Patents by Inventor Wangyu TONG

Wangyu TONG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Type I-B CRISPR-Cas system gene Cas3-based gene editing method
    Patent number: 11286506
    Abstract: A novel gene editing system developed based on the gene cas3 in the type I-B CRISPR-Cas system in the chromosome of Streptomyces virginiae IBL14 enables the gene editing of a type I CRISPR-Cas system on biological cell genomes for the first time. In the system, Cas3 can specifically cleave a DNA fragment of interest guided by crRNA or t-DNA. The new approach can be applied to rapid, simple and correct genome editing of prokaryotic and eukaryotic cells, which provides novel supplements and selections for the commercialized gene editing system developed based on Cas9 in type II.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: March 29, 2022
    Assignee: ANHUI UNIVERSITY
    Inventors: Wangyu Tong, Yanyan Tang, Tingting Xia
  • TYPE I-B CRISPR-CAS SYSTEM GENE CAS3-BASED GENE EDITING METHOD
    Publication number: 20190376089
    Abstract: A novel gene editing system developed based on the gene cas3 in the type I-B CRISPR-Cas system in the chromosome of Streptomyces virginiae IBL14 enables the gene editing of a type I CRISPR-Cas system on biological cell genomes for the first time. In the system, Cas3 can specifically cleave a DNA fragment of interest guided by crRNA or t-DNA. The new approach can be applied to rapid, simple and correct genome editing of prokaryotic and eukaryotic cells, which provides novel supplements and selections for the commercialized gene editing system developed based on Cas9 in type H.
    Type: Application
    Filed: July 24, 2018
    Publication date: December 12, 2019
    Applicant: ANHUI UNIVERSITY
    Inventors: Wangyu TONG, Yanyan TANG, Tingting XIA