Abstract: Compositions, including, for example, soluble Ryk polypeptides and Wnt polypeptides, that induce cell growth and/or differentiation, including, for example, neurite outgrowth and hematopoietic cell proliferation and differentiation, are provided. Methods of using such compositions also are provided, including, for example, methods of using such compositions to induce neurite outgrowth (e.g., in a subject having a neuronal disorder). In addition, methods to identify agents that alter Ryk mediated signal transduction in a cell are provided.

Abstract: Devices utilized for communication between a PC and a peripheral device, synchronization between the same, and supply of power to the peripheral device from the PC, are disclosed together with methods for their use. In one exemplary embodiment, a sync-charger cable accomplishes the above objectives using only the cable and its components, without the use of specialized and bulky hardware. For example, the sync-charger cable may consist of a data conversion unit operatively connected between a USB connector and a handheld device interface. The sync-charger cable operates both to exchange data and to deliver power, without utilizing an A/C adapter or a docking cradle.