Patents by Inventor Wataru Hirose

Wataru Hirose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10836146
    Abstract: Provided is a polyvinyl chloride (“PVC”)/ethylene-vinyl alcohol (“EVOH”) multilayer sheet used for the fabrication of liners and covers for the geotechnical industry (“geomembrane”), which sheet has both good flexibility and excellent barrier properties to organic solvents and gases.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: November 17, 2020
    Assignee: KURARAY CO., LTD.
    Inventors: Edgard Chow, Astrid Torres, Wataru Hirose
  • Patent number: 10814596
    Abstract: A silage film having at least one layer of a resin composition containing an ethylene-vinyl alcohol copolymer (A) and a hydroxy group-containing compound (B). In the resin composition containing the ethylene-vinyl alcohol copolymer (A) and the hydroxy group-containing compound (B), the hydroxy group-containing compound (B) has a molecular weight of less than or equal to 200, a ratio of number of hydroxy groups per molecule to the molecular weight ranging from 0.02 to 0.03, and a melting point of greater than or equal to 23° C., and a content of the hydroxy group-containing compound (B) in the resin composition ranging from 3% to 15% by mass. The silage film has excellent oxygen barrier property and stretchability (suitability for wrapping) and can be suitably used for long-term storage of silage.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: October 27, 2020
    Assignee: KURARAY CO., LTD.
    Inventors: Edgard Chow, Wataru Hirose
  • Patent number: 10814350
    Abstract: The composite structural material of the present invention includes a base (X) and a layer (Y) stacked on the base (X). The layer (Y) includes a reaction product (R) of a metal oxide (A) and a phosphorus compound (B). In the infrared absorption spectrum of the layer (Y) in the range of 800 to 1400 cm?1, the wave number (n1) at which the infrared absorption reaches maximum is in the range of 1080 to 1130 cm?1.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: October 27, 2020
    Assignee: KURARAY CO., LTD.
    Inventors: Kentaro Yoshida, Ryoichi Sasaki, Mamoru Omoda, Wataru Hirose, Manabu Shibata, Tatsuya Oshita
  • Patent number: 10815241
    Abstract: The present invention relates to the compound of formula (1a) wherein p is 1 or 2, R1-R4 are hydrogen atom or the like, and a-d are 1 or 2, or a pharmaceutically acceptable salt thereof, which has an antitumor effect by inhibiting the binding between a MLL fusion protein that is infused with AF4, AF9, or the like, which is a representative fusion partner gene causing MLL leukemia, and menin.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: October 27, 2020
    Assignee: Sumitomo Dainippon Pharma Co., Ltd.
    Inventors: Seiji Kamioka, Hitoshi Ban, Naoaki Shimada, Wataru Hirose, Akihiko Arakawa, Kazuto Yamazaki, Kenjiro Hira
  • Patent number: 10683274
    Abstract: The present invention provides a compound of the following Formula (1) or a pharmaceutically acceptable salt thereof: wherein X is an oxygen atom and the like; Y is —CO—, —SO2— and the like; R1 is an optionally-substituted C1-6 alkyl group, an optionally-substituted C1-6 alkylcarbonyl group and the like; R2 is an optionally-substituted C1-6 alkyl group, an optionally-substituted C1-6 alkoxy group, an optionally-substituted amino group, an optionally-substituted 5- to 12-membered monocyclic or polycyclic saturated heterocyclic group and the like; R3, R4, R5, and R6 are independently a hydrogen atom and the like which exhibits excellent effects in suppressing the proliferation and sphere-forming ability of cancer cells, and can be useful as an antitumor drug or cell growth inhibitor.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: June 16, 2020
    Assignee: Boston Biomedical, Inc.
    Inventors: Toshihiko Sone, Wataru Hirose, Naoaki Shimada, Chiang Li, Wei Li, David Leggett
  • Publication number: 20200180279
    Abstract: There is provided a co-injection-molded multilayer structure having a barrier layer and outer layers laminated on both sides of the barrier layer, wherein the barrier layer is made of a resin composition comprising an ethylene-vinyl alcohol copolymer (A) and an alkali metal salt (B) of a higher fatty acid having a melting point of 250° C. or lower; a content of the alkali metal salt (B) in the barrier layer is 50 to 1500 ppm in terms of metal atoms; and the outer layers are made of a resin composition comprising an unmodified polypropylene (E) and a maleic anhydride-modified polypropylene (F) having a lower melt viscosity than that of the unmodified polypropylene (E). Although it has no adhesive layers, the co-injection-molded multilayer structure exhibits excellent adhesiveness between the barrier layer made of an EVOH resin composition and the outer layer made of a polypropylene resin composition.
    Type: Application
    Filed: October 17, 2017
    Publication date: June 11, 2020
    Applicant: KURARAY CO., LTD.
    Inventors: Edgard CHOW, Gene MEDLOCK, Wataru HIROSE
  • Publication number: 20200157114
    Abstract: The present invention relates to the compound of formula (1a) wherein p is 1 or 2, R1-R4 are hydrogen atom or the like, and a-d are 1 or 2, or a pharmaceutically acceptable salt thereof, which has an antitumor effect by inhibiting the binding between a MLL fusion protein that is infused with AF4, AF9, or the like, which is a representative fusion partner gene causing MLL leukemia, and menin.
    Type: Application
    Filed: January 21, 2020
    Publication date: May 21, 2020
    Applicant: Sumitomo Dainippon Pharma Co., Ltd.
    Inventors: Seiji KAMIOKA, Hitoshi BAN, Naoaki SHIMADA, Wataru HIROSE, Akihiko ARAKAWA, Kazuto YAMAZAKI, Kenjiro HIRA
  • Patent number: 10633532
    Abstract: Provided is a resin composition, comprising: an isobutylene-based copolymer (A) containing a halogen atom; an ethylene-vinyl alcohol copolymer (B); and a halogen scavenger (C), wherein a mass ratio (B/A) of the ethylene-vinyl alcohol copolymer (B) to the isobutylene-based copolymer (A) containing a halogen atom is from 20/80 to 50/50, and a content of the halogen scavenger (C) is from 0.01 to 1 part by mass based on 100 parts by mass of a total of the isobutylene-based copolymer (A) containing a halogen atom and the ethylene-vinyl alcohol copolymer (B). Such a resin composition is excellent in gas barrier properties and flexibility and stably produced over a long period of time.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: April 28, 2020
    Assignee: KURARAY CO., LTD.
    Inventors: Wataru Hirose, Takeyuki Igarashi
  • Publication number: 20200087493
    Abstract: A monolayer film is provided which contains ethylene vinyl alcohol copolymer (EVOH), contamination from dirt and a compatibilizer, that can be used for producing trash bags and the like, as well as a method to successfully recycle fumigation films containing EVOH and contamination from dirt into such a monolayer film.
    Type: Application
    Filed: September 12, 2019
    Publication date: March 19, 2020
    Applicant: KURARAY CO., LTD.
    Inventors: Edgard CHOW, Diana Maya, Wataru Hirose
  • Publication number: 20200070483
    Abstract: A multilayer article having at least one layer of an ethylene vinyl alcohol (EVOH) resin composition comprising of an ethylene-vinyl alcohol copolymer, an unmodified ethylene-?-olefin copolymer and acid modified ethylene-?-olefin copolymer as described below, which is suitable for use in making (or as) a storage bag for agricultural products, food, drink, pharmaceutical, cosmetic, industrial chemical, detergent products.
    Type: Application
    Filed: August 28, 2019
    Publication date: March 5, 2020
    Applicant: KURARAY CO., LTD.
    Inventors: Edgard CHOW, Astrid Torres, Wataru Hirose
  • Publication number: 20200048228
    Abstract: Compounds having the following structure (I) or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R1, R2 and R3 are as defined herein, and wherein at least one of R1, R2 and R3 is not H, are provided. Pharmaceutical compositions comprising the compounds and methods for use of the compounds for treating diseases associated with overexpression of a cyclin-dependent kinase (CDK) are also provided.
    Type: Application
    Filed: November 17, 2017
    Publication date: February 13, 2020
    Inventors: Adam Siddiqui-Jain, Yusuke Sawayama, Wataru Hirose, Hitoshi Ban
  • Patent number: 10519303
    Abstract: Provided is a resin composition, comprising: an ethylene-vinyl alcohol copolymer (A); an isobutylene-based copolymer (B) containing a halogen atom; and a halogen scavenger (C), wherein a mass ratio (B/A) of the isobutylene-based copolymer (B) to the ethylene-vinyl alcohol copolymer (A) is from 5/95 to 45/55, and a content of the halogen scavenger (C) is from 0.01 to 1 part by mass based on 100 parts by mass of a total of the ethylene-vinyl alcohol copolymer (A) and the isobutylene-based copolymer (B). Such a resin composition is excellent in gas barrier properties and flexibility and stably produced over a long period of time.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: December 31, 2019
    Assignee: KURARAY CO., LTD.
    Inventors: Takeyuki Igarashi, Wataru Hirose
  • Publication number: 20190367718
    Abstract: Provided is a resin composition containing an ethylene-vinyl alcohol copolymer, a polyamide and a higher fatty acid metal salt, a multilayer structure and a multilayer sheet including the resin composition, and a container and a packaging material including the multilayer sheet. It is particularly concerned with good retort resistance, good thermal stability and good orientability.
    Type: Application
    Filed: May 20, 2019
    Publication date: December 5, 2019
    Applicant: KURARAY CO., LTD.
    Inventor: Wataru HIROSE
  • Publication number: 20190344547
    Abstract: Provided is a polyvinyl chloride (“PVC”)/ethylene-vinyl alcohol (“EVOH”) multilayer sheet used for the fabrication of liners and covers for the geotechnical industry (“geomembrane”), which sheet has both good flexibility and excellent barrier properties to organic solvents and gases.
    Type: Application
    Filed: May 10, 2019
    Publication date: November 14, 2019
    Applicant: KURARAY CO., LTD.
    Inventors: Edgard CHOW, Astrid Torres, Wataru Hirose
  • Publication number: 20190241535
    Abstract: The present invention provides a compound of the following Formula (1) or a pharmaceutically acceptable salt thereof: wherein X is an oxygen atom and the like; Y is —CO—, —SO2— and the like; R1 is an optionally-substituted C1-6 alkyl group, an optionally-substituted C1-6 alkylcarbonyl group and the like; R2 is an optionally-substituted C1-6 alkyl group, an optionally-substituted C1-6 alkoxy group, an optionally-substituted amino group, an optionally-substituted 5- to 12-membered monocyclic or polycyclic saturated heterocyclic group and the like; R3, R4, R5, and R6 are independently a hydrogen atom and the like which exhibits excellent effects in suppressing the proliferation and sphere-forming ability of cancer cells, and can be useful as an antitumor drug or cell growth inhibitor.
    Type: Application
    Filed: November 29, 2018
    Publication date: August 8, 2019
    Inventors: Toshihiko Sone, Wataru Hirose, Naoaki Shimada, Chiang Jiaq Li, Wei Li, David Leggett
  • Publication number: 20190202182
    Abstract: A multilayer article (such as a sheet or bottle) suitable for use as a solvent barrier, the multilayer article comprising at least one an ethylene vinyl alcohol (EVOH) based barrier layer formed from a resin composition predominantly comprising an EVOH component of one or more specific types of ethylene-vinyl alcohol copolymers as described herein.
    Type: Application
    Filed: December 28, 2018
    Publication date: July 4, 2019
    Applicant: KURARAY CO., LTD.
    Inventors: Wataru Hirose, Edgard Chow
  • Publication number: 20190203005
    Abstract: A multilayer article (such as a film) suitable for use as a fumigation barrier, the multilayer article comprising at least one an ethylene vinyl alcohol (EVOH) based barrier layer formed from a resin composition predominantly comprising an EVOH component of one or more specific types of ethylene-vinyl alcohol copolymers as described herein.
    Type: Application
    Filed: December 28, 2018
    Publication date: July 4, 2019
    Applicant: KURARAY CO., LTD.
    Inventors: Wataru Hirose, Edgard Chow
  • Publication number: 20190202181
    Abstract: A multilayer article (such as a film) suitable for use as a gas barrier, the multilayer article comprising at least one an ethylene vinyl alcohol (EVOH) based barrier layer formed from a resin composition predominantly comprising an EVOH component of one or more specific types of ethylene-vinyl alcohol copolymers as described herein.
    Type: Application
    Filed: December 28, 2018
    Publication date: July 4, 2019
    Applicant: KURARAY CO., LTD.
    Inventors: Wataru HIROSE, Edgard CHOW, Robert ARMSTRONG
  • Patent number: 10293968
    Abstract: There is provided a blow-molded container having a pinch-off part and having, as an innermost layer, a layer of resin composition comprising an ethylene-vinyl alcohol copolymer (A) and a soft resin (B), characterized in that the soft resin (B) is a thermoplastic styrenic elastomer or ?-olefinic polymer; a mass ratio of the ethylene-vinyl alcohol copolymer (A) to the soft resin (B) [(A)/(B)] is within the range of 75/25 to 90/10; the resin composition has a matrix and domain structure in which the ethylene-vinyl alcohol copolymer (A) is a matrix phase and the soft resin (B) is a domain phase; and a surface-to-surface interparticle distance in the domain phase is 0.3 ?m or less.
    Type: Grant
    Filed: May 8, 2013
    Date of Patent: May 21, 2019
    Assignee: KURARAY CO., LTD.
    Inventor: Wataru Hirose
  • Patent number: 10246537
    Abstract: A resin composition according to an aspect of the present invention comprises: an ethylene-vinyl alcohol copolymer (A); and a block copolymer (B) having a block (b1) that includes a vinyl aromatic monomer unit, and a block (b2) that includes an isobutylene unit, wherein the ethylene-vinyl alcohol copolymer (A) and the block copolymer (B) form a co-continuous phase structure; and a DSC curve obtained following heating the resin composition up to a melting point and cooling at a rate of 50° C./min in a differential scanning calorimetry analysis shows two peaks, with a higher peak top temperature falling within a range of 130° C. or greater and 170° C. or less, and a lower peak top temperature falling within a range of 100° C. or greater and less than 130° C. A resin composition may thus be obtained that is able to give a molded article that is superior in balance between gas barrier properties and flexibility.
    Type: Grant
    Filed: August 19, 2015
    Date of Patent: April 2, 2019
    Assignee: KURARAY CO., LTD.
    Inventors: Wataru Hirose, Takeyuki Igarashi