Patents by Inventor Wayne C. Gatlin

Wayne C. Gatlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SIALIDASE-HER2-ANTIBODY FUSION PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20220387616
    Abstract: The invention relates generally to recombinant sialidase and anti-HER2 immunoglobulin antigen-binding domain fusion proteins. The invention also provides antibody conjugates including a sialidase and an anti-HER2 antibody or a portion thereof. The invention further relates to methods of using the sialidase fusion proteins or antibody conjugates for treating cancer.
    Type: Application
    Filed: July 3, 2020
    Publication date: December 8, 2022
    Inventors: Li Peng, Lizhi Cao, Wayne C. Gatlin, Weiguo Yao, Zakir B. Siddiquee, Sujata B. Nerle, Jenny Che
  • SIALIDASE-CD20-ANTIBODY FUSION PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20220380742
    Abstract: The invention relates generally to recombinant sialidase and anti-CD20 immunoglobulin antigen-binding domain fusion proteins. The invention also provides antibody conjugates including a sialidase and an anti-CD20 antibody or a portion thereof. The invention further relates to methods of using the sialidase fusion proteins or antibody conjugates for treating cancer.
    Type: Application
    Filed: July 3, 2020
    Publication date: December 1, 2022
    Inventors: Li Peng, Sujata B. Nerle, Wayne C. Gatlin
  • RECOMBINANT SIALIDASES AND METHODS OF USING THE SAME
    Publication number: 20220362351
    Abstract: The invention relates generally to recombinant sialidases, methods and compositions for extending the serum half-life of the recombinant sialidases, and use of the same in the treatment of a sialic acid-related disorder.
    Type: Application
    Filed: July 3, 2020
    Publication date: November 17, 2022
    Inventors: Li Peng, Lizhi Cao, Sandip A. Shelke, Andrew S. Turner, Lihui Xu, Wayne C. Gatlin, James W. Broderick, Karl D. Normington, Sujata B. Nerle, Zakir B. Siddiquee, Abhishek Das