Abstract: A transmit variable-width interface can be programmed to convert an electronic digital data path that is either 1N, 2N, 4N, or 8N bits wide into a data path that is 2N bits wide, either by serializing bits (4N- or 8N-bit cases), re-clocking bits (2N-bit case), or grouping bits (1N-bit case). A receive variable-width interface can be programmed to convert a data path 2N bits wide into a data path that is 1N, 2N, 4N, or 8N bits wide. The widths of the two variable-width data paths are controlled independently. The variable-width interfaces are coupled between a multi-gigabit transceiver and core logic of a programmable logic device. The incoming and outgoing data paths of the variable-width interfaces have separate clocks signals that are synchronized such that small amounts of skew in these clock signals do not disrupt the operation of the variable-width interfaces.