Patents by Inventor Wayne D. Luke

Wayne D. Luke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphaplatin liquid formulations
    Patent number: 11154529
    Abstract: Pharmaceutical compositions of phosphaplatin compounds, in particular buffered stable liquid formulations of pyrodach-2 ready for use in the treatment of various cancers, and methods of preparation are disclosed.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: October 26, 2021
    Assignee: Phosplatin Therapeutics Inc.
    Inventors: Wayne D. Luke, Tyler D. Ames
  • Phosphaplatin Liquid Formulations
    Publication number: 20200323810
    Abstract: Pharmaceutical compositions of phosphaplatin compounds, in particular buffered stable liquid formulations of pyrodach-2 ready for use in the treatment of various cancers, and methods of preparation are disclosed.
    Type: Application
    Filed: April 5, 2017
    Publication date: October 15, 2020
    Applicant: Phosplatin Therapeutics LLC
    Inventors: Wayne D. Luke, Tyler Ames
  • Synthetic and purification methods for phosphaplatin compounds and uses thereof
    Patent number: 8859796
    Abstract: This application discloses novel methods and processes for preparation and purification of phosphaplatin compounds. The improvements of the synthetic methods and purification processes include, but are not limited to, efficient and reproducible large-scale preparation of these useful pharmaceutical agents in high quality and good yield.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: October 14, 2014
    Assignee: Phosplatin Therapeutics
    Inventors: Wayne D. Luke, Steffen Jost
  • Synthetic method for phosphaplatin compounds
    Patent number: 8846964
    Abstract: This application discloses novel methods and processes for preparation and purification of phosphaplatin compounds. The improvements of the synthetic methods and purification processes include, but are not limited to, efficient and reproducible large-scale preparation of these useful pharmaceutical agents in high quality and good yield.
    Type: Grant
    Filed: September 20, 2013
    Date of Patent: September 30, 2014
    Assignee: Phosplatin Therapeutics
    Inventors: Wayne D. Luke, Steffen Jost
  • Synthetic and Purification Methods for Phosphaplatin Compounds and Uses Thereof
    Publication number: 20140288321
    Abstract: This application discloses novel methods and processes for preparation and purification of phosphaplatin compounds. The improvements of the synthetic methods and purification processes include, but are not limited to, efficient and reproducible large-scale preparation of these useful pharmaceutical agents in high quality and good yield.
    Type: Application
    Filed: March 18, 2014
    Publication date: September 25, 2014
    Applicant: PHOSPLATIN THERAPEUTICS LLC
    Inventors: Wayne D. Luke, Steffen Jost
  • Synthetic Method for Phosphaplatin Compounds
    Publication number: 20140024848
    Abstract: This application discloses novel methods and processes for preparation and purification of phosphaplatin compounds. The improvements of the synthetic methods and purification processes include, but are not limited to, efficient and reproducible large-scale preparation of these useful pharmaceutical agents in high quality and good yield.
    Type: Application
    Filed: September 20, 2013
    Publication date: January 23, 2014
    Applicant: PHOSPLATIN THERAPEUTICS LLC
    Inventors: Wayne D. Luke, Steffen Jost
  • Process for the synthesis of benzo[b]thiophenes
    Patent number: 5606075
    Abstract: The present invention is directed to new processes for the synthesis of 2-aryl benzo[b]thiophenes.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 25, 1997
    Assignee: Eli Lilly and Company
    Inventors: David W. Hoard, Wayne D. Luke
  • Process for the synthesis of benzo[b]thiophenes
    Patent number: 5569772
    Abstract: The present invention is directed to a new process for the synthesis of 2-aryl benzo[b]thiophenes, and to novel intermediates therefor.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 29, 1996
    Assignee: Eli Lilly and Company
    Inventors: David W. Hoard, Wayne D. Luke
  • Vinyl sulfenic acid derivatives
    Patent number: 5514826
    Abstract: The present invention is directed to novel vinyl sulfenic acid derivatives, useful for the synthesis of benzo b!thiophenes, in particular 2-arylbenzo b!thiophenes.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: May 7, 1996
    Assignee: Eli Lilly and Company
    Inventors: David W. Hoard, Wayne D. Luke
  • Process for the synthesis of vinyl sulfenic acid derivatives
    Patent number: 5512701
    Abstract: The present invention is directed to a new process for the synthesis of vinyl sulfenic acid derivatives. These compounds are useful for the synthesis of benzo b!thiophenes, in particular 2-aryl-benzo b!thiophenes.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 30, 1996
    Assignee: Eli Lilly and Company
    Inventors: David W. Hoard, Wayne D. Luke
  • Process of enantiomeric separation of carbacephem intermediates
    Patent number: 5142038
    Abstract: Enantiomerically pure .beta.-lactam intermediates of the formula (I) ##STR1## are isolated from a haloalkane solvent through precipitation with methyl-t-butyl ether or methanol. The products thus obtained are key intermediates in the synthesis of antibiotic aagents. The process is appropriate for large scale production.
    Type: Grant
    Filed: July 23, 1991
    Date of Patent: August 25, 1992
    Assignee: Eli Lilly and Company
    Inventors: Christopher W. Doecke, Jeffrey N. Levy, Wayne D. Luke, Michael A. Staszak
  • Removal of stannic chloride
    Patent number: 4303591
    Abstract: Stannic chloride is removed from organic solvent-based waste streams by precipitating the salt as a dimethyl sulfoxide complex.
    Type: Grant
    Filed: July 7, 1980
    Date of Patent: December 1, 1981
    Assignee: Eli Lilly and Company
    Inventors: Ta-sen Chou, Perry C. Heath, Wayne D. Luke