Patents by Inventor Wayne Hogrefe

Wayne Hogrefe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for detecting herpes simplex virus type 2
    Patent number: 8846391
    Abstract: The invention provides methods for sensitive and specific detection of anti-HSV-2 antibodies by depletion of cross-reactive (non-specific) antibodies in a biological sample that can lead to a false positive result. The invention also features compositions, including nucleic acids, polypeptides, and kits, for use in the methods of the invention.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: September 30, 2014
    Assignee: Focus Diagnostics, Inc.
    Inventors: Xin Su, Lilly Kong, Wayne Hogrefe
  • METHODS AND COMPOSITIONS FOR DETECTING HERPES SIMPLEX VIRUS TYPE 2
    Publication number: 20110059553
    Abstract: The invention provides methods for sensitive and specific detection of anti-HSV-2 antibodies by depletion of cross-reactive (non-specific) antibodies in a biological sample that can lead to a false positive result. The invention also features compositions, including nucleic acids, polypeptides, and kits, for use in the methods of the invention.
    Type: Application
    Filed: June 23, 2010
    Publication date: March 10, 2011
    Inventors: Xin Su, Lilly Kong, Wayne Hogrefe
  • Methods and compositions for detecting herpes simplex virus type 2
    Patent number: 7763460
    Abstract: The invention provides methods for sensitive and specific detection of anti-HSV-2 antibodies by depletion of cross-reactive (non-specific) antibodies in a biological sample that can lead to a false positive result. The invention also features compositions, including nucleic acids, polypeptides, and kits, for use in the methods of the invention.
    Type: Grant
    Filed: December 6, 2005
    Date of Patent: July 27, 2010
    Assignee: Focus Diagnostics, Inc.
    Inventors: Xin Su, Lilly Kong, Wayne Hogrefe
  • Oxidized fungal antigens and methods of making and using thereof
    Patent number: 7205114
    Abstract: The present invention relates to oxidized fungal antigens and methods of making and using thereof. More particularly, the present invention provides a method for producing an oxidized fungal antigen in culture filtrate. The present invention also provides for the produced oxidized fungal antigens. Devices comprising such oxidized fungal antigens, methods for testing for fungal antibodies using the oxidized fungal antigens and methods for producing anti-fungal antibodies using oxidized fungal antigens are further provided. Antigen detection devices comprising anti-fungal antibodies raised against oxidized fungal antigens produced by the present methods are further provided.
    Type: Grant
    Filed: May 13, 2004
    Date of Patent: April 17, 2007
    Assignee: Focus Technologies, Inc.
    Inventors: Harry Prince, Xin Su, Lilly Kong, Celine Ngo, legal representative, Sergei Arakelov, Wayne Hogrefe, Ken Devor, deceased
  • Methods and compositions for detecting herpes simplex virus type 2
    Publication number: 20060292557
    Abstract: The invention provides methods for sensitive and specific detection of anti-HSV-2 antibodies by depletion of cross-reactive (non-specific) antibodies in a biological sample that can lead to a false positive result. The invention also features compositions, including nucleic acids, polypeptides, and kits, for use in the methods of the invention.
    Type: Application
    Filed: December 6, 2005
    Publication date: December 28, 2006
    Inventors: Xin Su, Lilly Kong, Wayne Hogrefe
  • Oxidized fungal antigens and methods of making and using thereof
    Publication number: 20050112708
    Abstract: The present invention relates to oxidized fungal antigens and methods of making and using thereof. More particularly, the present invention provides a method for producing an oxidized fungal antigen in culture filtrate. The present invention also provides for the produced oxidized fungal antigens. Devices comprising such oxidized fungal antigens, methods for testing for fungal antibodies using the oxidized fungal antigens and methods for producing anti-fungal antibodies using oxidized fungal antigens are further provided. Antigen detection devices comprising anti-fungal antibodies raised against oxidized fungal antigens produced by the present methods are further provided.
    Type: Application
    Filed: May 13, 2004
    Publication date: May 26, 2005
    Inventors: Harry Prince, Xin Su, Lilly Kong, Ken Devor, Sergei Arakelov, Wayne Hogrefe, Celine Ngo
  • Methods of using oxidized fungal antigens in antibody testing
    Patent number: 6867004
    Abstract: The present invention relates to oxidized fungal antigens and methods of making and using thereof. More particularly, the present invention provides a method for producing an oxidized fungal antigen in culture filtrate. The present invention also provides for the produced oxidized fungal antigens. Devices comprising such oxidized fungal antigens, methods for testing for fungal antibodies using the oxidized fungal antigens and methods for producing anti-fungal antibodies using oxidized fungal antigens are further provided. Antigen detection devices comprising anti-fungal antibodies raised against oxidized fungal antigens produced by the present methods are further provided.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: March 15, 2005
    Assignee: Focus Technologies, Inc.
    Inventors: Harry Prince, Xin Su, Lilly Kong, Ken Devor, Sergei Arakelov, Wayne Hogrefe
  • Oxidized fungal antigens and methods of making and using thereof
    Publication number: 20030124630
    Abstract: The present invention relates to oxidized fungal antigens and methods of making and using thereof. More particularly, the present invention provides a method for producing an oxidized fungal antigen in culture filtrate. The present invention also provides for the produced oxidized fungal antigens. Devices comprising such oxidized fungal antigens, methods for testing for fungal antibodies using the oxidized fungal antigens and methods for producing anti-fungal antibodies using oxidized fungal antigens are further provided. Antigen detection devices comprising anti-fungal antibodies raised against oxidized fungal antigens produced by the present methods are further provided.
    Type: Application
    Filed: December 21, 2001
    Publication date: July 3, 2003
    Inventors: Harry Prince, Xin Su, Lilly Kong, Ken Devor, Sergei Arakelov, Wayne Hogrefe