Patents by Inventor Wanjun Lin

Wanjun Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING CANCER
    Publication number: 20190183856
    Abstract: One embodiment relates to a method of treating cancer by administering a compound of Formula I to a patient.
    Type: Application
    Filed: December 18, 2017
    Publication date: June 20, 2019
    Inventors: Wenzhe MA, Ying XIE, Xiaolin LIAO, Jiajun HUANG, Wanjun LIN, Ze LONG
  • Protein kinase C inhibitor for treating triple-negative breast cancer
    Publication number: 20170189391
    Abstract: Protein kinase C plays important roles in TNBC development and could be a specific target. The in vitro anti-proliferative activity of PKC inhibitor chelerythrine on a panel of breast cancer cell lines was evaluated. Chelerythrine selectively inhibited the growth of TNBC cell lines over non-TNBC cell lines as demonstrated by cell proliferation assay and colony formation assay. The selective anti-proliferative effect of chelerythrine was associated with the differential apoptosis induction ability on breast cancer cell lines and induction of cell cycle arrest in some TNBC cell lines. By analysis of the expression levels of different PKC subtypes, the inventors found multiple PKC isozymes may mediate the selective activity of chelerythrine on TNBC cells. Finally, combination of chelerythrine and chemotherapy reagent taxol showed synergistic/additive effect on TNBC cell lines.
    Type: Application
    Filed: December 31, 2015
    Publication date: July 6, 2017
    Inventors: Ying Xie, Wenzhe Ma, Wanjun Lin, Jiajun Huang, Zhongwen Yuan, Shengling Feng