Abstract: Introduced here are approaches to simulating the actions of, and interactions between, biological systems in target environments through the use of computational workflows. These actions may relate to natural processes and novel adaptations (e.g., introduced through genetic engineering). At a high level, the computational workflows described herein provide a framework for efficient data management, thereby allowing increased productivity. While simplified approaches to user input are one feature highlighted in the present disclosure, the computational workflows described herein may also allow modification of parameters for any or all software modules in the workflow.