Patents by Inventor Wange Lu

Wange Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF VprBP-RELATED CANCERS
    Publication number: 20160138026
    Abstract: This disclosure provides methods and compositions to inhibit or suppress tumor growth or to treat cancer by inhibiting VprBP kinase activity. Also provided are methods of determining the effectiveness of the methods and compositions to inhibit or suppress tumor growth or to treat cancer by inhibiting VprBP kinase activity, methods for detecting a cancer, and methods for screening potential agents that inhibit VprBP kinase activity.
    Type: Application
    Filed: January 11, 2016
    Publication date: May 19, 2016
    Inventors: Woojin An, Nouri Neamati, Kyunghwan Kim, Wange Lu
  • Compositions and methods for the treatment of VprBP-related cancers
    Patent number: 9234018
    Abstract: This disclosure provides methods and compositions to inhibit or suppress tumor growth or to treat cancer by inhibiting VprBP kinase activity. Also provided are methods of determining the effectiveness of the methods and compositions to inhibit or suppress tumor growth or to treat cancer by inhibiting VprBP kinase activity, methods for detecting a cancer, and methods for screening potential agents that inhibit VprBP kinase activity.
    Type: Grant
    Filed: October 14, 2014
    Date of Patent: January 12, 2016
    Assignee: University of Southern California
    Inventors: Woojin An, Nouri Neamati, Kyunghwan Kim, Wange Lu
  • Methods and compositions for inhibiting cell growth and proliferation
    Publication number: 20050158311
    Abstract: Compositions, including, for example, soluble Ryk polypeptides and/or agents that selectively bind Ryk, are provided. Methods of using such agents or compositions also are provided, including, for example, methods of using such compositions to inhibit proliferation of a cell exhibiting, or predisposed to exhibiting, unregulated growth. In addition, methods of ameliorating a cancer in a subject are provided.
    Type: Application
    Filed: October 22, 2004
    Publication date: July 21, 2005
    Applicant: California Institute of Technology
    Inventors: Wange Lu, David Baltimore
  • Compositions for inducing cell growth and differentiation and methods of using same
    Publication number: 20050153887
    Abstract: Compositions, including, for example, soluble Ryk polypeptides and Wnt polypeptides, that induce cell growth and/or differentiation, including, for example, neurite outgrowth and hematopoietic cell proliferation and differentiation, are provided. Methods of using such compositions also are provided, including, for example, methods of using such compositions to induce neurite outgrowth (e.g., in a subject having a neuronal disorder). In addition, methods to identify agents that alter Ryk mediated signal transduction in a cell are provided.
    Type: Application
    Filed: October 22, 2004
    Publication date: July 14, 2005
    Applicant: California Institute of Technology
    Inventors: Wange Lu, David Baltimore