Patents by Inventor Wayne Everett Childers

Wayne Everett Childers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Serotonergic agents
    Patent number: 7816362
    Abstract: Novel piperazine derivatives are provided having the formula wherein R1 is cyano, nitro, trifluoromethyl or halogen, or pharmaceutically acceptable acid addition salts thereof, which are useful as 5-HT1A receptor antagonists.
    Type: Grant
    Filed: May 5, 2009
    Date of Patent: October 19, 2010
    Assignee: Wyeth LLC
    Inventors: Wayne Everett Childers, Michael Kelly, Sharon Joy Rosenzweig-Lipson
  • Piperazine-piperidine antagonists and agonists of the 5-HT receptor
    Patent number: 7671056
    Abstract: The present invention relates to novel piperazine-piperidine compounds. The compounds are useful as 5-HT1A binding agents, particularly as 5-HT1A receptor antagonists and agonists. These compounds are useful in treating central nervous system disorders, such as cognition disorders, anxiety disorders, depression and sexual dysfunction. The invention relates to compounds and pharmaceutically acceptable salts of formula (I?): wherein R1-R16, Ra, Rb, and n are set forth in the specification. The invention also relates to pharmaceutical compositions comprising compounds and pharmaceutically acceptable salts of formula (I?).
    Type: Grant
    Filed: June 9, 2006
    Date of Patent: March 2, 2010
    Assignee: Wyeth LLC
    Inventors: Magda Asselin, George Theodore Grosu, Annmarie Louise Sabb, Wayne Everett Childers, Lisa Marie Havran, Zhongqi Shen, James Jacob Bicksler, Dan Chaekoo Chong
  • Metabolites of 5-fluoro-8- quinoline and methods of preparation and uses thereof
    Publication number: 20080262228
    Abstract: The present invention relates to novel metabolites of 5-Fluoro-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}quinoline, which can be useful in treating CNS disorders. The present invention further relates to processes for their preparation, to pharmaceutical compositions comprising them, and to methods of using them.
    Type: Application
    Filed: November 27, 2007
    Publication date: October 23, 2008
    Applicant: Wyeth
    Inventors: Jianyao Wang, Alana Upthagrove, Lin Deng, Wayne Everett Childers, Zhongqi Shen, William Demaio, Robin D. Moore, Zeen Tong, Li Shen, Pixu Li, Michael K. May
  • Serotonergic agents for treating sexual dysfunction
    Patent number: 7425558
    Abstract: Methods and compositions are provided for treating sexual dysfunction, e.g., sexual dysfunction associated with drug treatment, using 5-HT1A receptor antagonists.
    Type: Grant
    Filed: August 18, 2006
    Date of Patent: September 16, 2008
    Assignee: Wyeth
    Inventors: Stacey J. Sukoff Rizzo, Sharon Joy Rosenzweig-Lipson, Wayne Everett Childers, Michael Kelly, Lee Erwin Schechter
  • Pyrimidoindolones and methods for using same
    Patent number: 7256198
    Abstract: Novel pyrimidoindolone compounds are disclosed. Methods of using the pyrimidoindolone compounds and compositions containing the compounds in the treatment and/or prevention of disease and other conditions related to inflammation, neurodegeneration, osteoarthritis and apoptosis are also disclosed.
    Type: Grant
    Filed: February 18, 2005
    Date of Patent: August 14, 2007
    Assignee: Wyeth
    Inventors: Paul Jeffrey Dollings, Arlene Joan Dietrich, Lisa Marie Havran, Chae-Koo Dan Chong, Donna Mary Huryn, Albert Jean Robichaud, Boyd Lynn Harrison, Wayne Everett Childers, Alexander A. Greenfield, James Jacob Bicksler, Vasilios Marathias