Abstract: A shapeable, weather-resistant anti-slip panel has a cut-resistant anti-slip coating on a rigid substrate and a pattern of cuttable lines; this enables the panel to be shaped by cutting the substrate along selected lines and overcomes the problem with known weather resistant anti-slip panels that the anti-slip coating particles, being very hard, make the anti-slip coating very difficult to cut or drill, as the coating readily and speedily blunts cutting tools.

Abstract: The present invention relates to methods for determining and predicting the efficacy of therapeutics for the treatment of an individual with asthma based on that individual's ?2-adrenergic receptor. The invention finds particular applicability to the treatment of an individual with asthma with an inhaled corticosteroid or a leukotriene receptor antagonist who is homozygous for arginine at position 16 of the ?2-adrenergic receptor.

Abstract: A system is provided for sensing blood glucose data of a patient. The system includes a sensor, user interface, and an optional auxiliary device. If the connection between the sensor and user interface is by a wire, the sensor remains powered when the wire is disconnected. The communication between the sensor and the user interface may be wireless. The auxiliary device can be a patient monitor or other display or signal device, which displays information about the blood glucose data collected by the sensor. The sensor is connected to sensor electronics, which include a sensor power supply, a voltage regulator, and optionally a memory and processor.

Abstract: A system, method and program are disclosed for achieving rapid bit synchronization in low power medical device systems. Messages are transmitted via telemetry between a medical device and a communication device. The synchronization scheme uses a portion of a unique preamble bit pattern to identify the communication device allowing for economical communications with a minimum expenditure of energy. A special set of preamble bit patterns are utilized for their unique synchronization properties making them particularly suited for rapid bit synchronization. These unique preamble bit patterns further provide simplification to the preamble error detection logic.

Abstract: A programmable telemetry circuit that may be programmed for high bandwidth, low Q; low bandwidth, high Q; or for other parameters. The programmable telemetry circuit may include a first coil; a high impedance path having a first node connected to a first node of the first coil; a low impedance path having a first node connected to the first node of the first coil; a capacitive path having a first node connected to a second node of the first coil; and an input path for coupling signals into the high impedance path, the low impedance path, and the capacitive path. The low impedance path may be connected in parallel with the high impedance path. The capacitive path may form a circuitous path with the high impedance path and the low impedance path. The programmable circuit may be programmed to select the high impedance path or the low impedance path.

Abstract: A system and method for multiple antennas on a single core. The system may include a first core, a first winding wound about the first core for transmitting/receiving electromagnetic signals, and a second winding for transmitting/receiving electromagnetic signals wound about the first core and the first winding. The first winding and the second winding may be wound such that a direction of a first magnetic field generated by the first winding is different than a direction of a second magnetic field generated by the second winding. The system may also include activation circuitry connected to the first winding and the second winding. The activation circuitry may activate the first winding separately from the second winding. The system may be expanded to three or more coils/antennas disposed on a single core.

Abstract: An electronic circuit for sensing an output of a sensor having at least one electrode pair and circuitry for obtaining and processing the sensor output. The electrode pair may be laid out such that one electrode is wrapped around the other electrode in a U-shaped fashion. The electronic circuitry may include, among other things, a line interface for interfacing with input/output lines, a rectifier in parallel with the line interface, a counter connected to the line interface and a data converter connected to the counter and the electrode pair. The data converter may be a current-to-frequency converter. In addition, the rectifier may derive power for the electronic circuit from communication pulses received on the input/output lines.

Abstract: A variable resistance physical exercise apparatus is provided which provides improved features over prior art devices in that it is more compact, provides a linear resistance profile to the user and provides a variety of modes of operation. The device comprises a motor driven bi-directional linear translation mechanism to vary the effective length of a lever arm and therefore vary the weight of resistance to the user. An alternative embodiment includes a spring winder drum pulley combination.

Abstract: An electronic circuit for sensing an output of a sensor having at least one electrode pair and circuitry for obtaining and processing the sensor output. The electrode pair may be laid out such that one electrode is wrapped around the other electrode in a U-shaped fashion. The electronic circuitry may include, among other things, a line interface for interfacing with input/output lines, a rectifier in parallel with the line interface, a counter connected to the line interface and a data converter connected to the counter and the electrode pair. The data converter may be a current-to-frequency converter. In addition, the rectifier may derive power for the electronic circuit from communication pulses received on the input/output lines.

Abstract: A communication device (CD) exchanges messages with an implantable infusion pump via telemetry such that commands are supplied thereto and operational information is obtained therefrom. The CD is controlled, at least in part, by a processor IC according to a software program operating therein and provides feedback to a user via a visual display, an audio alarm, and a vibrational alarm, and allows input from the user via a touch sensitive keypad. Certain input functions are restricted by password. The visual display includes an icon and fixed element display region and a bitmap display region. The fixed element display region includes time and date displays, battery and drug level displays that decrement, and a moving delivery state display. Various screens allow operational or log information to be displayed and/or user entry of commands. Program features when disabled are removed from a series of screen options that can be scrolled through.

Abstract: A relay device transfers information between a sensor system, which measures a physiological characteristic level of a user, and a fluid delivery system, which infuses a fluid into a user. The relay device includes a sensor system receiver for receiving communications from the sensor system in a sensor system format. The relay device also includes a processor for processing the communications from the sensor system and converting the communications for transmission in a delivery system format. The relay device further includes a delivery system transmitter for transmitting the converted communications in the delivery system format to the fluid delivery system. The sensor system and delivery system formats may utilize different frequencies and/or different communication protocols for communications transmitted between the sensor system and the fluid delivery system through the relay device.

Abstract: A communication device (CD) exchanges messages with an implantable infusion pump via telemetry such that commands are supplied thereto and operational information is obtained therefrom. The CD is controlled, at least in part, by a processor IC according to a software program operating therein and provides feedback to a user via a visual display, an audio alarm, and a vibrational alarm, and allows input from the user via a touch sensitive keypad. Certain input functions are restricted by password. The visual display includes an icon and fixed element display region and a bitmap display region. The fixed element display region includes time and date displays, battery and drug level displays that decrement, and a moving delivery state display. Various screens allow operational or log information to be displayed and/or user entry of commands. Program features when disabled are removed from a series of screen options that can be scrolled through.

Abstract: An implantable infusion pump possesses operational functionality that is, at least in part, controlled by software operating in two processor ICs which are configured to perform some different and some duplicate functions. The pump exchanges messages with an external device via telemetry. Each processor controls a different part of the drug infusion mechanism such that both processors must agree on the appropriateness of drug delivery for infusion to occur. Delivery accumulators are incremented and decremented with delivery requests and with deliveries made. When accumulated amounts reach or exceed, quantized deliverable amounts, infusion is made to occur. The accumulators are capable of being incremented by two or more independent types of delivery requests. Operational modes of the infusion device are changed automatically in view of various system errors that are trapped, various system alarm conditions that are detected, and when excess periods of time lapse between pump and external device interactions.

Abstract: An implantable infusion pump possesses operational functionality that is, at least in part, controlled by software operating in two processor ICs which are configured to perform some different and some duplicate functions. The pump exchanges messages with an external device via telemetry. Each processor controls a different part of the drug infusion mechanism such that both processors must agree on the appropriateness of drug delivery for infusion to occur. Delivery accumulators are incremented and decremented with delivery requests and with deliveries made. When accumulated amounts reach or exceed, quantized deliverable amounts, infusion is made to occur. The accumulators are capable of being incremented by two or more independent types of delivery requests. Operational modes of the infusion device are changed automatically in view of various system errors that are trapped, various system alarm conditions that are detected, and when excess periods of time lapse between pump and external device interactions.

Abstract: An electronic circuit for sensing an output of a sensor having at least one electrode pair and circuitry for obtaining and processing the sensor output. The electrode pair may be laid out such that one electrode is wrapped around the other electrode in a U-shaped fashion. The electronic circuitry may include, among other things, a line interface for interfacing with input/output lines, a rectifier in parallel with the line interface, a counter connected to the line interface and a data converter connected to the counter and the electrode pair. The data converter may be a current-to-frequency converter. In addition, the rectifier may derive power for the electronic circuit from communication pulses received on the input/output lines.

Abstract: A communication device (CD) exchanges messages with an implantable infusion pump via telemetry such that commands are supplied thereto and operational information is obtained therefrom. The CD is controlled, at least in part, by a processor IC according to a software program operating therein and provides feedback to a user via a visual display, an audio alarm, and a vibrational alarm, and allows input from the user via a touch sensitive keypad. Certain input functions are restricted by password. The visual display includes an icon and fixed element display region and a bitmap display region. The fixed element display region includes time and date displays, battery and drug level displays that decrement, and a moving delivery state display. Various screens allow operational or log information to be displayed and/or user entry of commands. Program features when disabled are removed from a series of screen options that can be scrolled through.

Abstract: A protection device for use in an implantable medical device such as an ICD that communicates with an external programmer. The protection device includes one or more control blocks that inhibit gate triggers for the switching elements (IGBTs) of an H-bridge whenever the drive voltage for these switching elements falls below a pre-determined level. Each control block provides a controlled path to charge the IGBT gate when triggering is required and, importantly, when the gate drive voltage is above a predetermined threshold. The control block further prevents inadvertent or spurious triggering and protects the gate circuitry of the switching elements by providing a low impedance path between the gates and sources of the IGBTs when the latter switching elements are intended to be turned OFF. Additionally, the control blocks protect the IGBTs from over-voltage effects by clamping the output of the gate trigger with a shunt regulator circuit.

Abstract: A shapeable, weather-resistant anti-slip panel has a cut-resistant anti-slip coating on a rigid substrate and a pattern of cuttable lines; this enables the panel to be shaped by cutting the substrate along selected lines and overcomes the problem with known weather resistant anti-slip panels that the anti-slip coating particles, being very hard, make the anti-slip coating very difficult to cut or drill, as the coating readily and speedily blunts cutting tools.

Abstract: A protection device for use in an implantable medical device such as an ICD that communicates with an external programmer. The protection device includes one or more control blocks that inhibit gate triggers for the switching elements (IGBTs) of an H-bridge whenever the drive voltage for these switching elements falls below a pre-determined level. Each control block provides a controlled path to charge the IGBT gate when triggering is required and, importantly, when the gate drive voltage is above a predetermined threshold. The control block further prevents inadvertent or spurious triggering and protects the gate circuitry of the switching elements by providing a low impedance path between the gates and sources of the IGBTs when the latter switching elements are intended to be turned OFF. Additionally, the control blocks protect the IGBTs from over-voltage effects by clamping the output of the gate trigger with a shunt regulator circuit.

Abstract: An implantable infusion pump possesses operational functionality that is, at least in part, controlled by software operating in two processor ICs which are configured to perform some different and some duplicate functions. The pump exchanges messages with an external device via telemetry. Each processor controls a different part of the drug infusion mechanism such that both processors must agree on the appropriateness of drug delivery for infusion to occur. Delivery accumulators are incremented and decremented with delivery requests and with deliveries made. When accumulated amounts reach or exceed, quantized deliverable amounts, infusion is made to occur. The accumulators are capable of being incremented by two or more independent types of delivery requests. Operational modes of the infusion device are changed automatically in view of various system errors that are trapped, various system alarm conditions that are detected, and when excess periods of time lapse between pump and external device interactions.