Patents by Inventor Wayne Daniel Klohs

Wayne Daniel Klohs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diaminopyrimidines and combination therapies effective for treatment of P-glycoprotein positive cancers
    Publication number: 20040006042
    Abstract: The present invention provides compounds of Formula II: 1
    Type: Application
    Filed: May 28, 2003
    Publication date: January 8, 2004
    Inventors: David Allen Berry, Ellen Myra Dobrusin, Judith Lynne Johnson-Philipsen, Wayne Daniel Klohs, Dennis Joseph McNamara, Leslie Morton Werbel
  • Combination chemotherapy
    Publication number: 20030170300
    Abstract: Acetyldinaline in combination with gemcitabine, a pharmaceutically acceptable salt thereof, capecitabine, or cisplatin is synergistic for treating cancer.
    Type: Application
    Filed: October 8, 2002
    Publication date: September 11, 2003
    Inventors: William Richard Grove, Wayne Daniel Klohs, Ronald Lynn Merriman
  • Combination chemotherapy
    Publication number: 20030134893
    Abstract: Acetyldinaline in combination with paclitaxel and/or carboplatin is synergistic for treating cancer.
    Type: Application
    Filed: February 20, 2003
    Publication date: July 17, 2003
    Inventors: Wayne Daniel Klohs, Ronald Lynn Merriman
  • Combination chemotherapy
    Publication number: 20030086965
    Abstract: Acetyldinaline in combination with gemcitabine, a pharmaceutically acceptable salt thereof, capecitabine, or cisplatin is synergistic for treating cancer.
    Type: Application
    Filed: October 9, 2002
    Publication date: May 8, 2003
    Inventors: William Richard Grove, Wayne Daniel Klohs, Ronald Lynn Merriman
  • Chemotherapy of cancer with actyldinaline in combination with gemcitabine capecitabine or cisplatin
    Patent number: 6469058
    Abstract: Acetyldinaline in combination with gemcitabine, a pharmaceutically acceptable salt thereof, capecitabine, or cisplatin is synergistic for treating cancer.
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: October 22, 2002
    Assignee: Warner-Lambert Company
    Inventors: William Richard Grove, Wayne Daniel Klohs, Ronald Lynn Merriman
  • N-[4-(3-chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide, and irreversible inhibitor of tyrosine kinases
    Patent number: 6344455
    Abstract: This invention relates to the compound N-[4-(3-chloro4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide that is an irreversible inhibitor of tyrosine kinases. This invention also relates to a method of treating cancer, atherosclerosis, restenosis, endometriosis, and psoriasis using the compound N-[4-(3-chloro4-fluoro-phenylamino)-7-(3-morpholin4-yl-propoxy)-quinazolin-6-yl]-acrylamide, and to a pharmaceutical composition that comprises the compound N-[4-(3-chloro4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide.
    Type: Grant
    Filed: May 16, 2001
    Date of Patent: February 5, 2002
    Assignee: Warner-Lambert Company
    Inventors: Alexander James Bridges, Denise Driscoll, Wayne Daniel Klohs
  • Combination chemotherapy
    Patent number: 5767110
    Abstract: Suramin in combination with a vinca alkaloid or estramustine is synergistic for treating cancer.
    Type: Grant
    Filed: December 11, 1996
    Date of Patent: June 16, 1998
    Assignee: Warner-Lambert Company
    Inventors: Wayne Daniel Klohs, Charles Dale Kowal