Patents by Inventor Warren D. Blackburn, Jr.

Warren D. Blackburn, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase
    Patent number: 5008283
    Abstract: This invention relates to the use of tenidap, 5-chloro-2,3-dihydro-2-oxo-3-(2-thienylcarbonyl)-indole-1-carboxamide, and the pharmaceutically-acceptable base salts thereof to inhibit activation of collagenase in a mammal and to inhibit the activity of myeloperoxidase in a mammal. This invention also relates to the use of tenidap and its salts for treating collagenase mediated disorders and diseases such as bone resorption disorders, corneal ulceration, periodontal disease, inflammatory disease and wounds of the skin and burns in mammals. The methods of this invention comprise administering an effective amount of tenidap or salts thereof to a mammal.
    Type: Grant
    Filed: March 19, 1990
    Date of Patent: April 16, 1991
    Assignee: Pfizer Inc.
    Inventors: Warren D. Blackburn, Jr., Leland D. Loose