Patents by Inventor Wayne Cowens

Wayne Cowens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8273537
    Abstract: A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the subject.
    Type: Grant
    Filed: October 25, 2010
    Date of Patent: September 25, 2012
    Assignees: Genomic Health, Inc., NSABP Foundation, Inc.
    Inventors: Drew Watson, Soonmyung Paik, Wayne Cowens, Joffre B. Baker, Kim Clark, James Hackett
  • Publication number: 20120171688
    Abstract: A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the subject.
    Type: Application
    Filed: March 6, 2012
    Publication date: July 5, 2012
    Inventors: Wayne Cowens, Joffre B. Baker, Kim Clark-Langane, James Hackett, Drew Watson, Soonmyung Palk
  • Patent number: 8198024
    Abstract: A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the subject.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: June 12, 2012
    Assignees: Genomic Health, Inc., NSABP Foundation, Inc.
    Inventors: Drew Watson, Soonmyung Paik, Wayne Cowens, Joffre B. Baker, Kim Clark, James Hackett
  • Patent number: 8153378
    Abstract: A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the subject.
    Type: Grant
    Filed: January 29, 2010
    Date of Patent: April 10, 2012
    Assignees: Genomic Health, Inc., NSABP Foundations, Inc.
    Inventors: Wayne Cowens, Joffre B. Baker, Kim Clark, James Hackett, Drew Watson, Soonmyung Paik
  • Patent number: 8153379
    Abstract: A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the subject.
    Type: Grant
    Filed: October 25, 2010
    Date of Patent: April 10, 2012
    Assignees: Genomic Health, Inc., NSABP Foundation, Inc.
    Inventors: Drew Watson, Soonmyung Paik, Wayne Cowens, Joffre B. Baker, Kim Clark, James Hackett
  • Patent number: 8153380
    Abstract: A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the subject.
    Type: Grant
    Filed: October 25, 2010
    Date of Patent: April 10, 2012
    Assignees: Genomic Health, Inc., NSABP Foundation, Inc.
    Inventors: Drew Watson, Soonmyung Paik, Wayne Cowens, Joffre B. Baker, Kim Clark, James Hackett
  • Publication number: 20120040842
    Abstract: The present invention relates to gene sets useful in assessing prognosis and/or predicting the response of cancer, e.g. colorectal cancer to chemotherapy. In addition, the invention relates to a clinically validated cancer test, e.g. colorectal test, for assessment of prognosis and/or prediction of patient response to chemotherapy, using expression analysis. The present invention accommodates the use of archived paraffin embedded biopsy material for assay of all markers in the relevant gene sets and therefore is compatible with the most widely available type of biopsy material.
    Type: Application
    Filed: October 21, 2011
    Publication date: February 16, 2012
    Inventors: Joffre B. Baker, Wayne Cowens, Kim Langone, James Hackett, Drew Watson, Soonmyung Paik
  • Publication number: 20120028264
    Abstract: Molecular assays that involve measurement of expression levels of prognostic biomarkers, or co-expressed biomarkers, from a biological sample obtained from a prostate cancer patient, and analysis of the measured expression levels to provide information concerning the likely prognosis for said patient, and likelihood that said patient will have a recurrence of prostate cancer, or to classify the tumor by likelihood of clinical outcome or TMPRSS2 fusion status, are provided herein.
    Type: Application
    Filed: July 25, 2011
    Publication date: February 2, 2012
    Inventors: Steven Shak, Frederick L. Baehner, Tara Maddala, Mark Lee, Robert J. Pelham, Wayne Cowens, Diana Cherbavaz, Michael C. Kiefer, Michael Crager, Audrey Goddard, Joffre B. Baker
  • Patent number: 8067178
    Abstract: The present invention relates to gene sets useful in assessing prognosis and/or predicting the response of cancer, e.g. colorectal cancer to chemotherapy. In addition, the invention relates to a clinically validated cancer test, e.g. colorectal test, for assessment of prognosis and/or prediction of patient response to chemotherapy, using expression analysis. The present invention accommodates the use of archived paraffin embedded biopsy material for assay of all markers in the relevant gene sets and therefore is compatible with the most widely available type of biopsy material.
    Type: Grant
    Filed: March 13, 2009
    Date of Patent: November 29, 2011
    Assignees: Genomic Health, Inc., NSABP Foundation, Inc.
    Inventors: Joffre B. Baker, Wayne Cowens, Kim Langone, James Hackett, Drew Watson, Soonmyung Paik
  • Patent number: 8029995
    Abstract: A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the subject.
    Type: Grant
    Filed: October 25, 2010
    Date of Patent: October 4, 2011
    Assignees: Genomic Health, Inc., NSABP Foundation, Inc.
    Inventors: Drew Watson, Soonmyung Paik, Wayne Cowens, Joffre B. Baker, Kim Clark, James Hackett
  • Patent number: 8026060
    Abstract: A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the subject.
    Type: Grant
    Filed: October 25, 2010
    Date of Patent: September 27, 2011
    Assignees: Genomic Health, Inc., NSABP Foundation, Inc.
    Inventors: Drew Watson, Soonmyung Paik, Wayne Cowens, Joffre B. Baker, Kim Clark, James Hackett
  • Publication number: 20110171633
    Abstract: The present disclosure provides gene and gene sets, the expression of which is important in the classification and/or prognosis of cancer, in particular of renal cell carcinoma.
    Type: Application
    Filed: January 7, 2011
    Publication date: July 14, 2011
    Inventors: Wayne Cowens, Steven Shak, Audrey Goddard, Dejan Knezevic, Joffre B. Baker, Michael C. Kiefer, Tara Maddala, Frederick L. Baehner
  • Publication number: 20110111421
    Abstract: A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the subject.
    Type: Application
    Filed: January 19, 2011
    Publication date: May 12, 2011
    Inventors: Wayne Cowens, Joffre B. Baker, Kim Clark, James Hackett, Drew Watson, Soonmyung Paik
  • Publication number: 20110097759
    Abstract: A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the subject.
    Type: Application
    Filed: October 25, 2010
    Publication date: April 28, 2011
    Inventors: Wayne Cowens, Joffre B. Baker, Kim Clark, James Hackett, Drew Watson, Soonmyung Paik
  • Publication number: 20110039269
    Abstract: A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the subject.
    Type: Application
    Filed: October 25, 2010
    Publication date: February 17, 2011
    Inventors: Wayne Cowens, Joffre B. Baker, Kim Clark, James Hackett, Drew Watson, Soonmyung Paik
  • Publication number: 20110039270
    Abstract: A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the subject.
    Type: Application
    Filed: October 25, 2010
    Publication date: February 17, 2011
    Inventors: Wayne Cowens, Joffre B. Baker, Kim Clark, James Hackett, Drew Watson, Soonmyung Paik
  • Publication number: 20110039272
    Abstract: A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the subject.
    Type: Application
    Filed: October 25, 2010
    Publication date: February 17, 2011
    Inventors: WAYNE COWENS, JOFFRE B. BAKER, KIM CLARK, JAMES HACKETT, DREW WATSON, SOONMYUNG PAIK
  • Publication number: 20110039271
    Abstract: A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the subject.
    Type: Application
    Filed: October 25, 2010
    Publication date: February 17, 2011
    Inventors: WAYNE COWENS, JOFFRE B. BAKER, KIM CLARK, JAMES HACKETT, DREW WATSON, SOONMYUNG PAIK
  • Publication number: 20100291573
    Abstract: The present disclosure provides methods for assessing a patient's cancer risk and/or recurrence risk, which methods comprise assaying, in a biological sample obtained from the gastrointestinal (GI) tract of the patient, an expression level of a risk gene. The present disclosure also provides methods involving a cancer risk/recurrence risk sequence, i.e. the V600E mutation of the BRAF gene, which is useful for assessing cancer risk and/or recurrence risk in a patient.
    Type: Application
    Filed: April 6, 2010
    Publication date: November 18, 2010
    Inventors: Wayne Cowens, Maureen T. Cronin, Carl L. Millward, Francois Collin, Michael Crager
  • Publication number: 20100190173
    Abstract: A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the subject.
    Type: Application
    Filed: January 29, 2010
    Publication date: July 29, 2010
    Inventors: Wayne Cowens, Joffre B. Baker, Kim Clark, James Hackett, Drew Watson, Soonmyung Paik