Patents by Inventor Wanqi Yang

Wanqi Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Class of functional molecules targeting proteolysis pathways, preparation and application thereof
    Patent number: 12331059
    Abstract: The present invention belongs to the field of medical technology and relates to a class of functional small molecules targeting proteolysis pathways, a preparation and an application thereof. Specifically, the present invention relates to functional small molecules represented by formula (M) and pharmaceutically acceptable salts thereof, as well as the application of said compounds and pharmaceutical compositions thereof in the preparation of tumor-treating drugs. The functional small molecules are obtained by means of linking a compound containing a peroxide bridge linkage and a substrate of an E3 ubiquitin ligase complex. The related functional molecules can promiscuously target and bind to multiple proteins comprising functional proteins in the proteolysis pathway and have anti-tumor biological activity.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: June 17, 2025
    Assignee: Institute of Materia Medica, Chinese Academy of Medical Sciences
    Inventors: Chongjing Zhang, Fujia Wang, Zi Ye, Wanqi Yang, Ke Li
  • XRF QUANTITATIVE ANALYSIS METHOD OF HEAVY METAL ELEMENTS BASED ON LLE-SVR
    Publication number: 20240035991
    Abstract: Methods of XRF quantitative analysis of heavy metal elements based on LLE-SVR, such as may include: establishing a relationship between peak information and element content by using Local Linear Embedding Dimensionality For Reduction and Support Vector Regression Predictive Algorithms based on machine learning, to quantitatively analyze the content information of elements contained in substances.
    Type: Application
    Filed: March 17, 2023
    Publication date: February 1, 2024
    Inventors: Fusheng LI, Wanqi YANG, Yanchun ZHAO, Rongjiang TANG, Lu GAN
  • CLASS OF FUNCTIONAL MOLECULES TARGETING PROTEOLYSIS PATHWAYS, PREPARATION AND APPLICATION THEREOF
    Publication number: 20220380381
    Abstract: The present invention belongs to the field of medical technology and relates to a class of functional small molecules targeting proteolysis pathways, a preparation and an application thereof. Specifically, the present invention relates to functional small molecules represented by formula (M) and pharmaceutically acceptable salts thereof, as well as the application of said compounds and pharmaceutical compositions thereof in the preparation of tumor-treating drugs. The functional small molecules are obtained by means of linking a compound containing a peroxide bridge linkage and a substrate of an E3 ubiquitin ligase complex. The related functional molecules can promiscuously target and bind to multiple proteins comprising functional proteins in the proteolysis pathway and have anti-tumor biological activity.
    Type: Application
    Filed: September 9, 2020
    Publication date: December 1, 2022
    Applicant: Institute of Materia Medica, Chinese Academy of Medical Sciences
    Inventors: Chongjing Zhang, Fujia Wang, Zi Ye, Wanqi Yang, Ke Li