short oligopeptides are provided which are capable of binding to the epidermal growth factor receptor on the surface of human tumor cells. Methods for using the peptides as targeting moieties in more complex compositions, such as conjugates of cytoxins, and/or structures, such as liposomal structures, for the purposes of drug delivery are also provided.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: September 17, 2013
    Assignee: Janssen Biotech, Inc.
    Inventors: Mohit Trikha, Wang Bryan, Frank Shi, John Kehoe
  • Dimeric high affinity EGFR constructs and uses thereof
    Patent number: 8278415
    Abstract: Polypeptides comprising EGFR extracellular domains I-III capable of forming dimeric EGF-binding proteins are provided. The dimeric construct of the invention is useful in applications where high affinity EGF binding is desired and can be used to select agents capable of binding to native EGFR in the presence of EGF.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: October 2, 2012
    Assignee: Centocor, Inc.
    Inventors: Wang Bryan, Frank Shi, Juliane Mills
  • EGFR BINDING PEPTIDES AND USES THEREOF
    Publication number: 20100151003
    Abstract: Short oligopeptides are provided which are capable of binding to the epidermal growth factor receptor on the surface of human tumor cells. Methods for using the peptides as targeting moieties in more complex compositions, such as conjugates of cytoxins, and/or structures, such as liposomal structures, for the purposes of drug delivery are also provided.
    Type: Application
    Filed: December 20, 2007
    Publication date: June 17, 2010
    Inventors: Mohit Trikha, Wang Bryan, Frank Shi, John Kehoe