Abstract: A tissue retractor for retracting tissue opened by an incision, the tissue retractor including a base support unit having a topside and an underside. The topside has at least one securing mechanism and the underside is conformable and removably attachable to a surface proximate to the incision. The tissue retractor has a tissue hook having a tissue engagement portion and a mounting portion, the tissue engagement portion capable of engaging at least the periphery of the incision. The tissue retractor has a retractable member substantially inelastic in its central longitudinal axis and bendable in any axes deviating from the central longitudinal axis. The retractable member receives the mounting portion of the tissue hook, the retractable member being removably attachable to said securing mechanism on the topside of the base support unit, and being retractable away from the incision, such that the tissue engagement portion retracts tissue engaged thereto.

Abstract: A tissue retractor for retracting tissue opened by an incision, said tissue retractor including a base support unit having a topside and an underside. The topside comprises at least one securing mechanism and the underside is adapted to be conformable and to be removably attachable to a surface proximate to the incision. The tissue retractor also includes at least one tissue hook having a tissue engagement portion and a mounting portion, wherein the tissue engagement portion is capable of engaging at least the periphery of the incision. The tissue retractor also includes at least one retractable member substantially inelastic in its central longitudinal axis and bendable in any axes deviating from said central longitudinal axis.

Abstract: A fluid circuit for circulating coolant in a closed loop between an intravascular catheter and a heat exchange system includes a buffer IV bag in fluid flow series with the catheter between the catheter and a pump that pumps the coolant to the heat exchange system. A conventional IV bag is connected by means of a spike and tube to the buffer bag.

Abstract: Various types of insulated coolant lines that extend between a heat exchanger and an intravascular heat exchange catheter are disclosed.

Abstract: A portable cooler is provided for heat exchange catheters that is powered by one or more batteries. The cooler can include Rankine cycle compressor components or thermoelectric cooler (TEC) components. The cooler can be carried in an ambulance and used to support coolant to an indwelling heat exchange catheter that is placed in the patient's venous system to prevent fever and/or induce therapeutic moderate hypothermia in, e.g., stroke victims, heart attack victims, and cardiac arrest victims.

Abstract: Various types of insulated coolant lines that extend between a heat exchanger and an intravascular heat exchange catheter are disclosed.

Abstract: Plural coolant inlet holes are provided into a balloon of a closed loop intravascular cooling catheter to increase the effective surface area of the balloon available for heat exchange. The coolant may be a mixture of water and ethanol.

Abstract: A system and method for treating a patient by inducing therapeutic hypothermia in the patient using an intravascular heat exchange catheter in conjunction with infusing tissue preservative substances into the patient.

Abstract: A fluid circuit for circulating coolant in a closed loop between an intravascular catheter and a heat exchange system includes a buffer IV bag in fluid flow series with the catheter between the catheter and a pump that pumps the coolant to the heat exchange system. A conventional IV bag is connected by means of a spike and tube to the buffer bag.

Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and a variable speed DC compressor for removing heat from the refrigerant. A coolant pump circulates the heating/cooling fluid between the heat exchanger and the heat exchange bath.

Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and a variable speed DC compressor for removing heat from the refrigerant. A coolant pump circulates the heating/cooling fluid between the heat exchanger and the heat exchange bath.

Abstract: A heat exchanger to remove heat from coolant in a closed circuit cooling catheter includes two heat exchange stages. Each stage includes a heat exchange element, such as a group of hollow fibers, and a TEC array juxtaposed with the heat exchange element to remove heat from the element. The elements are in fluid series with each other and are separated from each other by a thermal barrier. A thermal interface can be provided between each element and its TEC array. In one embodiment, the thermal interface is a gel layer. In another embodiment, the thermal interface is an ethylene glycol bath.

Abstract: A heat exchanger to remove heat from coolant in a closed circuit cooling catheter includes two heat exchange stages. Each stage includes a heat exchange element, such as a group of hollow fibers, and a TEC array juxtaposed with the heat exchange element to remove heat from the element. The elements are in fluid series with each other and are separated from each other by a thermal barrier. A thermal interface can be provided between each element and its TEC array. In one embodiment, the thermal interface is a gel layer. In another embodiment, the thermal interface is an ethylene glycol bath.