Abstract: A coordinator module for improving communications within a cloud computing system is disclosed. The coordinator module initiates transaction requests by generating a coordination context, where the coordination context includes a transaction context, a coordination type, and an initiator supplemental address. The coordinator module includes a supplemental address handler for creating the initiator supplemental address that unique identifies the coordinator module and the associated pod. The coordinator module receives transaction responses, where the transaction response includes a coordination context. The coordinator module includes a transaction context checker to verify that the transaction response was not received in error, by comparing the received transaction context with a saved transaction context. The coordinator module includes a registration bridge that identifies an alternate coordinator module and alternate pod to process the transaction response if the transaction contexts do not match.

Abstract: A crosslinker composition is prepared from a reaction mixture including: (a) a prepolymer including a reaction product of a prepolymer mixture including: (i) a polyfunctional isocyanate; and (ii) a first compound comprising two or more active hydrogen groups, where the polyfunctional isocyanate and/or the first compound comprising two or more active hydrogen groups includes a greater than two functional isocyanate and/or active hydrogen groups, respectively; and (b) a polyfunctional hydrazide. The crosslinker composition is not self-crosslinkable. The crosslinker composition has an acid value of at least 15 based on total resin solids of the crosslinker composition.

Abstract: Intelligent process management is provided. A start time is determined for an additional process to be run on a worker node within a duration of a sleep state of a task of a process already running on the worker node by adding a first defined buffer time to a determined start time of the sleep state of the task. A backfill time is determined for the additional process by subtracting a second defined buffer time from a determined end time of the sleep state of the task. A scheduling plan is generated for the additional process based on the start time and the backfill time corresponding to the additional process. The scheduling plan is executed to run the additional process on the worker node according to the start time and the backfill time corresponding to the additional process.

Abstract: Disclosed are antigen binding polypeptides and antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) having certain structural and/or functional features. Also disclosed are polynucleotides and vectors encoding such polypeptides and polypeptide complexes; host cells, pharmaceutical compositions and kits containing such polypeptides and polypeptide complexes; and methods of using such polypeptides and polypeptide complexes.

Abstract: Provided herein are opioid receptor modulators and pharmaceutical compositions comprising said compounds.

Abstract: A system and method for simulating a transportation network is disclosed herein. A simulation may be configured at a configuration application, which enables designers and hyperloop operators to enter real-world constraints as alignment data. A plurality of travel scenarios may be run in order to generate simulated run results. An analytics engine may perform analysis on the simulated run results in order to inform designers and hyperloop operators seeking to improve the transportation network. A prediction modeler may be utilized to predict events occurring in the transportation network as simulated. Parallel processing may be utilized to increase the efficiency and speed of the simulation. The simulation may be performed before, during, and after the implementation of the transportation network.

Abstract: A method of retrieving data using metadata tags including identifying, by a processing circuit from a data structure, a digital representation of a device deployed within a space, tagging, by the processing circuit, a data point associated with the digital representation of the device with a semantic description having a tag schema, receiving, by the processing circuit, a query including a partial string referencing the tag schema, identifying, by the processing circuit, the semantic description from a plurality of semantic descriptions based on the partial string of the query and the tag schema, retrieving, by the processing circuit, one or more tagged data points by querying the data structure using the semantic description, and automatically performing an operation using the one or more tagged data points.

Abstract: In a described embodiment, a sensor-based communication apparatus (100) is disclosed. The communication apparatus (100) comprises a plurality of sensor nodes (112) associated with respective unique pulse signatures (200) and adapted to communicate with respective sensors (113) with each sensor (113) configured to generate a sensory signal (113a) in response to a respective stimulus (113b). Each sensor node (112) is triggered, upon receipt of the corresponding sensory signal (113a), to transmit the associated unique pulse signature (200) independently and asynchronously through a transmission medium (110) shared by the sensor nodes (112), and the unique pulse signatures (200) transmitted by the sensor nodes (112) being a representation (300) of a stimulus event associated with the stimuli detected by the corresponding sensors (113). A method and a communication medium are also disclosed.

Abstract: The present disclosure provides an acrylamide production system. The acrylamide production system includes a storage device, a reaction kettle, a filter device, an impurity removal device, and a collection device. The storage device is used for storing microbes required for a reaction. A discharge end of the storage device is connected to a feed end of the reaction kettle through a pipeline. A discharge end of the reaction kettle is connected to a feed end of the filter device through a pipeline. A filtrate discharge end of the filter device is connected to a feed end of the impurity removal device through a pipeline. A discharge end of the impurity removal device is connected to the collection device through a pipeline. According to the acrylamide production system of the present disclosure, the whole process for producing an acrylamide aqueous solution is simple, which facilitates producing a high-purity acrylamide solution.

Abstract: A semiconductor structure and a formation method thereof are disclosed. The formation method includes: providing a base, wherein a first mandrel layer and a first mask layer located on the first mandrel layer are formed on the base, and openings exposing the first mandrel layer are formed in the first mask layer; forming a second mandrel layer covering the first mask layer, wherein the second mandrel layer also fills the openings; forming first trenches running through the second mandrel layer, the first mask layer and the first mandrel layer, wherein the side walls of the first trenches expose the second mandrel layer in the openings; forming side wall layers on the side walls of the first trenches; and etching to remove the second mandrel layer and the first mandrel layer below the positions of the openings by taking the side wall layers as masks to form second trenches running through the first mandrel layer, wherein the second trenches and the first trenches are isolated by the side wall layers.

Abstract: A semiconductor structure and a forming method thereof are provided.

Abstract: A semiconductor structure and a formation method thereof are disclosed. The formation method includes: providing a base, wherein a first mandrel layer and a first mask layer located on the first mandrel layer are formed on the base, and openings exposing the first mandrel layer are formed in the first mask layer; forming a second mandrel layer covering the first mask layer, wherein the second mandrel layer also fills the openings; forming first trenches running through the second mandrel layer, the first mask layer and the first mandrel layer, wherein the side walls of the first trenches expose the second mandrel layer in the openings; forming side wall layers on the side walls of the first trenches; and etching to remove the second mandrel layer and the first mandrel layer below the positions of the openings by taking the side wall layers as masks to form second trenches running through the first mandrel layer, wherein the second trenches and the first trenches are isolated by the side wall layers.

Abstract: A semiconductor structure and a forming method thereof are provided.

Abstract: A brushless direct current electric motor assembly includes a housing having a first end and a second end and a stator disposed in the housing. The assembly further includes a rotor subassembly disposed in the stator, the rotor subassembly having a shaft having a first end proximate the first end of the housing and a second end proximate the second end of the housing. The assembly further includes a controller disposed in the housing, the controller configured to control rotation of the shaft. The first end of the shaft is configured to provide a rotational output.

Abstract: In a described embodiment, a sensor-based communication apparatus (100) is disclosed. The communication apparatus (100) comprises a plurality of sensor nodes (112) associated with respective unique pulse signatures (200) and adapted to communicate with respective sensors (113) with each sensor (113) configured to generate a sensory signal (113a) in response to a respective stimulus (113b). Each sensor node (112) is triggered, upon receipt of the corresponding sensory signal (113a), to transmit the associated unique pulse signature (200) independently and asynchronously through a transmission medium (110) shared by the sensor nodes (112), and the unique pulse signatures (200) transmitted by the sensor nodes (112) being a representation (300) of a stimulus event associated with the stimuli detected by the corresponding sensors (113). A method and a communication medium are also disclosed.

Abstract: Provided are combination therapies and related compositions and methods for treating cancers, including epithelial tumors, which include a combination of at least two agents such as an epidermal growth factor receptor (EGFR) inhibitor, a mitogen-activated protein kinase (MEK) 1/2 inhibitor; and a cyclin dependent kinase (CDK) 4/6 inhibitor.

Abstract: A brushless direct current electric motor assembly includes a housing having a first end and a second end and a stator disposed in the housing. The assembly further includes a rotor subassembly disposed in the stator, the rotor subassembly having a shaft having a first end proximate the first end of the housing and a second end proximate the second end of the housing. The assembly further includes a controller disposed in the housing, the controller configured to control rotation of the shaft. The first end of the shaft is configured to provide a rotational output.