Abstract: Disclosed are a thiolated polysaccharide derivative hydrogel, a preparation method therefor, and use thereof. The thiolated polysaccharide derivative hydrogel is a thiolated hyaluronic acid polysaccharide derivative hydrogel or a thiolated chitin/chitosan derivative hydrogel. The thiolated hyaluronic acid polysaccharide derivative hydrogel is a polysaccharide hydrogel formed of one or two of thiolated hyaluronic acid derivatives and an aqueous solvent, and the thiolated chitin/chitosan derivative hydrogel is a polysaccharide hydrogel formed of one or two of thiolated chitin/chitosan derivatives and an aqueous solvent. The thiolated polysaccharide derivative hydrogel of the present invention is suitable for being used as a vitreous body substitute, and as the vitreous body substitute, can improve a shock absorption function, and can maintain the shape of an eyeball and press a retina in situ due to a good self-healing function and resilience.

Abstract: The invention relates to a medical material, especially to a hemostatic and wound-healing water-soluble chitosan-based fiber material. The water-soluble chitosan-based fiber material comprises carboxymethyl chitosan fiber, hydroxypropyl chitosan fiber, hydroxyethyl chitosan fiber, carboxymethyl hydroxyethyl chitosan fiber or mixtures thereof.