Patents by Inventor Wayne Childers

Wayne Childers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11844541
    Abstract: A cooling tower for evaporative cooling of water is contained within an ISO-compliant shipping container frame, permitting stacking of cooling towers for transport and for certain industrial applications. A volume of fill media is contained within the frame. Spaced apart troughs underlie the fill media, running substantially the length of the fill media and connecting to a basin. Baffles are connected to one upper edge of the troughs, while an air flow space is positioned over the other upper trough edge. A water distribution system, with variable flow nozzles positioned closely above the fill media, sprays water over the upper surface of the fill media, where it moves by gravity down into the troughs. Fans atop the fill media move air vertically upward through the fill media.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: December 19, 2023
    Assignee: AGGREKO, LLC
    Inventors: Billy Wayne Childers, Jr., Atul Amar Kumar Swamy
  • Publication number: 20190380821
    Abstract: Systems and method for delivery and positioning of a sheet-like surgical implant to a target site including a means of deploying and orienting the sheet-like implant within body.
    Type: Application
    Filed: February 2, 2018
    Publication date: December 19, 2019
    Inventors: Billy Wayne CHILDERS, JR., Atul Amar Kumar SWAMY
  • Patent number: 10131637
    Abstract: Disclosed are compounds of the class of 2-phenylacetamides that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), and methods of using these modulators to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: November 20, 2018
    Assignees: Shifa Biomedical Corporation, Temple University—Of The Commonwealth System of Higher Education
    Inventors: Sherin Salaheldin Abdel-Meguid, Magid Abou-Gharbia, Benjamin Blass, Wayne Childers, Nabil Elshourbagy, Victor Ghidu, Rogelio Martinez, Harold Meyers, Shaker A. Mousa
  • Patent number: 10028931
    Abstract: Synergistic pharmaceutical compositions including an RNase P inhibitor and a tRNA synthetase inhibitor are provided, as well as methods for their use in treating infections. Also provided herein are methods of using the compositions to inhibit a bacterial tRNA synthetase in a cell and to decolonize bacteria on a surface.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: July 24, 2018
    Assignees: University of Rochester, Temple University—Of the Commonwealth System of Higher Education
    Inventors: Paul M. Dunman, Wayne Childers
  • Publication number: 20180079730
    Abstract: Disclosed are compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), and methods of using these modulators to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia.
    Type: Application
    Filed: December 1, 2017
    Publication date: March 22, 2018
    Inventors: Sherin Salaheldin Abdel-Meguid, Magid Abou-Gharbia, Benjamin Blass, Wayne Childers, Nabil Elshourbagy, Victor Ghidu, Rogelio Martinez, Harold Meyers, Shaker A. Mousa
  • Publication number: 20170246139
    Abstract: Synergistic pharmaceutical compositions including an RNase P inhibitor and a tRNA synthetase inhibitor are provided, as well as methods for their use in treating infections. Also provided herein are methods of using the compositions to inhibit a bacterial tRNA synthetase in a cell and to decolonize bacteria on a surface.
    Type: Application
    Filed: October 30, 2015
    Publication date: August 31, 2017
    Applicants: UNIVERSITY OF ROCHESTER, TEMPLE UNIVERSITY -- OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Paul M. Dunman, Wayne Childers
  • Patent number: 9693999
    Abstract: Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease. Also described herein are methods of identifying compounds for treating or preventing a microbial infection.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: July 4, 2017
    Assignees: University of Rochester, Board of Regents of the University of Nebraska, Temple University—Of the Commonwealth System of Higher Education
    Inventors: Paul M. Dunman, Patrick D. Olson, Wayne Childers
  • Patent number: 9517230
    Abstract: Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: December 13, 2016
    Assignees: UNIVERSITY OF ROCHESTER, BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA, TEMPLE UNIVERSITY—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Paul M. Dunman, Patrick D. Olson, Wayne Childers
  • Publication number: 20160115124
    Abstract: Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease. Also described herein are methods of identifying compounds for treating or preventing a microbial infection.
    Type: Application
    Filed: November 5, 2015
    Publication date: April 28, 2016
    Applicants: UNIVERSITY OF ROCHESTER, BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA, TEMPLE UNIVERSITY -- OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Paul M. Dunman, Patrick D. Olson, Wayne Childers
  • Patent number: 9233095
    Abstract: Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease. Also described herein are methods of identifying compounds for treating or preventing a microbial infection.
    Type: Grant
    Filed: January 26, 2012
    Date of Patent: January 12, 2016
    Assignees: University of Rochester, Board of Regents of the University of Nebraska, Temple University—Of the Commonwealth System of Higher Education
    Inventors: Paul M. Dunman, Patrick D. Olson, Wayne Childers
  • Publication number: 20150376139
    Abstract: Disclosed are compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), and methods of using these modulators to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia.
    Type: Application
    Filed: March 11, 2014
    Publication date: December 31, 2015
    Inventors: Sherin Salaheldin Abdel-Meguid, Magid Abou-Gharbia, Benjamin Blass, Wayne Childers, Nabil Elshourbagy, Victor Ghidu, Rogelio Martinez, Harold Meyers, Shaker A. Mousa
  • Publication number: 20150283118
    Abstract: Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease.
    Type: Application
    Filed: June 19, 2015
    Publication date: October 8, 2015
    Applicants: UNIVERSITY OF ROCHESTER, BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA, TEMPLE UNIVERSITY -- OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Paul M. Dunman, Patrick D. Olson, Wayne Childers
  • Patent number: 9089545
    Abstract: Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease.
    Type: Grant
    Filed: January 26, 2012
    Date of Patent: July 28, 2015
    Assignees: University of Rochester, Board of Regents of the University of Nebraska, Temple University—Of the Commonwealth System of Higher Education
    Inventors: Paul M. Dunman, Patrick D. Olson, Wayne Childers
  • Patent number: 8585024
    Abstract: A water cooling tower having an improved water collection system. The cooling tower has an outer shell, legs, and one or more layers of fill material, through which the water to be cooled moves vertically downward. The water is distributed across the upper surface of the fill material by piping and nozzles. A fan underlying the fill material moves air vertically upward through the fill material. The water collection system, which is positioned below the fill material, has upper and lower troughs which receive water flowing vertically downward through the fill material. Preferably, the lower troughs are positioned beneath the spaces between upper troughs, to catch water falling between the upper troughs. A number of hinged baffles close off the spaces between lower troughs, but rotate upward in response to upward air flow and open the spaces between the lower troughs.
    Type: Grant
    Filed: August 23, 2010
    Date of Patent: November 19, 2013
    Assignee: Aggreko, LLC
    Inventors: David Alan Ferree, Billy Wayne Childers, Jr.
  • Publication number: 20130303585
    Abstract: Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease. Also described herein are methods of identifying compounds for treating or preventing a microbial infection.
    Type: Application
    Filed: January 26, 2012
    Publication date: November 14, 2013
    Applicants: UNIVERSITY OF ROCHESTER, TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER LEARNING, BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventors: Paul M. Dunman, Patrick D. Olson, Wayne Childers
  • Publication number: 20130296386
    Abstract: Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease.
    Type: Application
    Filed: January 26, 2012
    Publication date: November 7, 2013
    Applicants: UNIVERSITY OF ROCHESTER, TEMPLE UNIVERSITY--OF THE COMMONWEALTH SYSTEM OF HIGHER LEARNING, BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventors: Paul M. Dunman, Patrick D. Olson, Wayne Childers
  • Publication number: 20110049733
    Abstract: A water cooling tower having an improved water collection system. The cooling tower has an outer shell, legs, and one or more layers of fill material, through which the water to be cooled moves vertically downward. The water is distributed across the upper surface of the fill material by piping and nozzles. A fan underlying the fill material moves air vertically upward through the fill material. The water collection system, which is positioned below the fill material, has upper and lower troughs which receive water flowing vertically downward through the fill material. Preferably, the lower troughs are positioned beneath the spaces between upper troughs, to catch water falling between the upper troughs. A number of hinged baffles close off the spaces between lower troughs, but rotate upward in response to upward air flow and open the spaces between the lower troughs.
    Type: Application
    Filed: August 23, 2010
    Publication date: March 3, 2011
    Applicant: AGGREKO LLC
    Inventors: David Alan Ferree, Billy Wayne Childers, JR.
  • Publication number: 20080070925
    Abstract: Methods and compositions are provided for treating sexual dysfunction, e.g., sexual dysfunction associated with drug treatment, using 5-HT1A receptor antagonists.
    Type: Application
    Filed: August 20, 2007
    Publication date: March 20, 2008
    Inventors: Stacey SUKOFF RIZZO, Sharon ROSENZWEIG-LIPSON, Wayne CHILDERS, Michael KELLY, Lee SCHECHTER
  • Publication number: 20070270587
    Abstract: Novel pyrimidoindolone compounds are disclosed. Methods of using the pyrimidoindolone compounds and compositions containing the compounds in the treatment and/or prevention of disease and other conditions related to inflammation, neurodegeneration, osteoarthritis and apoptosis are also disclosed.
    Type: Application
    Filed: July 2, 2007
    Publication date: November 22, 2007
    Applicant: Wyeth
    Inventors: Paul Dollings, Arlene Dietrich, Lisa Havran, Chae-Koo Chong, Donna Huryn, Albert Robichaud, Boyd Harrison, Wayne Childers, Alexander Greenfield, James Bicksler, Vasilios Marathias
  • Publication number: 20070135445
    Abstract: Bicyclic indolyl derivatives and compositions containing such compounds are disclosed. Methods of using the bicyclic indolyl derivatives and compositions containing such composition as serotonergic agents, such as in the treatment of depression and anxiety, are also disclosed. In addition, processes for the preparation of bicyclic indolyl derivatives are disclosed.
    Type: Application
    Filed: January 15, 2007
    Publication date: June 14, 2007
    Applicant: Wyeth
    Inventors: Micahel Kelly, Wayne Childers, Boyd Harrison, Gan Zhang, Byron Bravo, Lee Schechter