Patents by Inventor Wayne Frasch

Wayne Frasch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12378606
    Abstract: The present disclosure relates to nucleic acid probes and kits for determining the length of a region of tandem repeats in a subject's genome and methods of using the DNA probes for determining the length of a region of tandem repeats in a subject's genome. In some embodiments, the region of tandem repeats in telomeres.
    Type: Grant
    Filed: October 11, 2021
    Date of Patent: August 5, 2025
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventors: Wayne Frasch, Fusheng Xiong
  • Publication number: 20220195521
    Abstract: The present disclosure relates to nucleic acid probes and kits for determining the length of a region of tandem repeats in a subject's genome and methods of using the DNA probes for determining the length of a region of tandem repeats in a subject's genome. In some embodiments, the region of tandem repeats in telomeres.
    Type: Application
    Filed: October 11, 2021
    Publication date: June 23, 2022
    Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Wayne Frasch, Fusheng Xiong
  • Patent number: 11168366
    Abstract: The present disclosure relates to kits for determining the length of a region of tandem repeats in a subject's genome. In some embodiments, the region of tandem repeats in telomeres.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: November 9, 2021
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Wayne Frasch, Fusheng Xiong
  • Publication number: 20200291475
    Abstract: The present disclosure relates to kits for determining the length of a region of tandem repeats in a subject's genome. In some embodiments, the region of tandem repeats in telomeres.
    Type: Application
    Filed: May 28, 2020
    Publication date: September 17, 2020
    Inventors: Wayne Frasch, Fusheng Xiong
  • Patent number: 10718017
    Abstract: The present disclosure relates to nucleic acid probes and kits for determining the length of a region of tandem repeats in a subject's genome and methods of using the DNA probes for determining the length of a region of tandem repeats in a subject's genome. In some embodiments, the region of tandem repeats in telomeres.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: July 21, 2020
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Wayne Frasch, Fusheng Xiong
  • Publication number: 20190338355
    Abstract: The present disclosure relates to nucleic acid probes and kits for determining the length of a region of tandem repeats in a subject's genome and methods of using the DNA probes for determining the length of a region of tandem repeats in a subject's genome. In some embodiments, the region of tandem repeats in telomeres.
    Type: Application
    Filed: March 31, 2017
    Publication date: November 7, 2019
    Inventors: Wayne Frasch, Fusheng Xiong
  • Publication number: 20120196771
    Abstract: Methods, compositions, and kits for nucleic acid detection.
    Type: Application
    Filed: November 17, 2011
    Publication date: August 2, 2012
    Applicant: ARIZONA BOARD OF REGENTS, A BODY CORPORATE ACTING FOR & ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Wayne Frasch, David Spetzler, Justin York
  • Patent number: 8126649
    Abstract: The present invention provides methods for generating a distribution of optimal answers to a nondeterministic polynomial optimization problem by providing a plurality of solutions comprising input polynucleotides, wherein each solution comprises identical input polynucleotides; and wherein the number of solutions comprising polynucleotides equals a number of data inputs in the problem to be answered, and wherein each input polynucleotide comprises an x segment and a y segment; providing a plurality of solutions comprising connection polynucleotides wherein each solution comprises identical connection polynucleotides; and wherein the number of solutions comprising connection polynucleotides equals a number of unique connections that can be made between the different data inputs, and wherein each polynucleotide in the set of connection polynucleotides is complementary to the x segment of one input polynucleotide and to the y segment of one different input polynucleotide; combining the solutions comprising the i
    Type: Grant
    Filed: July 28, 2008
    Date of Patent: February 28, 2012
    Assignee: Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Arizona State University
    Inventors: Wayne Frasch, David Spetzler, Justin York, Fusheng Xiong
  • Patent number: 8084206
    Abstract: The present invention provides methods, compositions, and kits for nucleic acid detection.
    Type: Grant
    Filed: August 29, 2007
    Date of Patent: December 27, 2011
    Assignee: Arizona Board of Regents, a body corporate acting for and on behalf of Arizona State University
    Inventors: Wayne Frasch, David Spetzler, Justin York
  • Patent number: 8076079
    Abstract: The present invention provides methods and compositions for highly sensitive nucleic acid detection, down to the single nucleic acid molecule level.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: December 13, 2011
    Assignee: Arizona Board of Regents, a body coporate acting for and on behalf of Arizona State University
    Inventors: Wayne Frasch, Lyian He
  • Publication number: 20100015616
    Abstract: The present invention provides methods, compositions, and kits for nucleic acid detection.
    Type: Application
    Filed: August 29, 2007
    Publication date: January 21, 2010
    Applicant: Arizona Board of Regets, a body corporate acting for and on behalf of Arizona State University
    Inventors: Wayne Frasch, David Spetzler, Justin York
  • Publication number: 20090047677
    Abstract: The present invention overcomes problems in prior art DNA-based computing methods for solving non-deterministic polynomial optimization problems, by providing methods that derive the most probable answers in a statistically significant manner that makes the methods scalable with increases in the number of data inputs, and thus makes the methods practical.
    Type: Application
    Filed: July 28, 2008
    Publication date: February 19, 2009
    Applicants: Arizona State University
    Inventors: Wayne Frasch, David Spetzler, Justin York, Fusheng Xiong
  • Publication number: 20090035751
    Abstract: The present invention provides methods and compositions for highly sensitive nucleic acid detection, down to the single nucleic acid molecule level.
    Type: Application
    Filed: December 17, 2004
    Publication date: February 5, 2009
    Applicant: ARIZONA BOARD OF REGENTS, a body corporate acting on behalf of ARIZONA STATE UNIVERSITY
    Inventors: Lyian He, Wayne Frasch
  • Publication number: 20060110738
    Abstract: A nanoscale motion detector attaches a gold nanorod (30) to the rotating arm (26) of a molecular structure (10) to cause the nanoparticle to rotate. The molecular structure is an F1-ATPase enzyme. The gold nanorod is exposed to a light source. The long axis of the gold nanorod scatters red light when the nanorod is in a first position. The short axis of the gold nanorod scatters green light when the nanorod is in a second position. A polarizing filter filters the red and green light to detect the rotational motion by observing alternating red and green lights. A detection DNA stand (50) is coupled between the gold nanorod and the molecular structure. The detection DNA strand hybridizes with a target DNA strand (58) if the target DNA strand matches the detection DNA strand to form a structural link between the molecular structure and gold nanorod.
    Type: Application
    Filed: December 11, 2003
    Publication date: May 25, 2006
    Inventors: Wayne Frasch, Lars Chapsky