Abstract: Therapeutics and methods of treating COVID-19 comprising in a patient comprising administering to the patient an effective dose of a pharmacologic composition containing a first therapeutic; wherein the first therapeutic is a hydrogen sulfide (H2S) donor, or a salt, solvate, ester, amide, clathrate, stereoisomer, enantiomer, prodrug or analogs thereof. According to a further embodiment the H2S donor is one of include diallyl trisulfide (DATS), diallyl disulfide (DADS), sodium sulfide, acillin, sugammadex, sulfanilamide, disulfram, sulfonamide, a sulfinate, a sulfoxide, a persulfide, a polysulfide, and a sulfone. According to a further embodiment the pharmacologic composition further contains a second therapeutic, wherein the second therapeutic is a nitrite, or a salt, solvate, ester, amide, clathrate, stereoisomer, enantiomer, prodrug or analogs thereof. According to a further embodiment wherein the nitrite is an inorganic nitrite.

Abstract: Therapeutics and methods for treating a stroke in a human comprising administering a therapeutic to the patient, wherein the therapeutic comprises one of immortalized human placenta mesenchymal stem cells (hPMSCs) and a product from the immortalized hPMSCs. Methods and therapeutic products comprising extracellular vesicles (EVs) isolated from of immortalized hPMSCs. Therapeutics and methods of treating COVID-19 disease vascular injury comprising administering a therapeutic to the patient, wherein the therapeutic comprises one of hPMSCs and a product from the hPMSCs.

Abstract: Therapeutics and methods of treating one of an angiotensin-converting enzyme 2 (ACE2) associated condition and an ACE2 associated pre-condition patient comprising administering to the patient a pharmaceutically therapeutic dose of a therapeutic, wherein the therapeutic includes either a Sigmar1 antagonist or any pharmaceutically acceptable salt, solvate, or prodrug thereof, or a Sigmar1 enhancer, or any pharmaceutically acceptable salt, solvate, or prodrug thereof. A method of treating coronavirus disease 2019 (COVID-19) patient comprising administering to the patient a pharmaceutically therapeutic dose of a therapeutic, wherein the therapeutic includes a Sigmar1 enhancer, or any pharmaceutically acceptable salt, solvate, or prodrug thereof.

Abstract: A method of treating a condition in a mammal comprising: administering a pharmacologically effective amount of a therapeutic; wherein the therapeutic one of decreases EphA2 expression and inhibits ephrin type-A receptor 2; and the condition is a proinflammatory or fibroproliferative condition.

Abstract: A method of treating a condition in a mammal comprising administering a pharmacologically effective amount of a therapeutic, wherein the therapeutic one of increases EphA2 expression and supplements ephrin type-A receptor 2, and the condition is one of fatty liver disease, elevated plasma cholesterol level, and elevated plasma triglyceride level.

Abstract: A container for nestably holding a sink for storing, shipping and displaying. The container forms from a blank of corrugated paperboard scored for folding to provide a back, two opposing side walls, and two opposing end walls. The back includes an opening for partially receiving therethrough the bowl of the sink. A pair of supports are each foldably attached along a first score to a respective one of the end walls. A plurality of sections in the support are defined by second scores. The support folds on the scores and bears against the bottom and the end wall. The sink sits on the support. Two containers are nested together by placing one container on the other. This positions the bottom side of the bowl of one sink in the bowl of the second sink.

Abstract: A container for nestably holding a sink for storing, shipping and displaying. The container forms from a blank of corrugated paperboard scored for folding to provide a back, two opposing side walls, and two opposing end walls. The back includes an opening for partially receiving therethrough the bowl of the sink. A pair of supports are each foldably attached along a first score to a respective one of the end walls. A plurality of sections in the support are defined by second scores. The support folds on the scores and bears against the bottom and the end wall. The sink sits on the support. Two containers are nested together by placing one container on the other. This positions the bottom side of the bowl of one sink in the bowl of the second sink.