Patents by Inventor Warren R. Mikluka

Warren R. Mikluka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High affinity human antibodies to human IL-18 receptor
    Patent number: 8105805
    Abstract: An isolated antibody or antibody fragment that binds human interleukin-18 receptor alpha (hIL-18R?), comprising a light chain variable region (LCVR) selected from the group consisting of SEQ ID NO: 5, 9, 13, 17, 21, 25, 29, 33, 37, 41, 45, 49, 53, 61, 65, 69, 73, 77, and 81 and/or a heavy chain variable region (HCVR) selected from the group consisting of SEQ ID NO: 3, 7, 11, 15, 19, 23, 27, 31, 35, 39, 43, 47, 51, 55, 59, 63, 67, 71, 75, and 79, or a fragment or sequence modified by an amino acid substitution, deletion or addition thereof.
    Type: Grant
    Filed: July 18, 2011
    Date of Patent: January 31, 2012
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Tammy H. Huang, Sean Stevens, Joel H. Martin, Jeanette L. Fairhurst, Kevin J. Pobursky, Margaret Karow, Joan A. Windsor, Warren R. Mikluka
  • High Affinity Human Antibodies to Human IL-18 Receptor
    Publication number: 20110269187
    Abstract: An isolated antibody or antibody fragment that binds human interleukin-18 receptor alpha (hIL-18R?), comprising a light chain variable region (LCVR) selected from the group consisting of SEQ ID NO: 5, 9, 13, 17, 21, 25, 29, 33, 37, 41, 45, 49, 53, 61, 65, 69, 73, 77, and 81 and/or a heavy chain variable region (HCVR) selected from the group consisting of SEQ ID NO: 3, 7, 11, 15, 19, 23, 27, 31, 35, 39, 43, 47, 51, 55, 59, 63, 67, 71, 75, and 79, or a fragment or sequence modified by an amino acid substitution, deletion or addition thereof.
    Type: Application
    Filed: July 18, 2011
    Publication date: November 3, 2011
    Applicant: REGENERON PHARMACEUTICALS, INC.
    Inventors: TAMMY H. HUANG, SEAN STEVENS, JOEL H. MARTIN, JEANETTE L. FAIRHURST, KEVIN J. POBURSKY, MARGARET KAROW, JOAN A. WINDSOR, WARREN R. MIKLUKA