Patents by Inventor Warren P. Williamson, IV

Warren P. Williamson, IV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11872565
    Abstract: A method for preparing one or more biopsy tissue samples for histological examination includes positioning a tissue sample in a tissue cassette, closing a peripheral portion of a frame including a cassette lid, and moving the lid and the tissue cassette from a first position to a second position. The tissue cassette is coupled to a frame by a frame-cassette connector and moving the lid and the tissue cassette from the first position to the second position includes breaking the frame-cassette connector. The tissue cassette has a recess including at least one side wall and a bottom wall and is formed of a first material that can be successfully sectioned in a microtome. In the second position, the bottom wall and at least a portion of the side wall extend downwardly beyond a bottom edge of the frame for sectioning in the microtome.
    Type: Grant
    Filed: October 20, 2022
    Date of Patent: January 16, 2024
    Assignee: BIOPATH AUTOMATION, LLC
    Inventor: Warren P. Williamson, IV
  • Publication number: 20240011875
    Abstract: A sectionable tissue sample support structure including a gel compound formed into a self supporting geometric shape for retention and orientation of at least one tissue sample during a histopathology process including processing, embedding and microtome slicing of the tissue sample. A method of orienting, processing, embedding and microtome slicing a tissue sample using a gel compound preformed into a self supporting geometric shape. A combination including the sectionable tissue sample support structure and a package containing the sectionable tissue sample support structure.
    Type: Application
    Filed: September 26, 2023
    Publication date: January 11, 2024
    Inventors: Warren P. Williamson, IV, Richard W. Dapson, Amit D. Shah
  • Publication number: 20230375444
    Abstract: A histologic tissue sample support device includes a tissue cassette a frame, and a lid. The tissue cassette has a recess including a body with at least one side wall and a bottom wall and is formed of material that can be successfully sectioned in a microtome and is resistant to degradation from solvents and chemicals used to fix, process and stain tissue. The tissue cassette is movably coupled to the frame. The lid and the tissue cassette are capable of moving from a first position to a second position with respect to the frame, and in the second position the bottom wall and at least a portion of the side wall extend beyond a bottom edge of the frame for sectioning in the microtome.
    Type: Application
    Filed: August 3, 2023
    Publication date: November 23, 2023
    Inventor: Warren P. Williamson, IV
  • Patent number: 11796429
    Abstract: A sectionable tissue sample support structure including a gel compound formed into a self supporting geometric shape for retention and orientation of at least one tissue sample during a histopathology process including processing, embedding and microtome slicing of the tissue sample. A method of orienting, processing, embedding and microtome slicing a tissue sample using a gel compound preformed into a self supporting geometric shape. A combination including the sectionable tissue sample support structure and a package containing the sectionable tissue sample support structure.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: October 24, 2023
    Assignees: BIOPATH AUTOMATION, LLC, SAKURA FINETEK U.S.A., INC.
    Inventors: Warren P. Williamson, IV, Richard W. Dapson, Amit D. Shah
  • Patent number: 11774330
    Abstract: A histologic tissue sample support device includes a tissue cassette a frame, and a lid. The tissue cassette has a recess including a body with at least one side wall and a bottom wall and is formed of material that can be successfully sectioned in a microtome and is resistant to degradation from solvents and chemicals used to fix, process and stain tissue. The tissue cassette is movably coupled to the frame. The lid is separably coupled to a peripheral portion of the frame. When the lid is separated from the peripheral portion, the lid and the tissue cassette are capable of moving from a first position to a second position with respect to the frame, and in the second position the bottom wall and at least a portion of the side wall extend beyond a bottom edge of the frame for sectioning in the microtome.
    Type: Grant
    Filed: December 7, 2021
    Date of Patent: October 3, 2023
    Assignee: BioPath Automation, LLC
    Inventor: Warren P. Williamson, IV
  • Publication number: 20230041034
    Abstract: A method for manufacturing a histologic tissue sample support device includes molding a tissue cassette, molding a frame, and coupling the tissue cassette to the frame by assembling a frame-cassette connector. The tissue cassette has a recess including at least one side wall and a bottom wall. The tissue cassette is formed of a first material that can be successfully sectioned in a microtome and is resistant to degradation from solvents and chemicals used to fix, process and stain tissue. The frame includes a bottom edge and is formed of a second material different from the first material and more rigid than the first material. The frame-cassette connector includes a first retaining structure formed integrally with the frame extending through a second retaining structure formed integrally with the cassette. The frame is capable of being decoupled from the cassette by separating the frame-cassette connector.
    Type: Application
    Filed: October 20, 2022
    Publication date: February 9, 2023
    Inventor: Warren P. Williamson, IV
  • Publication number: 20230041994
    Abstract: A method for preparing one or more biopsy tissue samples for histological examination includes positioning a tissue sample in a tissue cassette, closing a peripheral portion of a frame including a cassette lid, and moving the lid and the tissue cassette from a first position to a second position. The tissue cassette is coupled to a frame by a frame-cassette connector and moving the lid and the tissue cassette from the first position to the second position includes breaking the frame-cassette connector. The tissue cassette has a recess including at least one side wall and a bottom wall and is formed of a first material that can be successfully sectioned in a microtome. In the second position, the bottom wall and at least a portion of the side wall extend downwardly beyond a bottom edge of the frame for sectioning in the microtome.
    Type: Application
    Filed: October 20, 2022
    Publication date: February 9, 2023
    Inventor: Warren P. Williamson, IV
  • Publication number: 20230040801
    Abstract: A histologic tissue sample support device includes a tissue cassette, a frame, and a lid. The tissue cassette has a recess including at least one side wall and a bottom wall and is formed of material that can be successfully sectioned in a microtome and is resistant to degradation from solvents and chemicals used to fix, process and stain tissue. The lid is coupled to the frame and includes a platen configured to be received within the recess of the tissue cassette. The tissue cassette is movably coupled to the frame by a frame-cassette connector. The lid and the tissue cassette are capable of moving from a first position to a second position with respect to the frame, and in the second position the bottom wall and at least a portion of the side wall extend beyond a bottom edge of the frame for sectioning in a microtome.
    Type: Application
    Filed: October 20, 2022
    Publication date: February 9, 2023
    Inventor: Warren P. Williamson, IV
  • Publication number: 20230035804
    Abstract: A histologic tissue sample support device includes a tissue cassette, a frame, a lid, and a frame-cassette connector. The tissue cassette formed of a first material has a recess including a body with at least one side wall and a bottom wall and is formed of material that can be successfully sectioned in a microtome and is resistant to degradation from solvents and chemicals used to fix, process and stain tissue. The tissue cassette is movably coupled to the frame by a frame-cassette connector. The lid is coupled to the frame. The lid and the tissue cassette are capable of moving from a first position to a second position with respect to the frame, and in the second position the bottom wall and at least a portion of the side wall extend beyond a bottom edge of the frame for sectioning in a microtome.
    Type: Application
    Filed: October 17, 2022
    Publication date: February 2, 2023
    Inventor: Warren P. Williamson, IV
  • Patent number: 11498077
    Abstract: A histologic tissue sample support device includes a tissue cassette, a frame, and a lid. The tissue cassette has a recess including a body with at least one side wall and a bottom wall and is formed of material that can be successfully sectioned in a microtome and is resistant to degradation from solvents and chemicals used to fix, process and stain tissue. The tissue cassette is movably coupled to the frame by a frame-cassette connector. The lid is coupled to a peripheral portion of the frame by a lid-frame connector. The lid and the tissue cassette are capable of moving from a first position to a second position with respect to the frame, and in the second position the bottom wall and at least a portion of the side wall extend beyond a bottom edge of the frame for sectioning in a microtome.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: November 15, 2022
    Assignee: BioPath Automation, LLC
    Inventor: Warren P. Williamson, IV
  • Publication number: 20220090996
    Abstract: A histologic tissue sample support device includes a tissue cassette a frame, and a lid. The tissue cassette has a recess including a body with at least one side wall and a bottom wall and is formed of material that can be successfully sectioned in a microtome and is resistant to degradation from solvents and chemicals used to fix, process and stain tissue. The tissue cassette is movably coupled to the frame. The lid is separably coupled to a peripheral portion of the frame. When the lid is separated from the peripheral portion, the lid and the tissue cassette are capable of moving from a first position to a second position with respect to the frame, and in the second position the bottom wall and at least a portion of the side wall extend beyond a bottom edge of the frame for sectioning in the microtome.
    Type: Application
    Filed: December 7, 2021
    Publication date: March 24, 2022
    Inventor: Warren P. Williamson, IV
  • Patent number: 11226272
    Abstract: A histologic tissue sample support device includes a tissue cassette a frame, and a lid. The tissue cassette has a recess including a body with at least one side wall and a bottom wall and is formed of material that can be successfully sectioned in a microtome and is resistant to degradation from solvents and chemicals used to fix, process and stain tissue. The tissue cassette is movably coupled to the frame. The lid is separably coupled to a peripheral portion of the frame. When the lid is separated from the peripheral portion, the lid and the tissue cassette are capable of moving from a first position to a second position with respect to the frame, and in the second position the bottom wall and at least a portion of the side wall extend beyond a bottom edge of the frame for sectioning in the microtome.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: January 18, 2022
    Assignee: BioPath Automation, LLC
    Inventor: Warren P. Williamson, IV
  • Publication number: 20210138476
    Abstract: A histologic tissue sample support device includes a tissue cassette, a frame, and a lid. The tissue cassette has a recess including a body with at least one side wall and a bottom wall and is formed of material that can be successfully sectioned in a microtome and is resistant to degradation from solvents and chemicals used to fix, process and stain tissue. The tissue cassette is movably coupled to the frame by a frame-cassette connector. The lid is coupled to a peripheral portion of the frame by a lid-frame connector. The lid and the tissue cassette are capable of moving from a first position to a second position with respect to the frame, and in the second position the bottom wall and at least a portion of the side wall extend beyond a bottom edge of the frame for sectioning in a microtome.
    Type: Application
    Filed: November 12, 2019
    Publication date: May 13, 2021
    Inventor: Warren P. Williamson, IV
  • Publication number: 20200408651
    Abstract: A sectionable tissue sample support structure including a gel compound formed into a self supporting geometric shape for retention and orientation of at least one tissue sample during a histopathology process including processing, embedding and microtome slicing of the tissue sample. A method of orienting, processing, embedding and microtome slicing a tissue sample using a gel compound preformed into a self supporting geometric shape. A combination including the sectionable tissue sample support structure and a package containing the sectionable tissue sample support structure.
    Type: Application
    Filed: September 9, 2020
    Publication date: December 31, 2020
    Inventors: Warren P. Williamson, IV, Richard W. Dapson, Amit D. Shah
  • Patent number: 10794804
    Abstract: A sectionable tissue sample support structure including a gel compound formed into a self supporting geometric shape for retention and orientation of at least one tissue sample during a histopathology process including processing, embedding and microtome slicing of the tissue sample. A method of orienting, processing, embedding and microtome slicing a tissue sample using a gel compound preformed into a self supporting geometric shape. A combination including the sectionable tissue sample support structure and a package containing the sectionable tissue sample support structure.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: October 6, 2020
    Assignees: BioPath Automation, LLC, Sakura Finetek U.S.A., Inc.
    Inventors: Warren P. Williamson, IV, Richard W. Dapson, Amit D. Shah
  • Publication number: 20190254672
    Abstract: A clamp having at least first and second elongate clamping portions adapted to be placed on opposite sides of the hollow anatomical structure. The first and second elongate clamping portions respectively include ends coupled together with respective resilient urging members configured to urge at least one of the first and second elongate clamping portions toward the other of the first and second elongate clamping portions from an open position into a clamping position to occlude the hollow anatomical structure. The clamp includes tissue ingrowth structure on the clamping portions.
    Type: Application
    Filed: April 30, 2019
    Publication date: August 22, 2019
    Inventors: Warren P. Williamson, IV, Delos M. Cosgrove, III
  • Patent number: 10314585
    Abstract: A clamp having at least first and second elongate clamping portions adapted to be placed on opposite sides of the hollow anatomical structure. The first and second elongate clamping portions respectively include ends coupled together with respective resilient urging members configured to urge at least one of the first and second elongate clamping portions toward the other of the first and second elongate clamping portions from an open position into a clamping position to occlude the hollow anatomical structure. The clamp includes tissue ingrowth structure on the clamping portions.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: June 11, 2019
    Assignees: IDx Medical, Ltd., The Cleveland Clinic Foundation
    Inventors: Warren P. Williamson, IV, Delos M. Cosgrove, III
  • Patent number: 10285712
    Abstract: A method of occluding an appendage of the heart with a clamp including at least first and second elongate clamping portions, the first and second elongate clamping portions including tissue engaging surfaces that promote tissue ingrowth. The method includes implanting the clamp by positioning the first and second elongate clamping portions on opposite sides of the appendage. At least one of the first or second elongate clamping portions is biased toward the other of the first and second elongate clamping portions to place the clamp into a clamping position on the appendage. Tissue ingrowth into the tissue engaging surfaces retains the clamp in place on the appendage.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: May 14, 2019
    Assignees: Idx Medical, Ltd., The Cleveland Clinic Foundation
    Inventors: Delos M. Cosgrove, III, Warren P. Williamson, IV, Craig B. Berky
  • Patent number: 10166024
    Abstract: A clamp having at least first and second elongate clamping portions adapted to be placed on opposite sides of the hollow anatomical structure. The first and second elongate clamping portions respectively include ends coupled together with respective resilient urging members configured to urge at least one of the first and second elongate clamping portions toward the other of the first and second elongate clamping portions from an open position into a clamping position to occlude the hollow anatomical structure. The clamp includes tissue ingrowth structure on the clamping portions.
    Type: Grant
    Filed: July 29, 2011
    Date of Patent: January 1, 2019
    Assignees: IDx Medical, Ltd., Atricure Inc., The Cleveland Clinic Foundation
    Inventors: Warren P. Williamson, IV, Jason I. Glithero, Michael W. Goldenbogen, Chadd R. Tyler, Todd A. Hall, Delos M. Cosgrove
  • Publication number: 20180156701
    Abstract: A histologic tissue sample support device includes a tissue cassette a frame, and a lid. The tissue cassette has a recess including a body with at least one side wall and a bottom wall and is formed of material that can be successfully sectioned in a microtome and is resistant to degradation from solvents and chemicals used to fix, process and stain tissue. The tissue cassette is movably coupled to the frame. The lid is separably coupled to a peripheral portion of the frame. When the lid is separated from the peripheral portion, the lid and the tissue cassette are capable of moving from a first position to a second position with respect to the frame, and in the second position the bottom wall and at least a portion of the side wall extend beyond a bottom edge of the frame for sectioning in the microtome.
    Type: Application
    Filed: February 2, 2018
    Publication date: June 7, 2018
    Inventor: Warren P. Williamson, IV