Patents by Inventor Wayne R. Matson

Wayne R. Matson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection and modification of gut microbial population
    Patent number: 11287417
    Abstract: Methods and systems for evaluating heath/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.
    Type: Grant
    Filed: June 9, 2021
    Date of Patent: March 29, 2022
    Assignee: IXCELA, INC.
    Inventors: Wayne R. Matson, Samantha A. Matson, Erika N. Ebbel-Angle, Srikant Sarangi
  • Detection and modification of gut microbial population
    Patent number: 11287419
    Abstract: Methods and systems for evaluating health/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.
    Type: Grant
    Filed: June 9, 2021
    Date of Patent: March 29, 2022
    Assignee: IXCELA, INC.
    Inventors: Wayne R. Matson, Samantha A. Matson, Erika N. Ebbel-Angle, Srikant Sarangi
  • Detection and modification of gut microbial population
    Patent number: 11287420
    Abstract: Methods and systems for evaluating heath/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.
    Type: Grant
    Filed: June 9, 2021
    Date of Patent: March 29, 2022
    Assignee: IXCELA, INC.
    Inventors: Wayne R. Matson, Samantha A. Matson, Erika N. Ebbel-Angle, Srikant Sarangi
  • Detection and modification of gut microbial population
    Patent number: 11287418
    Abstract: Methods and systems for evaluating health/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's health based on the metabolite levels measured.
    Type: Grant
    Filed: June 9, 2021
    Date of Patent: March 29, 2022
    Assignee: IXCELA, INC.
    Inventors: Wayne R. Matson, Samantha A. Matson, Erika N. Ebbel-Angle, Srikant Sarangi
  • DETECTION AND MODIFICATION OF GUT MICROBIAL POPULATION
    Publication number: 20210405028
    Abstract: Methods and systems for evaluating heath/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.
    Type: Application
    Filed: June 9, 2021
    Publication date: December 30, 2021
    Inventors: Wayne R. MATSON, Samantha A. MATSON, Erika N. EBBEL-ANGLE, Srikant SARANGI
  • DETECTION AND MODIFICATION OF GUT MICROBIAL POPULATION
    Publication number: 20210372991
    Abstract: Methods and systems for evaluating heath/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.
    Type: Application
    Filed: June 9, 2021
    Publication date: December 2, 2021
    Inventors: Wayne R. MATSON, Samantha A. MATSON, Erika N. EBBEL-ANGLE, Srikant SARANGI
  • DETECTION AND MODIFICATION OF GUT MICROBIAL POPULATION
    Publication number: 20210302415
    Abstract: Methods and systems for evaluating heath/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.
    Type: Application
    Filed: June 9, 2021
    Publication date: September 30, 2021
    Inventors: Wayne R. MATSON, Samantha A. MATSON, Erika N. EBBEL-ANGLE, Srikant SARANGI
  • DETECTION AND MODIFICATION OF GUT MICROBIAL POPULATION
    Publication number: 20210302414
    Abstract: Methods and systems for evaluating health/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's health based on the metabolite levels measured.
    Type: Application
    Filed: June 9, 2021
    Publication date: September 30, 2021
    Inventors: Wayne R. MATSON, Samantha A. MATSON, Erika N. EBBEL-ANGLE, Srikant SARANGI
  • Modulating the aryl hydrocarbon receptor system to treat major depressive disorder
    Patent number: 11122997
    Abstract: Materials and methods for treating major depressive disorder by modulating the aryl hydrocarbon receptor system are provided herein.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: September 21, 2021
    Assignees: Mayo Foundation for Medical Education and Research, Ixcela Inc., Duke University
    Inventors: Balmiki Ray, Liewei Wang, Joanna Biernacka, Mark Frye, Richard M. Weinshilboum, Michiaki Kubo, Taisei Mushiroda, Wayne R. Matson, Rima Kaddurah-Daouk
  • Detection and modification of gut microbial population
    Patent number: 11041847
    Abstract: Methods and systems for evaluating heath/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.
    Type: Grant
    Filed: April 27, 2020
    Date of Patent: June 22, 2021
    Assignee: IXCELA, INC.
    Inventors: Wayne R. Matson, Samantha A. Matson, Erika N. Ebbel-Angle, Srikant Sarangi
  • IPA as a protective agent
    Patent number: 10278958
    Abstract: Provided is a method for reducing a potential for neurological damage of an animal at risk of head injury, by administering to the animal before exposure to the risk indole-3-propionic acid, indole lactic acid, or a salt, ester or protein complex or marginally bound preparation thereof, or a mixture thereof, in a suitable carrier.
    Type: Grant
    Filed: October 3, 2017
    Date of Patent: May 7, 2019
    Assignee: IXCELA, INC.
    Inventor: Wayne R. Matson
  • MODULATING THE ARYL HYDROCARBON RECEPTOR SYSTEM TO TREAT MAJOR DEPRESSIVE DISORDER
    Publication number: 20180098722
    Abstract: Materials and methods for treating major depressive disorder by modulating the aryl hydrocarbon receptor system are provided herein.
    Type: Application
    Filed: April 15, 2016
    Publication date: April 12, 2018
    Applicants: Mayo Foundation for Medical Education and Research, Ixcela Inc., Duke University
    Inventors: Balmiki Ray, Liewei Wang, Joanna Biernacka, Mark Frye, Richard M. Weinshilboum, Michiaki Kubo, Taisei Mushiroda, Wayne R. Matson, Rima Kaddurah-Daouk
  • IPA AS A PROTECTIVE AGENT
    Publication number: 20180042897
    Abstract: Provided is a method for reducing a potential for neurological damage of an animal at risk of head injury, by administering to the animal before exposure to the risk indole-3-propionic acid, indole lactic acid, or a salt, ester or protein complex or marginally bound preparation thereof, or a mixture thereof, in a suitable carrier.
    Type: Application
    Filed: October 3, 2017
    Publication date: February 15, 2018
    Inventor: Wayne R. Matson
  • Indole lactic acid or a mixture of indole lactic acid and indole-3-propionic acid for treatment of Huntington's disease
    Patent number: 9636325
    Abstract: Indole-3-propionic acid as a marker and for treatment for Huntington Disease.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: May 2, 2017
    Assignee: IXCELA, INC.
    Inventor: Wayne R. Matson
  • IPA as a therapeutic agent and a biomarker for disease risk for Huntington's disease
    Patent number: 9603837
    Abstract: Indole-3-propionic acid as a marker and for treatment for Huntington Disease.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: March 28, 2017
    Assignee: IXCELA, INC.
    Inventor: Wayne R. Matson
  • SYSTEMS BIOLOGY APPROACH TO THERAPY
    Publication number: 20150363547
    Abstract: A method comprising analyzing multiple component data between or among categories of individuals to develop therapeutic lead compounds through analysis of biochemical networks linking the genome, transcriptome, proteome, metabolome, gut microbiome and environmental factors.
    Type: Application
    Filed: August 17, 2015
    Publication date: December 17, 2015
    Inventor: Wayne R. Matson
  • SYSTEMS BIOLOGY APPROACH TO THERAPY
    Publication number: 20150363548
    Abstract: A method comprising analyzing multiple component data between or among categories of individuals to develop therapeutic lead compounds through analysis of biochemical networks linking the genome, transcriptome, proteome, metabolome, gut microbiome and environmental factors.
    Type: Application
    Filed: August 17, 2015
    Publication date: December 17, 2015
    Inventor: Wayne R. Matson
  • IPA AS A THERAPEUTIC AGENT, AS A PROTECTIVE AGENT, AND AS A BIOMARKER OF DISEASE RISK
    Publication number: 20150216845
    Abstract: Indole-3-propionic acid as a marker and for treatment for Huntington Disease.
    Type: Application
    Filed: April 16, 2015
    Publication date: August 6, 2015
    Inventor: Wayne R. Matson
  • IPA AS A THERAPEUTIC AGENT, AS A PROTECTIVE AGENT, AND AS A BIOMARKER OF DISEASE RISK
    Publication number: 20150111942
    Abstract: Indole-3-propionic acid as a marker and for treatment for Huntington Disease.
    Type: Application
    Filed: October 15, 2014
    Publication date: April 23, 2015
    Inventor: Wayne R. Matson
  • SYSTEMS BIOLOGY APPROACH TO THERAPY
    Publication number: 20150019189
    Abstract: A method comprising analyzing multiple component data between or among categories of individuals to develop therapeutic lead compounds through analysis of biochemical networks linking the genome, transcriptome, proteome, metabolome, gut microbiome and environmental factors.
    Type: Application
    Filed: July 1, 2014
    Publication date: January 15, 2015
    Inventor: Wayne R. Matson