Patents by Inventor Way Xuang LEE
Way Xuang LEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240416335Abstract: Multichannel pipettes, electroporation systems utilizing the multichannel pipettes and methods for electroporating a cell. The electroporation system includes a multichannel pipette, a pipette tip(s), a pipette docking assembly, and a pulse generator. The pipette docking assembly includes a pipette station, a pipette station guard, and a reservoir.Type: ApplicationFiled: June 10, 2024Publication date: December 19, 2024Inventors: Wui Khen Kevin LIAW, Kuan Moon Boo, Huei Steven YEO, Wern Yuh FOO, Joshua Mathew MEAD, Justina Linkai BONG, Mikko MAKINEN, Mio Xiu Lu LING, Way Xuang LEE, Wen Lun CHAN, Yunxiang LIU
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Publication number: 20240263124Abstract: The present disclosure provides electroporation cartridges for single use electroporation as well as electroporation cartridges for automated batch processing, electroporation instruments and systems and methods of electroporation using these devices and systems. In some embodiments, electroporation cartridges comprise an electroporation chamber defined by an elongate body, a first electrode at a proximal end and a second electrode at a distal end of a chamber. Electroporation systems of the disclosure include one or more components including a pulse generator, compartments for placing either flow-through or single use electroporation cartridges, components for storage of cells, cooling and pre-cooling mechanisms, removably insertable modular casings having compartments for holding and arranging electroporation system and reagent components, one or more pumps for moving sample through the system, and processors and controllers.Type: ApplicationFiled: April 2, 2024Publication date: August 8, 2024Inventors: Steven Huei Yeo, Xavier De Mollerat Du Jeu, Way Xuang Lee, Nektaria Andronikou, Benyong Shi, Kok Shyong Chong, Han Wei, Siu Wee Hon, Yvonne Peck, Chee Wai Chan, Beng Heng Lim, Stacey Mei Lin Teo, Dhanaraj Shanmugam, Jun Yan Tham, Michael Gordon, Chris Rossman, Ulrich Forke, Li Yang Lim
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Publication number: 20240150699Abstract: An electroporation system including one or more of a pipette, a pipette tip, a pipette docking assembly, and a pulse generator. The pipette docking assembly includes a pipette station, a pipette station guard, and a reservoir (e.g., a buffer tube). A method for transfecting a cell with a payload including providing an electroporation system, providing the cell, providing the payload, introducing the cell and the payload into a pipette tip, and electroporating the cell within the pipette tip by operating the electroporation system.Type: ApplicationFiled: September 15, 2023Publication date: May 9, 2024Inventors: Han WEI, Chee Wai CHAN, Wui Khen LIAW, Shan Hua DONG, See Chen GOH, Huei Steven YEO, Harmon Cosme SICAT, JR., Mio Xiu Lu LING, Josh M. MEAD, Mikko MAKINEN, Beng Heng LIM, Kuan Moon BOO, Justina Linkai BONG, Chye Sin NG, Wee Liam LIM, Li Yang LIM, Way Xuang LEE
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Publication number: 20210123009Abstract: The present disclosure provides electroporation cartridges for single use electroporation as well as electroporation cartridges for automated batch processing, electroporation instruments and systems and methods of electroporation using these devices and systems. In some embodiments, electroporation cartridges comprise an electroporation chamber defined by an elongate body, a first electrode at a proximal end and a second electrode at a distal end of a chamber. Electroporation systems of the disclosure include one or more components including a pulse generator, compartments for placing either flow-through or single use electroporation cartridges, components for storage of cells, cooling and pre-cooling mechanisms, removably insertable modular casings having compartments for holding and arranging electroporation system and reagent components, one or more pumps for moving sample through the system, and processors and controllers.Type: ApplicationFiled: October 23, 2020Publication date: April 29, 2021Inventors: Steven Huei YEO, Siu Wee HON, Han WEI, Yvonne PECK, Way Xuang LEE, Benyong SHI, Chee Wai CHAN, Beng Heng (Derrick) LIM, Dhanaraj SHANMUGAM, Stacey TEO, Jun Yan THAM, Kok Shyong CHONG, Li Yang LIM, Michael GORDON, Nektaria ANDRONIKOU, Chris ROSSMANN, Xavier DE Mollerat DU JEU, Ulrich FORKE
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Patent number: 10835901Abstract: A thermal block assembly including a sample block and two or more thermoelectric devices, is disclosed. The sample block has a top surface configured to receive a plurality of reaction vessels and an opposing bottom surface. The thermoelectric devices are operably coupled to the sample block, wherein each thermoelectric device includes a housing for a thermal sensor and a thermal control interface with a controller. Each thermoelectric device is further configured to operate independently from each other to provide a substantially uniform temperature profile throughout the sample block.Type: GrantFiled: June 30, 2017Date of Patent: November 17, 2020Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Hon Siu Shin, Chin Yong Koo, Way Xuang Lee, Chee Kiong Lim, Chee Wee Ching, Niroshan Ramachandran
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Publication number: 20200101461Abstract: In one aspect, a thermal cycler system including a sample block and a thermoelectric device is disclosed. In various embodiments, the sample block has a first surface configured to receive a plurality of reaction vessels and an opposing second surface. In various embodiments the thermoelectric device is operably coupled to the second surface of the sample block. In various embodiments a thermal control unit is provided. In various embodiments the thermal control unit includes a computer processing unit. In various embodiments the thermal control unit includes an electrical current source. In various embodiments the thermal control unit also includes an electrical interface portion configured to connect the thermoelectric device with the electrical current source by way of an electrical cable. In various embodiments the thermal control unit is oriented in a different plane than the sample block and thermoelectric cooler.Type: ApplicationFiled: September 26, 2019Publication date: April 2, 2020Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Chee Kiong LIM, Way Xuang LEE, Wuh Ken LOH, Chee Wee CHING, Chin Yong KOO, Siew Ying KOH, Tiong Han TOH, Kuan Moon BOO, Soo Yong LAU
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Patent number: 10471431Abstract: In one aspect, a thermal cycler system including a sample block and a thermoelectric device is disclosed. In various embodiments, the sample block has a first surface configured to receive a plurality of reaction vessels and an opposing second surface. In various embodiments the thermoelectric device is operably coupled to the second surface of the sample block. In various embodiments a thermal control unit is provided. In various embodiments the thermal control unit includes a computer processing unit. In various embodiments the thermal control unit includes an electrical current source. In various embodiments the thermal control unit also includes an electrical interface portion configured to connect the thermoelectric device with the electrical current source by way of an electrical cable. In various embodiments the thermal control unit is oriented in a different plane than the sample block and thermoelectric cooler.Type: GrantFiled: February 4, 2015Date of Patent: November 12, 2019Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Chee Kiong Lim, Way Xuang Lee, Wuh Ken Loh, Chee Wee Ching, Chin Yong Koo, Siew Ying Koh, Tiong Han Toh, Kuan Moon Boo, Soo Yong Lau
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Publication number: 20190126281Abstract: A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray comprising a slide assembly, the tray configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.Type: ApplicationFiled: August 29, 2018Publication date: May 2, 2019Inventors: Yong CHU, Jeffrey MARKS, Jacob FREUDENTHAL, Mingsong CHEN, Tiong Han TOH, Mauro AGUANNO, Lik Seng LAU, Lian Seng LOH, Kok Siong TEO, Zeng Wei CHU, Xin MATHERS, Michael UY, Huei Steven YEO, Kuan Moon BOO, Way Xuang LEE, Chin Yong KOO, Wei Fuh TEO, Soo Yong LAU, Hon Siu SHIN, Zeqi TAN, Thomas WESSEL, David WOO
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Publication number: 20180056296Abstract: A thermal block assembly including a sample block and two or more thermoelectric devices, is disclosed. The sample block has a top surface configured to receive a plurality of reaction vessels and an opposing bottom surface. The thermoelectric devices are operably coupled to the sample block, wherein each thermoelectric device includes a housing for a thermal sensor and a thermal control interface with a controller. Each thermoelectric device is further configured to operate independently from each other to provide a substantially uniform temperature profile throughout the sample block.Type: ApplicationFiled: June 30, 2017Publication date: March 1, 2018Inventors: Hon Siu SHIN, Chin Yong KOO, Way Xuang LEE, Chee Kiong LIM, Chee Wee CHING, Niroshan RAMACHANDRAN
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Publication number: 20160228876Abstract: A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray comprising a slide assembly, the tray configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.Type: ApplicationFiled: February 5, 2016Publication date: August 11, 2016Inventors: Yong Chu, Jeffrey Marks, Jacob Freudenthal, Mingsong Chen, Tiong Han Toh, Mauro Aguanno, Lik Seng Lau, Lian Seng Loh, Kok Siong Teo, Zeng Wei Chu, Xin Mathers, Michael Uy, Huei Yeo, Kuan Moon Boo, Way Xuang Lee, Chin Yong Koo, Wei Fuh Teo, Soo Yong Lau, Hon Siu Shin, Zeqi Tan, Thomas Wessel, Woo David
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Publication number: 20160214110Abstract: A thermal block assembly including a sample block and two or more thermoelectric devices, is disclosed. The sample block has a top surface configured to receive a plurality of reaction vessels and an opposing bottom surface. The thermoelectric devices are operably coupled to the sample block, wherein each thermoelectric device includes a housing for a thermal sensor and a thermal control interface with a controller. Each thermoelectric device is further configured to operate independently from each other to provide a substantially uniform temperature profile throughout the sample block.Type: ApplicationFiled: September 15, 2014Publication date: July 28, 2016Inventors: Hon Siu SHIN, Chin Yong KOO, Way Xuang LEE, Chee Kiong LIM, Chee Wee CHING, Niroshan RAMACHANDRAN
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Publication number: 20150231636Abstract: In one aspect, a thermal cycler system including a sample block and a thermoelectric device is disclosed. In various embodiments, the sample block has a first surface configured to receive a plurality of reaction vessels and an opposing second surface. In various embodiments the thermoelectric device is operably coupled to the second surface of the sample block. In various embodiments a thermal control unit is provided. In various embodiments the thermal control unit includes a computer processing unit. In various embodiments the thermal control unit includes an electrical current source. In various embodiments the thermal control unit also includes an electrical interface portion configured to connect the thermoelectric device with the electrical current source by way of an electrical cable. In various embodiments the thermal control unit is oriented in a different plane than the sample block and thermoelectric cooler.Type: ApplicationFiled: February 4, 2015Publication date: August 20, 2015Inventors: Chee Kiong Lim, Way Xuang LEE, Wuh Ken LOH, Chee Wee CHING, Chin Yong KOO, Siew Ying KOH, Tiong Han TOH, Kuan Moon BOO, Soo Yong LAU
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Patent number: D774206Type: GrantFiled: January 22, 2016Date of Patent: December 13, 2016Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Kuan Moon Boo, Way Xuang Lee, Wuh Ken Loh, Zeqi Tan, Sandro Klein
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Patent number: D822847Type: GrantFiled: November 21, 2016Date of Patent: July 10, 2018Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Kuan Moon Boo, Way Xuang Lee, Wuh Ken Loh, Zeqi Tan, Sandro Klein