Patents by Inventor Wanxia He

Wanxia He has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INTRACELLULAR CX3CL1 DOMAIN PEPTIDES AND USES THEREOF
    Publication number: 20260055152
    Abstract: Described is a polypeptide including the intracellular domain of CX3CL1 (CX3CL1-ICD), including an amino acid sequence that is at least 90% identical to SEQ ID NO: 1 and pharmaceutical compositions including the above-described polypeptide and a pharmaceutically acceptable excipient. Also included are nucleic acids expressing the polypeptides and expression cassettes and vectors comprising the nucleic acids. The polypeptides can be used in methods of treating a subject exhibiting a symptom of a neurodegenerative disease and/or diagnosed with a neurodegenerative disease and methods of treating a subject exhibiting a symptom of diabetes and/or diagnosed with diabetes comprising administering to the subject the pharmaceutical composition described herein.
    Type: Application
    Filed: August 31, 2023
    Publication date: February 26, 2026
    Inventors: Riqiang YAN, Manoshi GAYEN, Wanxia HE
  • Methods of identifying anti-viral agents
    Publication number: 20050032038
    Abstract: The invention provides methods to identify specific inhibitors of HPV E7 binding to CDK2 complex and methods to identify specific inhibitors of E7-induced CDK2 kinase activity. Specific inhibitors identified by the methods, compositions comprising the specific inhibitors, and methods of treatment using the compounds are also provided.
    Type: Application
    Filed: September 8, 2003
    Publication date: February 10, 2005
    Inventors: Christopher Fisher, Wanxia He
  • Methods of identifying anti-viral agents
    Patent number: 6641994
    Abstract: The invention provides methods to identify specific inhibitors of HPV E7 binding to CDK2 complex and methods to identify specific inhibitors of E7-induced CDK2 kinase activity. Specific inhibitors identified by the methods, compositions comprising the specific inhibitors, and methods of treatment using the compounds are also provided.
    Type: Grant
    Filed: December 1, 2000
    Date of Patent: November 4, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Christopher Fisher, Wanxia He
  • Methods of identifying anti-viral agents
    Publication number: 20010029022
    Abstract: The invention provides methods to identify specific inhibitors of HPV E7 binding to CDK2 complex and methods to identify specific inhibitors of E7-induced CDK2 kinase activity. Specific inhibitors identified by the methods, compositions comprising the specific inhibitors, and methods of treatment using the compounds are also provided.
    Type: Application
    Filed: December 1, 2000
    Publication date: October 11, 2001
    Inventors: Christopher Fisher, Wanxia He
  • Methods of identifying anti-viral agents
    Patent number: 6200746
    Abstract: The invention provides methods to identify specific inhibitors of HPV E7 binding to CDK2 and methods to identify specific inhibitors of E7-induced CDK2 kinase activity. Specific inhibitors identified by the methods, compositions comprising the specific inhibitors, and methods of treatment using the compounds are also provided.
    Type: Grant
    Filed: August 25, 1999
    Date of Patent: March 13, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventors: Christopher Fisher, Wanxia He