Patents by Inventor Wayne F. Beyer

Wayne F. Beyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mycobacteriophage specific for the mycobacterium tuberculosis complex
    Patent number: 5582969
    Abstract: Mycobacteriophage DS6A has been characterized and found to specifically infect all species of the TB complex, without any detectable infection of mycobacteria species other than those of the TB complex. DNA sequence analysis revealed several potential open reading frames, including one encoding a protein analogous to gp37 of mycobacteriophage L5 and a second encoding a protein with significant homology to the S. coelicolor DNA polymerase .beta. subunit. Based on the DNA sequence analysis, cloning sites can be identified for insertion of reporter genes, making DS6A useful as a reporter phage for specific detection and identification of species of the TB complex.
    Type: Grant
    Filed: July 27, 1995
    Date of Patent: December 10, 1996
    Assignee: Becton, Dickinson and Company
    Inventors: Robert E. Pearson, Julie A. Dickson, Paul T. Hamilton, Michael C. Little, Wayne F. Beyer, Jr.
  • Mycobacteriophage DSGA specific for the mycobacterium tuberculosis complex
    Patent number: 5476768
    Abstract: Mycobacteriophage DS6A has been characterized and found to specifically infect all species of the TB complex, without any detectable infection of mycobacteria species other than those of the TB complex. DNA sequence analysis revealed several potential open reading frames, including one encoding a protein analogous to gp37 of mycobacteriophage L5 and a second encoding a protein with significant homology to the S. coelicolor DNA polymerase .beta. subunit. Based on the DNA sequence analysis, cloning sites can be identified for insertion of reporter genes, making DS6A useful as a reporter phage for specific detection and identification of species of the TB complex.
    Type: Grant
    Filed: March 10, 1995
    Date of Patent: December 19, 1995
    Assignee: Becton, Dickinson and Company
    Inventors: Robert E. Pearson, Julie A. Dickson, Paul T. Hamilton, Michael C. Little, Wayne F. Beyer, Jr.
  • Superoxide dismutase mimic
    Patent number: 5227405
    Abstract: The invention relates to a water-soluble complex formed between a chelating agent and manganese and pharmaceutical compositions thereof. The complex is a low molecular weight mimic of superoxide dismutase. The invention further relates to a method of using the complex comprising treating plant and animal cells with an amount of the complex sufficient to reduce or prevent superoxide radical-induced toxicity.
    Type: Grant
    Filed: September 28, 1988
    Date of Patent: July 13, 1993
    Assignee: Duke University
    Inventors: Irwin Fridovich, Douglas J. Darr, Wayne F. Beyer