Abstract: The compound of formula (1a) wherein p is 1 or 2, R1-R4 are hydrogen atom or the like, and a-d are 1 or 2, or a pharmaceutically acceptable salt thereof, which has an antitumor effect by inhibiting the binding between a MLL fusion protein that is infused with AF4, AF9, or the like, which is a representative fusion partner gene causing MLL leukemia, and menin.

Abstract: A golf club head having a volume of from 400 cc through 460 cc includes: a face portion that includes a face surface that is to be a striking surface; and a body portion that includes carbon fiber-reinforced plastics. The body portion includes a sole portion, a crown portion, and a weight member attached to the sole portion at an inner-surface side thereof. The weight member includes a first weight member that is disposed directly below a center of gravity of the golf club head, and a second weight member that extends from the first weight member in a toe-heel direction.

Abstract: The golf club head includes a face portion, a plurality of score lines formed in the face portion and extending in a toe-heel direction, and a plurality of convex portions formed in the face portion, projecting from reference plane which includes edges of each of the plurality of score lines, and extending in the toe-heel direction. The plurality of convex portions include a first convex portion and a second convex portion formed between adjacent score lines. A projecting height of the first convex portion and/or a width in an orthogonal direction of the toe-heel direction of the first convex portion is larger than that of the second convex portion.

Abstract: A golf club head includes a face portion, a plurality of score lines formed in the face portion and extending in a toe-heel direction, a plurality of convex portions formed in the face portion and extending in the toe-heel direction between the score lines adjacent to each other in a vertical direction of the face portion, and at least one concave portion formed in the face portion and extending in the toe-heel direction between the convex portions adjacent to each other in the vertical direction. A flat surface is formed between the concave portion and the convex portion adjacent to the concave portion.

Abstract: A golf club head includes a face portion, a plurality of score lines formed in the face portion and extending in a toe-heel direction, a plurality of convex portions formed in the face portion and extending in the toe-heel direction between the score lines adjacent to each other in a vertical direction of the face portion, and at least one concave portion formed in the face portion and extending in the toe-heel direction between the convex portions adjacent to each other in the vertical direction. A flat surface is formed between the concave portion and the convex portion adjacent to the concave portion.

Abstract: A golf club head includes a face portion, a plurality of score lines formed in the face portion and extending in a toe-heel direction, a plurality of convex portions formed in the face portion and extending in the toe-heel direction between the score lines adjacent to each other in a vertical direction of the face portion, and at least one concave portion formed in the face portion and extending in the toe-heel direction between the convex portions adjacent to each other in the vertical direction. A flat surface is formed between the concave portion and the convex portion adjacent to the concave portion.

Abstract: A cavity back iron type golf club head includes a face portion, a back portion, and at least one reinforcing portion that extends from an upper edge portion of the back portion toward a toe-side portion of a top line.

Abstract: An iron type golf club head includes a face member including a face portion and a back surface opposite to the face portion and a main body member which includes a hosel portion and to which the face member is fixed. A plurality of grooves are formed in the back surface. Each of the plurality of grooves includes a first groove portion which is formed on a leading edge side of the face portion in a height direction and extends continuously in a toe-heel direction over an area not less than a half of a width of the back surface in the toe-heel direction.

Abstract: A golf club head includes a face portion, a plurality of score lines formed in the face portion and extending in a toe-heel direction, a plurality of convex portions formed in the face portion and extending in the toe-heel direction between the score lines adjacent to each other in a vertical direction of the face portion, and at least one concave portion formed in the face portion and extending in the toe-heel direction between the convex portions adjacent to each other in the vertical direction. A flat surface is formed between the concave portion and the convex portion adjacent to the concave portion.

Abstract: A golf club head includes a face portion, a plurality of score lines formed in the face portion and extending in a toe-heel direction, a plurality of convex portions formed in the face portion at intervals in the toe-heel direction, extending in the toe-heel direction, and arranged as a plurality of arrays between the score lines adjacent to each other in a vertical direction of the face portion, and a plurality of concave portions formed in the face portion and extending in a direction, which intersects with the toe-heel direction, while passing between the convex portions adjacent to each other in the toe-heel direction.

Abstract: A golf club head includes a face portion, score lines n the face portion and extending in a toe-heel direction, protruding portions formed on the face portion and extending parallel to the score lines, and recessed portions formed on the face portion and extending parallel to the score lines. Each protruding portion and each recessed portion are formed alternately in a direction orthogonal to the toe-heel direction. The protruding portions include first protruding portions and second protruding portions. Each apex portion of the first protruding portions is positioned in a first imaginary plane parallel to a reference plane that contains each edge of the score lines. Each apex portion of the second protruding portions is positioned in a second imaginary plane parallel to the reference plane and different from the first imaginary plane.

Abstract: A golf club head includes a face, a sole, a back, and a hosel. The back is connected to at least a top blade of the face and to a trailing edge of the sole to form a cavity surrounded by the face, the sole, and the back. The cavity has an opening on a toe side. The sole is shaped into a triangle whose three vertices are a heel end of the sole, a face-side toe end of the sole, and a back-side toe end of the sole. The heel end is a point where a central axis of a bore of the hosel into which a shaft is to be inserted intersects with the sole. The face-side toe end is a point closest to a toe in a region where the sole connects to the face. The back-side toe end is the toe-side end of the trailing edge.

Abstract: A golf club head including a face portion includes a plurality of score lines formed on the face portion, a plurality of first grooves formed on the face portion, and a plurality of second grooves formed on the face portion. The first grooves have a depth D1 and a width W1 that is in a direction orthogonal to a direction in which the first grooves extend, the second grooves have a depth D2 and a width W2 that is in a direction orthogonal to a direction in which the second grooves extend, W1>D1, and W2<D2.

Abstract: A golf club set includes a plurality of golf clubs having different loft angles. The plurality of golf clubs have the same lie angle. Each loft angle difference between two golf clubs that are adjacent in a loft angle order is the same. Each club length difference between two golf clubs that are adjacent in the loft angle order is 0.125 inches (3.175 mm) (inclusive) to 0.375 inches (9.525 mm) (inclusive). A loft angle of a golf club having a minimum frequency is smaller than a loft angle of a golf club having a maximum frequency. A difference between the minimum frequency and the maximum frequency is not less than 40 cpm.

Abstract: A wood type golf club head includes a face portion, a crown portion, and a sole portion. The face portion includes an impact area, a toe-side area on a toe side with respect to the impact area, and a heel-side area on the heel side with respect to the impact area. At least one groove is formed in the toe-side area and/or the heel-side area. The depth of the groove is 0.025 mm (inclusive) to 0.508 mm (inclusive). A groove area occupancy in the toe-side area is different from a groove area occupancy in the heel-side area.

Abstract: A golf club head includes: a crown portion; a sole portion; a face portion; and a hosel portion. The crown portion includes a concave portion that starts from the face portion, passes through a boundary portion of the hosel portion and the crown portion, and extends toward a back side. The concave portion includes a range from the face portion toward the back side where a width of the concave portion is larger than a depth of the concave portion. The range passes on a toe side of the hosel.

Abstract: A golf club head includes a face, a sole, an attachment member, an attachment part, and a rib. The face includes a ball-striking surface. The sole defines the bottom of the golf club head. The attachment member is attachable to the attachment part. The rib is formed on the internal surface of the golf club head, and at least partially surrounds the attachment part.

Abstract: A golf club head includes a crown portion and a face portion. The crown portion includes a first protruding portion arranged on the side of the face portion, and a second protruding portion arranged on the back side to be adjacent to the first protruding portion. The width of the first protruding portion in the face-back direction on a plane passing through the face center of the face portion and extending in the vertical direction is smaller than the width of the second protruding portion in the face-back direction. The protruding height of the second protruding portion is larger than the protruding height of the first protruding portion.

Abstract: A golf club head including a face portion includes a plurality of score lines formed on the face portion, a plurality of first grooves formed on the face portion, and a plurality of second grooves formed on the face portion. The first grooves have a depth D1 and a width W1 that is in a direction orthogonal to a direction in which the first grooves extend, the second grooves have a depth D2 and a width W2 that is in a direction orthogonal to a direction in which the second grooves extend, W1>D1, and W2<D2.

Abstract: A golf club head includes a face portion, score lines n the face portion and extending in a toe-heel direction, protruding portions formed on the face portion and extending parallel to the score lines, and recessed portions formed on the face portion and extending parallel to the score lines. Each protruding portion and each recessed portion are formed alternately in a direction orthogonal to the toe-heel direction. The protruding portions include first protruding portions and second protruding portions. Each apex portion of the first protruding portions is positioned in a first imaginary plane parallel to a reference plane that contains each edge of the score lines. Each apex portion of the second protruding portions is positioned in a second imaginary plane parallel to the reference plane and different from the first imaginary plane.