Patents by Inventor Wayne R. Gombotz

Wayne R. Gombotz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS FOR INHIBITING MASP-2 DEPENDENT COMPLEMENT ACTIVATION
    Publication number: 20240092938
    Abstract: The present invention relates to anti-MASP-2 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-2 dependent complement activation.
    Type: Application
    Filed: February 13, 2023
    Publication date: March 21, 2024
    Inventors: Thomas Dudler, Wayne R. Gombotz, James Brian Parent, Clark E. Tedford, Anita Kavlie, Urs Beat Hagemann, Herald Reiersen, Sergej Kiprijanov
  • Compositions for inhibiting MASP-2 dependent complement activation
    Patent number: 11613589
    Abstract: The present invention relates to anti-MASP-2 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-2 dependent complement activation.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: March 28, 2023
    Assignee: OMEROS CORPORATION
    Inventors: Thomas Dudler, Wayne R. Gombotz, James Brian Parent, Clark E. Tedford, Anita Kavlie, Urs Beat Hagemann, Herald Reiersen, Sergej Kiprijanov
  • COMPOSITIONS FOR INHIBITING MASP-2 DEPENDENT COMPLEMENT ACTIVATION
    Publication number: 20210054099
    Abstract: The present invention relates to anti-MASP-2 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-2 dependent complement activation.
    Type: Application
    Filed: April 24, 2020
    Publication date: February 25, 2021
    Inventors: Thomas Dudler, Wayne R. Gombotz, James Brian Parent, Clark E. Tedford, Anita Kavlie, Urs Beat Hagemann, Herald Reiersen, Sergej Kiprijanov
  • Compositions for inhibiting MASP-2 dependent complement activation
    Patent number: 10683367
    Abstract: The present invention relates to anti-MASP-2 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-2 dependent complement activation.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: June 16, 2020
    Assignee: Omeros Corporation
    Inventors: Thomas Dudler, Wayne R. Gombotz, James Brian Parent, Clark E. Tedford, Anita Kavlie, Urs Beat Hagemann, Herald Reiersen, Sergej Kiprijanov
  • Compositions for Inhibiting MASP-2 Dependent Complement Activation
    Publication number: 20190119402
    Abstract: The present invention relates to anti-MASP-2 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-2 dependent complement activation.
    Type: Application
    Filed: July 13, 2018
    Publication date: April 25, 2019
    Inventors: Thomas Dudler, Wayne R. Gombotz, James Brian Parent, Clark E. Tedford, Anita Kavlie, Urs Beat Hagemann, Herald Reiersen, Sergej Kiprijanov
  • Stable Anti-inflammatory Solutions for Injection
    Publication number: 20180344855
    Abstract: The present invention relates to stable liquid formulations of ketoprofen, amitriptyline, and oxymetazoline.
    Type: Application
    Filed: January 31, 2018
    Publication date: December 6, 2018
    Inventors: Gregory A. Demopulos, Wayne R. Gombotz, Hui-rong Shen
  • Compositions for inhibiting MASP-2 dependent complement activation
    Patent number: 10047165
    Abstract: The present invention relates to anti-MASP-2 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-2 dependent complement activation.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: August 14, 2018
    Assignee: Omeros Corporation
    Inventors: Thomas Dudler, Wayne R. Gombotz, James Brian Parent, Clark E. Tedford, Anita Kavlie, Urs Beat Hagemann, Herald Reiersen, Sergej Kiprijanov
  • Cyclooxygenase inhibitor and calcium channel antagonist compositions and methods for use in urological procedures
    Patent number: 9855256
    Abstract: Compositions of a cyclooxygenase inhibitor and a calcium channel antagonist in a liquid carrier. The composition may be administered the urinary tract during urological diagnostic, interventional, surgical and other medical procedures. One disclosed composition comprises ketoprofen and nifedipine in a liquid irrigation carrier, and includes a solubilizing agent, stabilizing agents and a buffering agent.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: January 2, 2018
    Assignee: Omeros Corporation
    Inventors: Gregory A. Demopulos, Jeffrey M. Herz, Wayne R. Gombotz, Hui-rong Shen
  • Mixed micelles
    Patent number: 9655981
    Abstract: This disclosure is directed to mixed micelle compositions for administration of e.g., therapeutic agents or imaging agents to a subject.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: May 23, 2017
    Assignees: Omeros Corporation, University of Washington through it's center For Commercialization
    Inventors: Wayne R. Gombotz, Suzie Pun, Christopher Mount, Tae Hee Kim, Benjamin W. Dulken
  • COMPOSITIONS FOR INHIBITING MASP-2 DEPENDENT COMPLEMENT ACTIVATION
    Publication number: 20170088632
    Abstract: The present invention relates to anti-MASP-2 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-2 dependent complement activation.
    Type: Application
    Filed: September 13, 2016
    Publication date: March 30, 2017
    Inventors: Thomas Dudler, Wayne R. Gombotz, James Brian Parent, Clark E. Tedford, Anita Kavlie, Urs Beat Hagemann, Herald Reiersen, Sergej Kiprijanov
  • Cyclooxygenase Inhibitor and Calcium Channel Antagonist Compositions and Methods for Use in Urological Procedures
    Publication number: 20160317515
    Abstract: Compositions of a cyclooxygenase inhibitor and a calcium channel antagonist in a liquid carrier. The composition may be administered the urinary tract during urological diagnostic, interventional, surgical and other medical procedures. One disclosed composition comprises ketoprofen and nifedipine in a liquid irrigation carrier, and includes a solubilizing agent, stabilizing agents and a buffering agent.
    Type: Application
    Filed: May 3, 2016
    Publication date: November 3, 2016
    Inventors: Gregory A. Demopulos, Jeffrey M. Herz, Wayne R. Gombotz, Hui-rong Shen
  • Compositions for inhibiting MASP-2 dependent complement activation
    Patent number: 9475885
    Abstract: The present invention relates to anti-MASP-2 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-2 dependent complement activation.
    Type: Grant
    Filed: March 17, 2015
    Date of Patent: October 25, 2016
    Assignee: Omeros Corporation
    Inventors: Thomas Dudler, Wayne R. Gombotz, James Brian Parent, Clark E. Tedford, Anita Kavlie, Urs Beat Hagemann, Herald Reiersen, Sergej Kiprijanov
  • MIXED MICELLES
    Publication number: 20160228580
    Abstract: This disclosure is directed to mixed micelle compositions for administration of e.g., therapeutic agents or imaging agents to a subject.
    Type: Application
    Filed: February 19, 2016
    Publication date: August 11, 2016
    Inventors: Wayne R. Gombotz, Suzie Pun, Christopher Mount, Tae Hee Kim, Benjamin W. Dulken
  • Stable Anti-inflammatory Solutions for Injection
    Publication number: 20160166696
    Abstract: The present invention relates to stable liquid formulations of ketoprofen, amitriptyline, and oxymetazoline.
    Type: Application
    Filed: December 16, 2015
    Publication date: June 16, 2016
    Inventors: Gregory A. Demopulos, Wayne R. Gombotz, Hui-rong Shen
  • Mixed micelles
    Patent number: 9295685
    Abstract: This disclosure is directed to mixed micelle compositions for administration of e.g., therapeutic agents or imaging agents to a subject.
    Type: Grant
    Filed: February 23, 2012
    Date of Patent: March 29, 2016
    Assignees: Omeros Corporation, University of Washington through it's center For Commercialization
    Inventors: Wayne R. Gombotz, Suzie Pun, Christopher Mount, Tae Hee Kim, Benjamin W. Dulken
  • COMPOSITIONS FOR INHIBITING MASP-2 DEPENDENT COMPLEMENT ACTIVATION
    Publication number: 20160002349
    Abstract: The present invention relates to anti-MASP-2 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-2 dependent complement activation.
    Type: Application
    Filed: March 17, 2015
    Publication date: January 7, 2016
    Inventors: Thomas Dudler, Wayne R. Gombotz, James Brian Parent, Clark E. Tedford, Anita Kavlie, Urs Beat Hagemann, Herald Reiersen, Sergej Kiprijanov
  • Compositions for inhibiting MASP-2 dependent complement activation
    Patent number: 9011860
    Abstract: The present invention relates to anti-MASP-2 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-2 dependent complement activation.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: April 21, 2015
    Assignee: Omeros Corporation
    Inventors: Thomas Dudler, Wayne R. Gombotz, James Brian Parent, Clark E. Tedford, Anita Kavlie, Urs Beat Hagemann, Herald Reiersen, Sergej Kiprijanov
  • Cyclooxygenase Inhibitor and Calcium Channel Antagonist Compositions and Methods for Use in Urological Procedures
    Publication number: 20150031728
    Abstract: Compositions of a cyclooxygenase inhibitor and a calcium channel antagonist in a liquid carrier. The composition may be administered the urinary tract during urological diagnostic, interventional, surgical and other medical procedures. One disclosed composition comprises ketoprofen and nifedipine in a liquid irrigation carrier, and includes a solubilizing agent, stabilizing agents and a buffering agent.
    Type: Application
    Filed: June 26, 2014
    Publication date: January 29, 2015
    Inventors: Gregory A. Demopulos, Jeffrey M. Herz, Wayne R. Gombotz, Hui-rong Shen
  • Cyclooxygenase inhibitor and calcium channel antagonist compositions and methods for use in urological procedures
    Patent number: 8790696
    Abstract: Compositions of a cyclooxygenase inhibitor and a calcium channel antagonist in a liquid carrier. The composition may be administered the the urinary tract during urological diagnostic, interventional, surgical and other medical procedures. One disclosed composition comprises ketoprofen and nifedipine in a liquid irrigation carrier, and includes a solubilizing agent, stabilizing agents and a buffering agent.
    Type: Grant
    Filed: March 17, 2006
    Date of Patent: July 29, 2014
    Assignee: Omeros Corporation
    Inventors: Gregory A. Demopulos, Jeffrey M. Herz, Wayne R. Gombotz, Hui-Rong Shen
  • Stable Anti-inflammatory Solutions for Injection
    Publication number: 20130035362
    Abstract: The present invention relates to stable liquid formulations of ketoprofen, amitriptyline, and oxymetazoline.
    Type: Application
    Filed: August 3, 2012
    Publication date: February 7, 2013
    Applicant: OMEROS CORPORATION
    Inventors: Gregory A. Demopulos, Wayne R. Gombotz, Hui-rong Shen