Abstract: An elastomeric article having reducing microbe affinity and transmission is disclosed. The article has a coating of a hydrophobic, non-leaching antimicrobial polymer that is durably attached to an exterior surface, such that said antimicrobial polymer does not spontaneously migrate or is not removed from said exterior surface in the presence of aqueous substances, strong acids and bases, and organic solvents, and said antimicrobial polymer forms either a water-insoluable siloxane resin, or a covalently attached siloxane homopolymer, or a combination of both. The coated surface has a reduced affinity for aqueous-based substances and exhibits an enduring reduction in microbe affinity and transmission.