Abstract: A method may comprise receiving, at a central controller, a command, from a remote control, to adjust a feature of a first component of an air mattress framework; relaying, from the central controller, the command to the first component; receiving from the first component at the central controller, an indication of the success of the command; and relaying the indication from the central controller to the remote control.

Abstract: Systems and methods are described for transmitting information optically. For instance, a system may include an optical source configured to generate a beam of light. The system may include at least one modulator configured to encode data on the beam of light to produce an encoded beam of light/encoded plurality of pulses. The system may include a spectrally-equalizing amplifier configured to receive the encoded beam of light/encoded plurality of pulses from the at least one modulator and both amplify and filter the encoded beam of light/encoded plurality of pulses to produce a filtered beam of light/filtered plurality of pulses, thereby spectrally equalizing a gain applied to the encoded beam of light. In some cases, the system may slice the beam of slight, to ensure a detector has impulsive detection. In some cases, the system may include a temperature controller to shift a distribution curve of wavelengths of the optical source.

Abstract: A vascular prosthesis deployment device and related methods are disclosed. In some embodiments the deployment device may include a delivery catheter assembly. The delivery catheter assembly may include a pliant member, wherein the pliant member is configured receive a vascular prosthesis. The pliant member may also be configured to aid in incrementally deploying a vascular prosthesis.

Abstract: RNA interference-based methods and products for inhibiting the expression of pathogenic dynamin-1 variants are provided. Delivery vehicles such as recombinant adeno-associated viruses deliver DNAs encoding RNAs that inhibit the expression of the dynamin-1 variants. The methods treat, for example, developmental and epileptic encephalopathies.

Abstract: The present disclosure relates to novel processes for the preparation of compounds of Formula I. Some of these compounds are useful as stimulators of soluble guanylate cyclase (sGC). Others are useful intermediates towards the preparation of said stimulators. These processes are amenable to large scale preparation and produce stable 3-(2-pyrimidinyl) pyrazoles of Formula I in high purity and yields. The present invention has the additional advantage of facile reaction conditions, amenable to scale up for large scale manufacturing. The disclosure also provides novel intermediates useful in the preparation of said compounds.

Abstract: A method and a system may inductively determine a position of a display screen of a computing device. Associated processes may generate a magnetic field by providing an alternating current to a driver coil, and may generate a voltage at a sensor coil in response to the magnetic field. The system and method may additionally include determining a linear position of the display screen by executing an algorithm at a processor. An input to the algorithm may include voltage data associated with the voltage generated at the sensor coil. The linear position of the display screen may correspond to a size of the display screen between a minimum size and a maximum size.

Abstract: Systems and methods for preventing the seeding of cancerous cells during morcellation of a tissue specimen inside a patient's body and removal of the tissue specimen from inside the patient through a minimally-invasive body opening to outside the patient are provided. One system includes a cut-resistant tissue guard removably insertable into a containment bag. The tissue specimen is isolated and contained within the containment bag and the guard is configured to protect the containment bag and surrounding tissue from incidental contact with sharp instrumentation used during morcellation and extraction of the tissue specimen. The guard is adjustable for easy insertion and removal and configured to securely anchor to the body opening. Protection-focused and containment-based systems for tissue removal are provided that enable minimally invasive procedures to be performed safely and efficiently.

Abstract: Atomic Layer Deposition (ALD) and Molecular Layer Deposition (MLD) provide precise and conformal coatings that are employed to modify the properties of powders for additive manufacturing (AM). We have surprisingly discovered that use of a limited number of ALD cycles can impart improved flowability. In various aspects, the coating may provide one or more advantages such as novel material properties, increased flowability, improved sintering, enhanced stability during storage, and prevention of premature sintering.

Abstract: A system for determining soil gas attributes includes a vacuum pump configured to draw soil gasses through an air intake; a gas sensor to measure gas concentration levels in soil gasses passing through the system; a GPS unit to identity the position of the system; and a controller configured to map measurements from the at least one gas sensor relative to a position of the system. An associated method of determining sod attributes includes the steps of drawing gas samples from the soil through an air intake; transmitting the gas samples to at least one gas sensor; measuring a gas concentration in the gas sample with the at least one gas sensor; transmitting the measured gas concentration to a controller; determining a position of the air intake with a GPS unit; transmitting the position to the controller; and mapping the measured gas concentration with the position.

Abstract: The present invention relates to a microfoaming aqueous ozone disinfection system that comprises an aqueous ozone generator that receives water, a microfoaming agent, and an electrochemical generator that comprises an ion exchange material. The electrochemical generator is integrated into the aqueous ozone generator. The electrochemical generator receives the water and generates from the water an ozonated concentrate liquid. The microfoaming aqueous ozone disinfection system also comprises a mixer that blends the microfoaming agent with the ozonated concentrate liquid creating a microfoaming ozonated liquid that is dispensed for use in disinfecting one or more surfaces. Replaceable cartridges can include the microfoaming agent. The system can data communicate with remote data processing resources, including communicating when it is time to replace the cartridge.

Abstract: The present disclosure relates to: a) crystalline forms of N—((R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide; b) pharmaceutical compositions comprising one or more crystalline forms of N—((R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide, and, optionally, one or more pharmaceutically acceptable carriers; c) methods of treating a tumor a cancer, or a Rasopathy disorder by administering one or more crystalline forms of N—((R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide to a subject in need thereof; and methods of producing essentially pure Form IV of N—((R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide.

Abstract: An inventive thermoset viscoelastomeric polymer and adhesive products thereof is provided. In some embodiments, an inventive adhesive product consists essentially of the thermoset viscoelastomeric polymer. In other embodiments, the thermoset viscoelastomeric polymer can be applied to a support member to provide an inventive adhesive product. In still other embodiments, the thermoset viscoelastomeric polymer can be applied to a conventional article to convert the article into an inventive adhesive product. The thermoset viscoelastomeric polymer and products thereof can comprise viscoelastic, adhesive, cohesive and releasability properties. In some embodiments, the thermoset viscoelastomeric polymer and products thereof can comprise cleansability and reusability properties. In further embodiments, the thermoset viscoelastomeric polymer and products thereof can comprise antimicrobial properties.

Abstract: A load lock in which the pumping speed is controlled so as to minimize the possibility of condensation is disclosed. The load lock is in communication with a vacuum pump and a valve. A controller is used to control the valve such that the supersaturation ratio within the load lock does not exceed a predetermined threshold, which is less than or equal to the critical value at which vapor condenses. In certain embodiments, a computer model is used to generate a profile, which may be a pumping speed profile or a pressure profile, and the valve is controlled according to the profile. In another embodiment, the load lock comprises a temperature sensor and a pressure sensor. The controller may calculate the supersaturation ratio based on these parameters and control the valve accordingly.

Abstract: A gas turbine engine includes a turbomachine having a compressor section, a combustion section, and a turbine section arranged in serial flow order. The turbomachine defines an engine inlet to an inlet duct, a fan duct inlet to a fan duct, and a core inlet to a core duct. The primary fan is driven by the turbomachine, and a secondary fan is located downstream of the primary fan within the inlet duct. One or more actuation devices operably associated with the fan duct, the one or more actuation devices actuable to increase or decrease an exit area of the fan duct.

Abstract: A washing appliance such as a dishwasher of the drawer-style, and a filter plate, filter and sump therefore. The filter plate of the washing appliance comprises a central inner opening to surround a wash pump, a perforated region towards the outer edge of the filter plate configured to filter wash liquid, and a filter opening in the perforated region of the filter plate, the filter opening for the insertion of a filter through the filter plate. The filter opening is at least partially located in a radial bulge of the filter plate.

Abstract: An imprinting apparatus includes a silicon master having a plurality of nanofeatures defined therein. An anti-stick layer coats the silicon master, the anti-stick layer including a molecule having a cyclosiloxane with at least one silane functional group. A method includes forming a master template by: depositing a formulation on a silicon master including a plurality of nanofeatures defined therein, the formulation including a solvent and a molecule having a cyclosiloxane with at least one silane functional group; and curing the formulation, thereby forming an anti-stick layer on the silicon master, the anti-stick layer including the molecule. The method further includes depositing a silicon-based working stamp material on the anti-stick layer of the master template; curing the silicon-based working stamp material to form a working stamp including a negative replica of the plurality of nanofeatures; and releasing the working stamp from the master template.

Abstract: Disclosed herein is a thioester-containing (meth)acrylate compound comprising at least two thioester moieties and at least 2 (meth)acrylate moieties and a method for making such compounds. These compounds can be used in (meth)acrylic resins as a crosslinking agent. Upon exposure to a nucleophilic solvent, cured (meth)acrylic resins derived from these thioester-containing (meth)acrylate compounds can be degraded.

Abstract: A thermal management system includes a thermal circuit having a thermal transport bus with a thermal fluid flowing therethrough. The thermal transport bus includes first and second bus segments. First and second thermal loads are on the first and second bus segments, respectively, and have different first and second inlet temperature requirements. The thermal management system includes a plurality of heat exchangers in thermal communication with the first and second thermal loads. The heat exchangers include a first heat exchanger and one or more second heat exchangers. The first heat exchanger is on one of the first or second bus segments for rejecting heat to engine fuel. The thermal fluid is split between each of the first and second bus segments such that only a portion of the thermal fluid flows through the first heat exchanger to accommodate the different first and second inlet temperature requirements.

Abstract: Some examples herein provide a sequencing flowcell that includes an imaging sensor; a hydrogel disposed on the imaging sensor and comprising a moiety; and a first complex non-covalently coupled to the moiety, the first complex comprising a first oligonucleotide. A method of using the sequencing flowcell may include decoupling the first complex from the moiety; and coupling a second complex to the moiety, the second complex comprising a second oligonucleotide. Methods of forming the flowcell are also provided.