Abstract: A high speed, luminescence detection arrangement for sequentially measuring the luminescence emitted from a plurality of luminescence sources under test. A tray holder contains a plurality of cup-like sample wells, from which the luminescent radiation is emitted, and each of the cup-like sample wells is sequentially positioned in a predetermined location to allow the detection and measurement of the intensity of the luminescence emitted therefrom. Displays are provided to provide a detectible display, having a magnitude proportional to the intensity of the luminescence detected. Fluid dispensing is operatively interconnected to allow injection of one or more fluids into each of the cup-like sample wells at a predetermined time before measurement of the luminescence emitted therefrom.

Abstract: A high speed, luminescence detection arrangement for sequentially measuring the luminescence emitted from a plurality of luminescence sources under test. A tray holder contains a plurality of cup-like sample wells, from which the luminescent radiation is emitted, and each of the cup-like sample wells is sequentially positioned in a predetermined location to allow the detection and measurement of the intensity of the luminescence emitted therefrom. Display means are provided to provide a detectible display, having a magnitude proportional to the intensity of the luminescence detected. Fluid dispensing means are operatively interconnected to allow injection of one or more fluids into each of the cup-like sample wells at a predetermined time before measurement of the luminescence emitted therefrom.

Abstract: A small, disposable cryosurgical probe having a self-contained liquid refrigerant supply can be operated in either a freeze mode or a defrost mode. During the freeze mode the refrigerant is conducted from the supply to the probe tip as a two phase fluid so that the probe can freeze tissue for a relatively long period with a limited refrigerant supply. To facilitate detaching the probe tip from tissue, a button on the probe is depressed which switches the probe to its defrost mode of operation wherein room temperature liquid refrigerant is conducted directly from the supply to the probe tip thereby immediately warming the tip. The probe may be cycled several times between its freeze and defrost modes before the refrigerant supply is exhausted.

Abstract: A small, self-contained, disposable cryosurgical probe has a pencil-like housing with a refrigerant-containing cartridge in the housing and a hollow tip projecting from the housing. A small diameter capillary tube has one end in the housing opposite the cartridge and its other end extending into the tip with the intervening length of the tube formed into a multi-turn coil. The refrigerant is conducted from the cartridge through the tube to the probe tip and the temperature of the refrigerant is stabilized so as to maintain a substantially uniform mass flow rate of refrigerant through the tube to the tip.